Radical And Radical Ion Reactivity In Nucleic Acid Chemistry
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Radical And Radical Ion Reactivity In Nucleic Acid Chemistry
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Author : Michael D. Greenberg
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-22
Radical And Radical Ion Reactivity In Nucleic Acid Chemistry written by Michael D. Greenberg and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-22 with Science categories.
Comprehensive coverage of radical reactive intermediates in nucleic acid chemistry and biochemistry The Wiley Series on Reactive Intermediates in Chemistry and Biology investigates reactive intermediates from the broadest possible range of disciplines. The contributions in each volume offer readers fresh insights into the latest findings, emerging applications, and ongoing research in the field from a diverse perspective. The chemistry and biochemistry of reactive intermediates is central to organic chemistry and biochemistry, and underlies a significant portion of modern synthetic chemistry. Radical and Radical Ion Reactivity in Nucleic Acid Chemistry provides the only comprehensive review of the chemistry and biochemistry of nucleic acid radical intermediates. With contributions by world leaders in the field, the text covers a broad range of topics, including: A discussion of the relevant theory Ionization of DNA Nucleic acid sugar radicals Halopyrimidines Oxidative, reductive, and low energy electron transfer Electron affinity sensitizers Photochemical generative of reactive oxygen species Reactive nitrogen species Enediyne rearrangements Phenoxyl radicals A unique compilation on the cutting edge of our understanding, Radical and Radical Ion Reactivity in Nucleic Acid Chemistry provides an unparalleled resource to student and professional researchers in such fields as organic chemistry, biochemistry, molecular biology, and physical chemistry, as well as the industries associated with these disciplines.
Free Radical Induced Dna Damage And Its Repair
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Author : Clemens Sonntag
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-20
Free Radical Induced Dna Damage And Its Repair written by Clemens Sonntag and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-20 with Science categories.
The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced by ionizing radiation, but free-radical-induced DNA damage is a much more general phenomenon. It was, therefore, felt that it is now timely to review our present knowledge of free-radical-induced DNA damage induced by all conceivable free-radical-generating sources. Originally, it had been thought to include also a very important aspect, the repair of DNA damage by the cell’s various repair enzymes. Kevin Prise (Cancer Campaign, Gray Laboratory, L- don) was so kind to agree to write this part. However, an adequate description of this strongly expanding area would have exceeded the allocated space by much, and this section had to be omitted. The directors of the Max-Planck-Institut für Strahlenchemie (now MPI für Bioanorganische Chemie), Karl Wieghardt and Wolfgang Lubitz, kindly allowed me to continue to use its facilities after my retirement in 2001. Notably, our - brarian, Mrs. Jutta Theurich, and her right-hand help, Mrs. Rosemarie Schr- er, were most helpful in getting hold of the literature. I thank them very much. Without their constant help, this would have been very difficult indeed.
Applications Of Epr In Radiation Research
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Author : Anders Lund
language : en
Publisher: Springer
Release Date : 2014-10-20
Applications Of Epr In Radiation Research written by Anders Lund and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-20 with Science categories.
Applications of EPR in Radiation Research is a multi-author contributed volume presented in eight themes: I. Elementary radiation processes (in situ and low temperature radiolysis, quantum solids); II: Solid state radiation chemistry (crystalline, amorphous and heterogeneous systems); III: Biochemistry, biophysics and biology applications (radicals in biomaterials, spin trapping, free-radical-induced DNA damage); IV: Materials science (polymeric and electronic materials, materials for treatment of nuclear waste, irradiated food); V: Radiation metrology (EPR-dosimetry, retrospective and medical applications); VI: Geological dating; VII: Advanced techniques (PELDOR, ESE and ENDOR spectroscopy, matrix isolation); VIII: Theoretical tools (density-functional calculations, spectrum simulations).
Metal Ions In Biological Systems
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Author : Astrid Sigel
language : en
Publisher: CRC Press
Release Date : 1996-02-29
Metal Ions In Biological Systems written by Astrid Sigel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-02-29 with Science categories.
"Volume 33 focuses on the vibrant research area of probing nucleic acids--the carriers of the genetic code--by metal ion complexes of small molecules providing an authoritative, timely account of this fascinating topic by over 50 distinguished experts."
Encyclopedia Of Astrobiology
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Author : Muriel Gargaud
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-26
Encyclopedia Of Astrobiology written by Muriel Gargaud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-26 with Body, Mind & Spirit categories.
Astrobiology is a remarkably interdisciplinary field. This reference serves as a key to understanding technical terms from the different subfields of astrobiology, including astronomy, biology, chemistry, the geosciences and the space sciences.
Dna Damage Dna Repair And Disease
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Author : Miral Dizdaroglu
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-11-11
Dna Damage Dna Repair And Disease written by Miral Dizdaroglu and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-11 with Science categories.
The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.
Practical Aspects Of Computational Chemistry Iii
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Author : Jerzy Leszczynski
language : en
Publisher: Springer Science & Business
Release Date : 2014-04-23
Practical Aspects Of Computational Chemistry Iii written by Jerzy Leszczynski and has been published by Springer Science & Business this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-23 with Science categories.
Theoretical and Computational Chemistry research has made unparalleled advancements in understanding every expanding area of science and technology. This volume presents the state-of-the-art research and progress made by eminent researchers in the area of theoretical computational chemistry and physics. The title mirrors the name of the annual international conference “Conference on Current Trends on Computational Chemistry” (CCTCC) which has become a popular discussion ground for eminent Theoretical and Computational Chemists and has been honored by the presence of several Nobel Laureates. Practical Aspects of Computational Chemistry III is aimed at theoretical and computational chemists, physical chemists, material scientists and those who are eager to apply computational chemistry methods to problems of chemical and physical importance. The book is a valuable resource for undergraduate, graduate and PhD students as well as established researchers.
Handbook Of Computational Chemistry
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Author : Jerzy Leszczynski
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-13
Handbook Of Computational Chemistry written by Jerzy Leszczynski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-13 with Science categories.
The role the Handbook of Computational Chemistry is threefold. It is primarily intended to be used as a guide that navigates the user through the plethora of computational methods currently in use; it explains their limitations and advantages; and it provides various examples of their important and varied applications. This reference work is presented in three volumes. Volume I introduces the different methods used in computational chemistry. Basic assumptions common to the majority of computational methods based on molecular, quantum, or statistical mechanics are outlined and special attention is paid to the limits of their applicability. Volume II portrays the applications of computational methods to model systems and discusses in detail molecular structures, the modelling of various properties of molecules and chemical reactions. Both ground and excited states properties are covered in the gas phase as well as in solution. This volume also describes Nanomaterials and covers topics such as clusters, periodic, and nano systems. Special emphasis is placed on the environmental effects of nanostructures. Volume III is devoted to the important class of Biomolecules. Useful models of biological systems considered by computational chemists are provided and RNA, DNA and proteins are discussed in detail. This volume presents examples of calcualtions of their properties and interactions and reveals the role of solvents in biologically important reactions as well as the structure function relationship of various classes of Biomolecules.
Reviews In Computational Chemistry
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Author : Abby L. Parrill
language : en
Publisher: John Wiley & Sons
Release Date : 2015-04-29
Reviews In Computational Chemistry written by Abby L. Parrill and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-29 with Science categories.
The Reviews in Computational Chemistry series brings together leading authorities in the field to teach the newcomer and update the expert on topics centered around molecular modeling, such as computer-assisted molecular design (CAMD), quantum chemistry, molecular mechanics and dynamics, and quantitative structure-activity relationships (QSAR). This volume, like those prior to it, features chapters by experts in various fields of computational chemistry. Topics in Volume 28 include: Free-energy Calculations with Metadynamics Polarizable Force Fields for Biomolecular Modeling Modeling Protein Folding Pathways Assessing Structural Predictions of Protein-Protein Recognition Kinetic Monte Carlo Simulation of Electrochemical Systems Reactivity and Dynamics at Liquid Interfaces
Low Energy Electron Scattering From Molecules Biomolecules And Surfaces
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Author : Petr Carsky
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Low Energy Electron Scattering From Molecules Biomolecules And Surfaces written by Petr Carsky and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Science categories.
Since the turn of the 21st century, the field of electron molecule collisions has undergone a renaissance. The importance of such collisions in applications from radiation chemistry to astrochemistry has flowered, and their role in industrial processes such as plasma technology and lighting are vital to the advancement of next generation devices. F