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Radioimmunotherapy Of Cancer


Radioimmunotherapy Of Cancer
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Radioimmunotherapy Of Cancer


Radioimmunotherapy Of Cancer
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Author : Paul G. Abrams
language : en
Publisher: CRC Press
Release Date : 2000-07-11

Radioimmunotherapy Of Cancer written by Paul G. Abrams and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-07-11 with Medical categories.


Reflecting the past 20 years of intense research in radioimmunotherapy, this timely reference surveys an expansive breadth of topics on the evolving developments in radiation therapy. Placed in the context of advances in cancer treatment, chapters progress systematically from basic principles and properties of radionuclides to detailed summaries of



Radioimmunotherapy Of Cancer


Radioimmunotherapy Of Cancer
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Author : Paul G. Abrams
language : en
Publisher: CRC Press
Release Date : 2000-03-29

Radioimmunotherapy Of Cancer written by Paul G. Abrams and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-03-29 with Medical categories.


Reflecting the past 20 years of intense research in radioimmunotherapy, this timely reference surveys an expansive breadth of topics on the evolving developments in radiation therapy. Placed in the context of advances in cancer treatment, chapters progress systematically from basic principles and properties of radionuclides to detailed summaries of current cancer therapies. Up to date, clearly organized, and thorough-sure to become a standard in the field! Providing comprehensive treatment on radiolabeled antibody therapy, Radioimmunotherapy of Cancer reviews dosimetric principles and clinical dosimetry of radioimmunotherapy in the targeting and delivery of radiation describes tumor architectures and outlines novel constructs for radionuclide delivery analyzes a variety of improved targeting approaches, including pretargeting contextual analysis of extracorporeal techniques in radioimmunotherapy details studies from the radiotherapy of lymphoma, solid tumors, and ovarian cancer and the targeted radiotherapy of neuroblastoma and squamous head and neck cancer and much more! With contributions from nearly 50 international experts and containing over 1300 literature references, drawings, photographs, tables, and equations, Radioimmunotherapy of Cancer is an invaluable and indispensable reference for physicians in nuclear medicine and medical physicists; oncologists, radiologists, radiochemists, and radiopharmacists; immunologists, pulmonologists, and cancer researchers; pharmacologists and drug delivery pharmaceutical chemists; and upper-level undergraduate, graduate, and medical school students in these disciplines.



Cancer Therapy With Radiolabeled Antibodies


Cancer Therapy With Radiolabeled Antibodies
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Author : David M. Goldenberg
language : en
Publisher: CRC Press
Release Date : 2018-01-18

Cancer Therapy With Radiolabeled Antibodies written by David M. Goldenberg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Law categories.


Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading experts examine the problems and prospects of RAIT from radiation, immunological, chemical, physical, physiological, and clinical perspectives with both overviews and original research. Discussions cover the up-to-date clinical results in the RAIT of ovarian, breast, colorectal, and brain cancers, as well as the current status of RAIT in the management of B cell lymphomas. Radiobiology, dosimetry, radiochemistry, targeting biology in experimental models, clinical experiences in hematopoietic and solid tumors, and new approaches to improve cancer radioimmunotherapy are also discussed. In addition, new dosimetry concepts, new labeling methods, new concepts of antibody pharmacokinetics, and new methods to enhance selective cancer radioimmunotherapy are included.



Radioimmunotherapy Translational Opportunities And Challenges


Radioimmunotherapy Translational Opportunities And Challenges
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Author : Udo S. Gaipl
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-13

Radioimmunotherapy Translational Opportunities And Challenges written by Udo S. Gaipl and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-13 with categories.




Cancer Radioimmunotherapy


Cancer Radioimmunotherapy
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Author : Pietro Riva
language : en
Publisher: CRC Press
Release Date : 1998-09-01

Cancer Radioimmunotherapy written by Pietro Riva and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-09-01 with Medical categories.


This book represents an update of investigations devoted to the utilization of new biological probes, conjugated to suitable radioisotopes, for the treatment of different solid and hematological tumors. Much progress has been made since the original findings of monoclonal antibodies, but several problems have to be resolved before this particular therapeutic approach can be applied extensively.



Monoclonal Antibody And Peptide Targeted Radiotherapy Of Cancer


Monoclonal Antibody And Peptide Targeted Radiotherapy Of Cancer
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Author : Raymond M. Reilly
language : en
Publisher: John Wiley & Sons
Release Date : 2010-12-28

Monoclonal Antibody And Peptide Targeted Radiotherapy Of Cancer written by Raymond M. Reilly and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-28 with Science categories.


Oncology Book of 2011, British Medical Association's Medical Book Awards Awarded first prize in the Oncology category at the 2011 BMA Medical Book Awards, Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer helps readers understand this hot pharmaceutical field with up-to-date developments. Expert discussion covers a range of diverse topics associated with this field, including the optimization of design of biomolecules and radiochemistry, cell and animal models for preclinical evaluation, discoveries from key clinical trials, radiation biology and dosimetry, and considerations in regulatory approval. With chapters authored by internationally renowned experts, this book delivers a wealth of information to push future discovery.



Targeted Radionuclide Therapy


Targeted Radionuclide Therapy
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Author : Tod W. Speer
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2012-03-28

Targeted Radionuclide Therapy written by Tod W. Speer and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-28 with Medical categories.


Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.



Systemic Radiotherapy With Monoclonal Antibodies


Systemic Radiotherapy With Monoclonal Antibodies
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Author : Marie-Luise Sautter-Bihl
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Systemic Radiotherapy With Monoclonal Antibodies written by Marie-Luise Sautter-Bihl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Almost a century ago Paul Ehrlich introduced the "magic bullet" concept of targeting therapeutic agents to specific tissues in order to reduce systemic toxicity. Due to the advances in hybridoma technology in the 1980s, monoclonal antibodies (MAbs) with their exquisite affinity to tumor antigens have become powerful tools in the treatment of cancer, especially when linked to therapeutic agents such as radionuclides, drugs, toxins, or enzymes. It can now be expected that such agents will lead to new cancer treatments with high therapeutic success rates. However, there are major problems in developing this therapeutic concept to a routine treatment modality. This is partly due to factors such as heterogenous distribution of tumor antigens, insufficient blood supply of tumors, high interstitial pressure, and the large interstitial space that antibodies have to traverse. This book is focused on the development in radio immunotherapy (RIT) using radio labeled monoclonal antibodies as tumoritoxic agents. This area of research has attracted the interest of clinicians and scientists from many different disciplines. It is now clear that the full potential of RIT can only be realized through the concerted efforts of laboratory scientists (molecular biologists, cell physiologists, chemists, radiation physicists, and biologists) and cancer clinicians in nuclear medicine, radiooncology, and internal oncology.



Radioimmunoimaging And Radioimmunotherapy


Radioimmunoimaging And Radioimmunotherapy
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Author : Scott W. Burchiel
language : en
Publisher: Elsevier Publishing Company
Release Date : 1983

Radioimmunoimaging And Radioimmunotherapy written by Scott W. Burchiel and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.




Radioimmunotherapy Translational Opportunities And Challenges


Radioimmunotherapy Translational Opportunities And Challenges
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Author : Udo S. Gaipl
language : en
Publisher:
Release Date : 2020

Radioimmunotherapy Translational Opportunities And Challenges written by Udo S. Gaipl and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.


Surgery, chemotherapy and radiotherapy remain the three primary approaches for treating the majority of cancers. Although the primary aim of radiotherapy is to inhibit tumor cell proliferation and induce tumor cell death by inducing DNA double-strand breaks, it is also known to have a number of immunological effects, the manipulation of which could enhance clinical efficacy. Recent insights into the immunomodulatory capacity of tumours, and the development of approaches to therapeutically exploit these have prompted the emergence of a range of immunotherapeutic approaches for inducing and enhancing robust, protective anti-tumor immunity. Combining radiotherapy with immunotherapy (radioimmunotherapy) therefore has significant clinical potential. The aim of this Research Topic is to collate primary articles, reviews and opinion pieces on the complex reciprocal relationships between the immune system, tumors and the tumour microenvironment, and the stimulatory and suppressive effects of radiotherapy on innate and adaptive immunity in the pre-clinical and clinical settings.