Radiopharmaceuticals
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Handbook Of Radiopharmaceuticals
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Author : Michael J. Welch
language : en
Publisher: John Wiley & Sons
Release Date : 2003-01-17
Handbook Of Radiopharmaceuticals written by Michael J. Welch and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-17 with Medical categories.
A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States
Radiopharmaceuticals In Nuclear Pharmacy And Nuclear Medicine
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Author : Richard J. Kowalsky
language : en
Publisher: American Pharmacists Association (APhA)
Release Date : 2004
Radiopharmaceuticals In Nuclear Pharmacy And Nuclear Medicine written by Richard J. Kowalsky and has been published by American Pharmacists Association (APhA) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
"Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, 2nd edition," is an essential reference for nuclear pharmacy practitioners, nuclear medicine technologists, and nuclear medicine physicians. It will also be useful as a textbook in programs that educate these practitioners. The first 12 chapters cover radioactive decay, radiation detection and measurement, radiation protection and risk, radiation safety, radiation biology, licensing and regulatory controls, radionuclide production, radiopharmaceutical chemistry, radiopharmaceuticals for positron emission tomography (PET), the nuclear pharmacy, and quality control. Four of these chapters are written by contributing authors. Together the 12 chapters, all written by nuclear pharmacy practitioners, present the information needed for a pharmacist to become an authorized nuclear pharmacist. The remaining 11 chapters cover the diagnostic and therapeutic use of radiopharmaceuticals. Chapters on specific body systems (brain, thyroid, heart, lung, liver, spleen, gastrointestinal tract, kidney, and bone) are followed by chapters on total body procedures, monoclonal antibodies, in vivo function studies, and therapeutic radiopharmaceuticals. Key Features *Updates its predecessor, Radiopharmaceuticals in Nuclear Medicine Practice, to include new material in areas such as radiation biology, radiopharmaceuticals used in PET, and therapeutic radiopharmaceuticals. *Features expanded coverage of nuclear medicine applications of radiopharmaceuticals useful for nuclear pharmacy practitioners. *Some 150 tables and nearly 450 figures enrich and illustrate the text, and each chapter is referenced to the primary literature. About the Authors: Richard J. Kowalsky, PharmD, BCNP, FAPhA, is Associate Professor of Pharmacy, School of Pharmacy, and Associate Professor of Radiology, Department of Radiology, University of North Carolina at Chapel Hill. He is Director of the Nuclear Pharmacy at UNC Hospitals, where he has practiced for 32 years. Steven W. Falen, MD, PhD, is former Director of Positron Emission Tomography and Assistant Professor of Radiology and Biomedical Engineering, Department of Radiology, University of North Carolina at Chapel Hill. He is now Director of Nuclear Medicine and PET Services, Riverside Regional Medical Center, Newport News, Virginia.
The Handbook Of Radiopharmaceuticals
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Author : Azuwuike Owunwanne
language : en
Publisher: Springer
Release Date : 2012-12-06
The Handbook Of Radiopharmaceuticals written by Azuwuike Owunwanne and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
One Radiobiopharmaceutics.- 1 Preparation of radiopharmaceuticals.- Production of radionuclides.- Synthesis of the non-radioactive compound.- Reaction of the radionuclide with the non-radioactive compound.- References.- 2 Ideal characteristics of radiopharmaceuticals.- Availability and cost.- Preparation.- Biologic behavior.- Radionuclidic characteristics.- Hematology.- 3 Quality control of radiopharmaceuticals.- Biologic tests.- Physicochemical tests.- References.- 4 Design of radiopharmaceuticals.- Radionuclide.- Chemistry.- Biology.- Human studies.- Registration.- References.- 5 The fate of.
Radiopharmaceuticals In Nuclear Medicine Practice
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Author : Richard J. Kowalsky
language : en
Publisher:
Release Date : 1987
Radiopharmaceuticals In Nuclear Medicine Practice written by Richard J. Kowalsky and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Nuclear medicine categories.
Handbook Of Radiopharmaceuticals
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Author : Michael R. Kilbourn
language : en
Publisher: John Wiley & Sons
Release Date : 2021-04-12
Handbook Of Radiopharmaceuticals written by Michael R. Kilbourn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-12 with Science categories.
The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.
Radiopharmaceuticals For Therapy
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Author : F. F. (Russ) Knapp
language : en
Publisher: Springer
Release Date : 2016-01-20
Radiopharmaceuticals For Therapy written by F. F. (Russ) Knapp and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-20 with Medical categories.
This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.
Fundamentals Of Nuclear Pharmacy
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Author : Gopal B. Saha
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Fundamentals Of Nuclear Pharmacy written by Gopal B. Saha and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
A new edition of a book is warranted when the book is successful and there are many new developments in the related discipline. Both have occurred for this book during the past 7 years since its second edition. The growth and development in nuclear pharmacy and radiopharmaceutical chemistry along with the continued success of the book have convinced us to update the book; hence this third edition. This book is a ramification of my nuclear pharmacy courses offered to pharmacy students specializing in nuclear pharmacy, nuclear medicine resi dents, and nuclear medicine technology students. The book is written in an integrated form from the basic concept of atomic structure to the practical clinical uses of radiopharmaceuticals. It serves both as a textbook on nu clear pharmacy for pharmacy students and nuclear medicine technologists, and as a useful reference book for many professionals related to nuclear medicine, such as nuclear medicine physicians and radiologists. The book contains 12 chapters. Each chapter is written as comprehen sively as possible based on my personal experience and understanding. At the end of each chapter, a section of pertinent questions and problems and so me suggested reading materials are included. I have made justifiably many additions and deletions as weIl as some reorganization in this edition. Chapter 3 is entirely dedicated to instru ments for radiation detection and measurement, including brief description of gas detectors, gamma-detecting instruments, and tomographic scanners.
Safety And Efficacy Of Radiopharmaceuticals
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Author : Knud Kristensen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Safety And Efficacy Of Radiopharmaceuticals written by Knud Kristensen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Safety and efficacy of radiopharmaceuticals are elements of great importance in nuclear medicine. Since the first meeting in 1965 in Oak Ridge with the title Radiopharmaceuticals tremendous developments have taken place. In 1965 the whole technetium-99m area was just in its very beginning. Safety and efficacy of the non-radioactive pharmaceuticals have attracted great attention during the last 10 years and so have similar aspects of radiopharmaceuticals during the later years. Regulatory agencies are extending their work also to the preparation of radiopharmaceuticals at hospitals and to requirements for registration of radiopharmaceuticals. In a fast developing field there might be tendencies to confrontation between interests and there have certainly been some tendencies to put undue restrictions on the use of radio pharmaceuticals due to the lack of understanding between the industry and the regulatory authorities and between regulatory authorities and hospitals. Much of this may have been due to lack of information and certainly is due to the lack of fundamental scientific knowledge in many radiopharmaceutical aspects. A fast and safe introduction of new radio pharmaceuticals and the proper handling of these requires a lot of development work, but also an understanding of how general principles from the non-radioactive drug field may be sensibly transformed into the radiopharmaceutical area. It may even require compromises between requirements for safety in different areas such as radiation protection and pharmaceutical aspects.
Radiopharmaceuticals For Positron Emission Tomography Volume 1
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Author : Peter J. H. Scott
language : en
Publisher: John Wiley & Sons
Release Date : 2012-03-13
Radiopharmaceuticals For Positron Emission Tomography Volume 1 written by Peter J. H. Scott and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-13 with Science categories.
The ultimate reference guide to the synthesis of radiopharmaceuticals The Radiochemical Syntheses series provides scientists and professionals with a comprehensive reference to proven synthetic methods for radiochemical reactions, along with step-by-step guidance on how to replicate these syntheses in the laboratory. Volume 1 in the series focuses on the synthesis and purification of radiopharmaceuticals in clinical use today. It brings together in one complete, self-contained volume a collection of monographs containing a wealth of practical information from across the literature, demonstrating in meticulous detail how to prepare radiopharmaceuticals for positron emission tomography (PET) imaging, especially in tumor studies, cardiology, and neuroscience. Readers have key experimental details culled from the literature at their fingertips, greatly simplifying the process of qualifying a site for the clinical production of new radiopharmaceuticals.
Radiopharmaceutical Chemistry
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Author : Jason S. Lewis
language : en
Publisher: Springer
Release Date : 2019-04-02
Radiopharmaceutical Chemistry written by Jason S. Lewis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-02 with Medical categories.
This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.