Ravenous Otto Warburg The Nazis And The Search For The Cancer Diet Connection
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Ravenous Otto Warburg The Nazis And The Search For The Cancer Diet Connection
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Author : Sam Apple
language : en
Publisher: Liveright Publishing
Release Date : 2021-05-25
Ravenous Otto Warburg The Nazis And The Search For The Cancer Diet Connection written by Sam Apple and has been published by Liveright Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-25 with Science categories.
The extraordinary story of the Nazi-era scientific genius who discovered how cancer cells eat—and what it means for how we should. The Nobel laureate Otto Warburg—a cousin of the famous finance Warburgs—was widely regarded in his day as one of the most important biochemists of the twentieth century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it. In Ravenous, Sam Apple reclaims Otto Warburg as a forgotten, morally compromised genius who pursued cancer single-mindedly even as Europe disintegrated around him. While the vast majority of Jewish scientists fled Germany in the anxious years leading up to World War II, Warburg remained in Berlin, working under the watchful eye of the dictatorship. With the Nazis goose-stepping their way across Europe, systematically rounding up and murdering millions of Jews, Warburg awoke each morning in an elegant, antiques-filled home and rode horses with his partner, Jacob Heiss, before delving into his research at the Kaiser Wilhelm Society. Hitler and other Nazi leaders, Apple shows, were deeply troubled by skyrocketing cancer rates across the Western world, viewing cancer as an existential threat akin to Judaism or homosexuality. Ironically, they viewed Warburg as Germany’s best chance of survival. Setting Warburg’s work against an absorbing history of cancer science, Apple follows him as he arrives at his central belief that cancer is a problem of metabolism. Though Warburg’s metabolic approach to cancer was considered groundbreaking, his work was soon eclipsed in the early postwar era, after the discovery of the structure of DNA set off a search for the genetic origins of cancer. Remarkably, Warburg’s theory has undergone a resurgence in our own time, as scientists have begun to investigate the dangers of sugar and the link between obesity and cancer, finding that the way we eat can influence how cancer cells take up nutrients and grow. Rooting his revelations in extensive archival research as well as dozens of interviews with today’s leading cancer authorities, Apple demonstrates how Warburg’s midcentury work may well hold the secret to why cancer became so common in the modern world and how we can reverse the trend. A tale of scientific discovery, personal peril, and the race to end a disastrous disease, Ravenous would be the stuff of the most inventive fiction were it not, in fact, true.
Ravenous
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Author : Sam Apple
language : en
Publisher: National Geographic Books
Release Date : 2021-05-25
Ravenous written by Sam Apple and has been published by National Geographic Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-25 with Science categories.
The extraordinary story of the Nazi-era scientific genius who discovered how cancer cells eat—and what it means for how we should. The Nobel laureate Otto Warburg—a cousin of the famous finance Warburgs—was widely regarded in his day as one of the most important biochemists of the twentieth century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it. In Ravenous, Sam Apple reclaims Otto Warburg as a forgotten, morally compromised genius who pursued cancer single-mindedly even as Europe disintegrated around him. While the vast majority of Jewish scientists fled Germany in the anxious years leading up to World War II, Warburg remained in Berlin, working under the watchful eye of the dictatorship. With the Nazis goose-stepping their way across Europe, systematically rounding up and murdering millions of Jews, Warburg awoke each morning in an elegant, antiques-filled home and rode horses with his partner, Jacob Heiss, before delving into his research at the Kaiser Wilhelm Society. Hitler and other Nazi leaders, Apple shows, were deeply troubled by skyrocketing cancer rates across the Western world, viewing cancer as an existential threat akin to Judaism or homosexuality. Ironically, they viewed Warburg as Germany’s best chance of survival. Setting Warburg’s work against an absorbing history of cancer science, Apple follows him as he arrives at his central belief that cancer is a problem of metabolism. Though Warburg’s metabolic approach to cancer was considered groundbreaking, his work was soon eclipsed in the early postwar era, after the discovery of the structure of DNA set off a search for the genetic origins of cancer. Remarkably, Warburg’s theory has undergone a resurgence in our own time, as scientists have begun to investigate the dangers of sugar and the link between obesity and cancer, finding that the way we eat can influence how cancer cells take up nutrients and grow. Rooting his revelations in extensive archival research as well as dozens of interviews with today’s leading cancer authorities, Apple demonstrates how Warburg’s midcentury work may well hold the secret to why cancer became so common in the modern world and how we can reverse the trend. A tale of scientific discovery, personal peril, and the race to end a disastrous disease, Ravenous would be the stuff of the most inventive fiction were it not, in fact, true.
Schlepping Through The Alps
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Author : Sam Apple
language : en
Publisher: Ballantine Books
Release Date : 2009-01-16
Schlepping Through The Alps written by Sam Apple and has been published by Ballantine Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-16 with Travel categories.
Hans Breuer, Austria’s only wandering shepherd, is also a Yiddish folksinger. He walks the Alps, shepherd’s stick in hand, singing lullabies to his 625 sheep. Sometimes he even gives concerts in historically anti-Semitic towns, showing slides of the flock as he belts out Yiddish ditties. When New York-based writer Sam Apple hears about this one-of-a-kind eccentric, he flies overseas and signs on as a shepherd’s apprentice. For thoroughly urban, slightly neurotic Sam, stumbling along in borrowed boots and burdened with a lot more baggage than his backpack, the task is far from a walk in Central Park. Demonstrating no immediate natural talent for shepherding, he tries to earn the respect of Breuer’s sheep, while keeping a safe distance from the shepherd’s fierce herding dogs. As this strange and hilarious adventure unfolds, the unlikely duo of Sam and Hans meander through a paradise of woods and high meadows toward awkward encounters with Austrians of many stripes. Apple is determined to find out if there are really as many anti-Semites in Austria as he fears and to understand how Hans, who grew up fighting the lingering Nazism in Vienna, became a wandering shepherd. What Apple discovers turns out to be far more fascinating than he had imagined. With this odd and wonderful book, Sam Apple joins the august tradition of Tony Horwitz and Bill Bryson. Schlepping Through the Alps is as funny as it is moving.
Rush
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Author : Stephen Fried
language : en
Publisher: Crown
Release Date : 2018-09-04
Rush written by Stephen Fried and has been published by Crown this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-04 with Biography & Autobiography categories.
The monumental life of Benjamin Rush, medical pioneer and one of our most provocative and unsung Founding Fathers FINALIST FOR THE GEORGE WASHINGTON BOOK PRIZE • AMERICAN LIBRARY ASSOCIATION NOTABLE BOOK OF THE YEAR By the time he was thirty, Dr. Benjamin Rush had signed the Declaration of Independence, edited Common Sense, toured Europe as Benjamin Franklin’s protégé, and become John Adams’s confidant, and was soon to be appointed Washington’s surgeon general. And as with the greatest Revolutionary minds, Rush was only just beginning his role in 1776 in the American experiment. As the new republic coalesced, he became a visionary writer and reformer; a medical pioneer whose insights and reforms revolutionized the treatment of mental illness; an opponent of slavery and prejudice by race, religion, or gender; an adviser to, and often the physician of, America’s first leaders; and “the American Hippocrates.” Rush reveals his singular life and towering legacy, installing him in the pantheon of our wisest and boldest Founding Fathers. Praise for Rush “Entertaining . . . Benjamin Rush has been undeservedly forgotten. In medicine . . . [and] as a political thinker, he was brilliant.”—The New Yorker “Superb . . . reminds us eloquently, abundantly, what a brilliant, original man Benjamin Rush was, and how his contributions to . . . the United States continue to bless us all.”—The Philadelphia Inquirer “Perceptive . . . [a] readable reassessment of Rush’s remarkable career.”—The Wall Street Journal “An amazing life and a fascinating book.”—CBS This Morning “Fried makes the case, in this comprehensive and fascinating biography, that renaissance man Benjamin Rush merits more attention. . . . Fried portrays Rush as a complex, flawed person and not just a list of accomplishments; . . . a testament to the authorial thoroughness and insight that will keep readers engaged until the last page.”—Publishers Weekly (starred review) “[An] extraordinary and underappreciated man is reinstated to his rightful place in the canon of civilizational advancement in Rush. . . . Had I read Fried’s Rush before the year’s end, it would have crowned my favorite books of 2018 . . . [a] superb biography.”—Brain Pickings
Eating Nature In Modern Germany
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Author : Corinna Treitel
language : en
Publisher: Cambridge University Press
Release Date : 2017-04-27
Eating Nature In Modern Germany written by Corinna Treitel and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-27 with Cooking categories.
A study of vegetarianism, raw food diets, organic farming, and other 'natural' ways to eat and farm in Germany since 1850.
The Demon Under The Microscope
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Author : Thomas Hager
language : en
Publisher: Crown
Release Date : 2006-09-19
The Demon Under The Microscope written by Thomas Hager and has been published by Crown this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-19 with Science categories.
In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of sulfa, the first antibiotic and the drug that shaped modern medicine. The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. Sulfa saved millions of lives—among them those of Winston Churchill and Franklin Delano Roosevelt Jr.—but its real effects are even more far reaching. Sulfa changed the way new drugs were developed, approved, and sold; transformed the way doctors treated patients; and ushered in the era of modern medicine. The very concept that chemicals created in a lab could cure disease revolutionized medicine, taking it from the treatment of symptoms and discomfort to the eradication of the root cause of illness. A strange and colorful story, The Demon Under the Microscope illuminates the vivid characters, corporate strategy, individual idealism, careful planning, lucky breaks, cynicism, heroism, greed, hard work, and the central (though mistaken) idea that brought sulfa to the world. This is a fascinating scientific tale with all the excitement and intrigue of a great suspense novel.
The Metabolism Of Tumours
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Author : Otto Warburg
language : en
Publisher: EnCognitive.com
Release Date : 2015-09-15
The Metabolism Of Tumours written by Otto Warburg and has been published by EnCognitive.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-15 with Health & Fitness categories.
This is the original text of Nobel Prize Laureate Dr. Otto Warburg's classic, "The Metabolism of Tumours." In this book Dr. Warburg, MD, PhD, and distinguished scientists demonstrate, through empirical evidence that: “Cancer, above all other diseases, has countless secondary causes. But, even for cancer, there is only one prime cause. Summarized in a few words, the prime cause of cancer is the replacement of the respiration of oxygen in normal body cells by fermentation of sugar.” All the experiments, in their original text, are included in this book.
The Pandemic Century
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Author : Mark Honigsbaum
language : en
Publisher: Oxford University Press
Release Date : 2019-03-09
The Pandemic Century written by Mark Honigsbaum and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-09 with History categories.
Like sharks, epidemic diseases always lurk just beneath the surface. This fast-paced history of their effect on mankind prompts questions about the limits of scientific knowledge, the dangers of medical hubris, and how we should prepare as epidemics become ever more frequent. Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet, despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu and the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 'parrot fever' pandemic and the more recent SARS, Ebola, and Zika epidemics, the last 100 years have been marked by a succession of unanticipated pandemic alarms. Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behaviour and technologies play in the emergence and spread of microbial diseases.
Dr Otto Warburg S Cancer Research Papers
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Author : Otto Warburg
language : en
Publisher: EnCognitive.com
Release Date : 2015-12-04
Dr Otto Warburg S Cancer Research Papers written by Otto Warburg and has been published by EnCognitive.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-04 with Health & Fitness categories.
This collection includes the original cancer research papers by Dr. Otto Warburg and his colleagues in their original text. It includes additional articles NOT found in “The Metabolism of Tumours.” The collection includes these articles: —The Prime Cause and Prevention of Cancer —On the Origin of Cancer Cells —The Metabolism of Tumours in the Body —On the Respiratory Impairment of Cancer Cells —The Chemical Constitution of Respiration Ferment —The Oxygen Transferring Ferment of Respiration —The Metabolism of Carcinoma Cells —The Carbohydrate Metabolism of Tumours —Observation on the Carbohydrate Metabolism of Tumours —Enzymic Studies on Ascitic Tumours and Their Host’s Blood Plasmas If a lowered oxygen pressure during cell growth may cause cancer, or, more generally, if any inhibition of respiration during growth may cause cancer, then a next problem is to show why reduced respiration induces cancer. Since we already know that with a lowering of respiration fermentation results, we can re- express our question: Why does cancer result if oxygen-respiration is replaced by fermentation? The early history of life on our planet indicates that life existed on earth before the earth’s atmosphere contained free oxygen gas. The living cells must therefore have been fermenting cells then, and, as fossils show, they were undifferentiated single cells. Only when free oxygen appeared in the atmosphere - some billion years ago - did the higher development of life set in, to produce the plant and animal kingdoms from the fermenting, undifferentiated single cells. What the philosophers of life have called "Evolution créatrice" has been and is therefore the work of oxygen. The reverse process, the dedifferentiation of life, takes place today in greatest amount before our eyes in cancer development, which is another expression for dedifferentiation. To be sure, cancer development takes place even in the presence of free oxygen gas in the atmosphere, but this oxygen may not penetrate in sufficient quantity into the growing body cells, or the respiratory apo-enzymes of the growing body cells may not be saturated with the active groups. In any case, during the cancer development the oxygen-respiration always falls, fermentation appears, and the highly differentiated cells are transformed to fermenting anaerobes, which have lost all their body functions and retain only the now useless property of growth. Thus, when respiration disappears, life does not disappear, but the meaning of life disappears, and what remains are growing machines that destroy the body in which they grow.
The Gene Machine
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Author : Bonnie Rochman
language : en
Publisher: Scientific American / Farrar, Straus and Giroux
Release Date : 2017-02-28
The Gene Machine written by Bonnie Rochman and has been published by Scientific American / Farrar, Straus and Giroux this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-28 with Family & Relationships categories.
A sharp-eyed exploration of the promise and peril of having children in an age of genetic tests and interventions Is screening for disease in an embryo a humane form of family planning or a slippery slope toward eugenics? Should doctors tell you that your infant daughter is genetically predisposed to breast cancer? If tests revealed that your toddler has a genetic mutation whose significance isn’t clear, would you want to know? In The Gene Machine, the award-winning journalist Bonnie Rochman deftly explores these hot-button questions, guiding us through the new frontier of gene technology and how it is transforming medicine, bioethics, health care, and the factors that shape a family. Rochman tells the stories of scientists working to unlock the secrets of the human genome; genetic counselors and spiritual advisers guiding mothers and fathers through life-changing choices; and, of course, parents (including Rochman herself) grappling with revelations that are sometimes joyous, sometimes heartbreaking, but always profound. She navigates the dizzying and constantly expanding array of prenatal and postnatal tests, from carrier screening to genome sequencing, while considering how access to more tests is altering perceptions of disability and changing the conversation about what sort of life is worth living and who draws the line. Along the way, she highlights the most urgent ethical quandary: Is this technology a triumph of modern medicine or a Pandora’s box of possibilities? Propelled by human narratives and meticulously reported, The Gene Machine is both a scientific road map and a meditation on our power to shape the future. It is a book that gets to the very core of what it means to be human.