Recent Advances In Electron Cryomicroscopy
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Recent Advances In Electron Cryomicroscopy
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Author : Steven J. Ludtke
language : en
Publisher: Academic Press
Release Date : 2011
Recent Advances In Electron Cryomicroscopy written by Steven J. Ludtke and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Biochemistry categories.
Electron cryomicroscopy, is a form of transmission electron microscopy (EM) where the sample is studied at cryogenic temperatures (generally liquid nitrogen temperatures). Cryo-EM is developing popularity in structural biology. This volume from the Advances in Protein Chemistry and Structural Biology series is Part B and covers essential topics.
Recent Advances In Electron Cryomicroscopy Part B
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Author : STEVEN J. LUDTKE.
language : en
Publisher:
Release Date : 2011
Recent Advances In Electron Cryomicroscopy Part B written by STEVEN J. LUDTKE. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Annotation Electron cryomicroscopy is a form of transmission electron microscopy (EM) where the sample is studied at cryogenic temperatures (generally liquid nitrogen temperatures). Cryo-EM is developing popularity in structural biology. This volume covers essential topics.
Recent Advances In Electron Cryomicroscopy
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Author :
language : en
Publisher: Academic Press
Release Date : 2010-11-25
Recent Advances In Electron Cryomicroscopy written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-25 with Science categories.
Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission
The Resolution Revolution Recent Advances In Cryoem
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-08-26
The Resolution Revolution Recent Advances In Cryoem written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-26 with Medical categories.
cryoEM, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods and new developments in recording images, the creation, evaluation and validation of 3D maps from the images, model building into maps and refinement of the resulting atomic structures, and applications of essentially single particle methods to helical structures and to sub-tomogram averaging. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods that determine the structures of biological molecules, a vital step for understanding their function Contains the technical developments underpinning the advances of cryoEM and captures the exciting insights that have resulted
Recent Advances In Electron And Light Optical Imaging In Biology And Medicine
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Author : Andrew Paul Somlyo
language : en
Publisher:
Release Date : 1986
Recent Advances In Electron And Light Optical Imaging In Biology And Medicine written by Andrew Paul Somlyo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Science categories.
Single Particle Cryo Electron Microscopy
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Author : Joachim Frank
language : en
Publisher: World Scientific Publishing Company
Release Date : 2017-12-31
Single Particle Cryo Electron Microscopy written by Joachim Frank and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-31 with Electron microscopy categories.
The book reproduces 55 of more than 300 articles written by the author, representing milestones in methods development of single-particle cryo-EM as well as important results obtained by this technique in the study of biological macromolecules and their interactions. Importantly, neither symmetries nor ordered arrangements (as in two-dimensional crystals, helical assemblies, icosahedral viruses) are required. Although the biological applications are mainly in the area of ribosome structure and function, the elucidation of membrane channel structures and their activation and gating mechanisms are represented, as well. The book is introduced by a commentary that explains the original development of concepts, describes the contributions of the author's colleagues and students, and shows how challenges were overcome as the technique matured. Along the way, the ribosome served as an example for a macromolecule with intricate structure and conformational dynamics that pose challenges for three-dimensional visualization. Toward the end of the book -- bringing us to the present time -- molecular structures with near-atomic resolution are presented, and a novel type of computational analysis, manifold embedding, is introduced. Single-particle cryo-EM is currently revolutionizing structural biology, presenting a powerful alternative to X-ray crystallography as a means to solve the structure of biological macromolecules. The book presents in one place a number of articles containing key advances in mathematical and computational methods leading up to the present time. Secondly, the development of the technique over the years is reflected by ever-expanding discoveries in the field of ribosome structure and function. Thirdly, as all histories of ideas, the history of concepts pertaining to this new method of visualization is fascinating all in itself.
Single Particle Cryo Electron Microscopy
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Author : Joachim Frank
language : en
Publisher:
Release Date : 2018
Single Particle Cryo Electron Microscopy written by Joachim Frank and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Electron microscopy categories.
Advances In Optical And Electron Microscopy
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Author : R. Barer
language : en
Publisher:
Release Date : 1971
Advances In Optical And Electron Microscopy written by R. Barer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Electron microscopy categories.
Correlative Imaging
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Author : Paul Verkade
language : en
Publisher: John Wiley & Sons
Release Date : 2019-11-04
Correlative Imaging written by Paul Verkade and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-04 with Science categories.
Brings a fresh point of view to the current state of correlative imaging and the future of the field This book provides contributions from international experts on correlative imaging, describing their vision of future developments in the field based on where it is today. Starting with a brief historical overview of how the field evolved, it presents the latest developments in microscopy that facilitate the correlative workflow. It also discusses the need for an ideal correlative probe, applications in proteomic and elemental analysis, interpretation methods, and how correlative imaging can incorporate force microscopy, soft x-ray tomography, and volume electron microscopy techniques. Work on placing individual molecules within cells is also featured. Correlative Imaging: Focusing on the Future offers in-depth chapters on: correlative imaging from an LM perspective; the importance of sample processing for correlative imaging; correlative light and volume EM; correlation with scanning probe microscopies; and integrated microscopy. It looks at: cryo-correlative microscopy; correlative cryo soft X-ray imaging; and array tomography. Hydrated-state correlative imaging in vacuo, correlating data from different imaging modalities, and big data in correlative imaging are also considered. Brings a fresh view to one of the hottest topics within the imaging community: the correlative imaging field Discusses current research and offers expert thoughts on the field’s future developments Presented by internationally-recognized editors and contributors with extensive experience in research and applications Of interest to scientists working in the fields of imaging, structural biology, cell biology, developmental biology, neurobiology, cancer biology, infection and immunity, biomaterials and biomedicine Part of the Wiley–Royal Microscopical Society series Correlative Imaging: Focusing on the Future will appeal to those working in the expanding field of the biosciences, correlative microscopy and related microscopic areas. It will also benefit graduate students working in microscopy, as well as anyone working in the microscopy imaging field in biomedical research.
Recent Progress In Electron Microscopy Of Cells And Tissues
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Author : Eichi Yamada
language : en
Publisher:
Release Date : 1976
Recent Progress In Electron Microscopy Of Cells And Tissues written by Eichi Yamada and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Cytological techniques categories.