Recent Advances In Precision Vaccine Discovery Development
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Recent Advances In Precision Vaccine Discovery Development
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Author : Ofer Levy
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-23
Recent Advances In Precision Vaccine Discovery Development written by Ofer Levy and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-23 with Medical categories.
Topic Editor Jay Evans is the co-founder, President and CEO of Inimmune Corporation. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Natural Product Based Drug Discovery Against Human Parasites
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Author : Archana Singh
language : en
Publisher: Springer Nature
Release Date : 2023-11-27
Natural Product Based Drug Discovery Against Human Parasites written by Archana Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-27 with Science categories.
This book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites. This book is useful for students and researchers of pharmacology, parasitology, zoology and other allied fields.
Identification Risk Stratification And Optimized Management For Lynch Syndrome
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Author : Inge Bernstein
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-03
Identification Risk Stratification And Optimized Management For Lynch Syndrome written by Inge Bernstein and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-03 with Medical categories.
Toward Precision Medicine
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-01-16
Toward Precision Medicine written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-16 with Medical categories.
Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Ecology Of Parasite Vector Interactions
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Author : Willem Takken
language : en
Publisher: Springer
Release Date : 2013-03-15
Ecology Of Parasite Vector Interactions written by Willem Takken and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-15 with Science categories.
Vector-borne diseases continue to be one of the most important determinants affecting human and animal health. Large numbers of people suffer from diseases like malaria, dengue, filariasis and leishmaniasis, especially in the tropics. Whereas these diseases were eradicated from the temperate climate zones, in recent years the rising incidence of 'emerging' vector-borne diseases such as bluetongue, West Nile Virus, Lyme disease, tick-borne encephalitis and the recent outbreaks of chikungunya and dengue in southern Europe provide evidence that these diseases are resilient and can disperse to other regions and continents where before they were not present or relevant. Many tools for the management of vector-borne diseases are currently under pressure because of increasing drug and insecticide resistance, as well as the realization of biological variation of parasites and vectors and their ecosystems. At the same time, progress in our understanding of genetics, immunology, population biology and epidemiology allow for a better understanding of parasite-vector interactions. Here the state-of-the-art of these interactions is being reviewed, and means for using this information for advanced strategies of vector-borne disease control are proposed. This 3rd edition of ECVD aims to provide a rapid overview of recent developments in the field of parasite-vector interactions and how this can be used for more effective and sustainable disease control.
Olfaction In Vector Host Interactions
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Author : Willem Takken
language : en
Publisher: BRILL
Release Date : 2023-09-04
Olfaction In Vector Host Interactions written by Willem Takken and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-04 with Science categories.
This is a multi-authored book with a focus on the role of olfaction (the sense of smell) in the multitude of interactions between arthropods and their blood hosts. Blood-feeding arthropods (mostly insects, ticks and mites) depend on a vertebrate host for survival and reproduction. Their evolutionary success depends on how efficiently they can detect the presence of a host and actively locate it to obtain a blood meal. This is the domain of olfaction, which is perhaps the most important mode of signal exchange between hosts and blood-feeding arthropods that visit them. Important human and animal diseases like malaria, dengue, West Nile virus, bluetongue and trypanosomiasis are transmitted between humans and/or animals as a direct outcome of olfactory responses mediated by host odours. Increased understanding of olfaction and how this governs interactions between arthropods and blood hosts will enable the development of novel strategies to disrupt this behaviour. For example, many species of tsetse fly respond over distance to simple blends of synthetic odours. Combined with traps or insecticide-treated targets, such odour-baited devices can effectively suppress fly populations and thus transmission of sleeping sickness. Such systems still need to be developed for disease-vectoring mosquitoes, flies and ticks, necessitating further knowledge on the chemical basis of interactions with their vertebrate hosts. In 18 peer-reviewed chapters, recognized experts provide a state-of-the-art overview of olfaction in vector-host interactions, from the molecular to population biology level. A wide range of arthropods is discussed, including mosquitoes, black flies, sand flies, tsetse flies, blood-feeding bugs and ticks. Novel ideas, definition of research gaps, and a collection of the most recent studies will be of value to biology students, chemical ecologists, as well as those implementing vector control programmes.
Emerging Pests And Vector Borne Diseases In Europe
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Author : Willem Takken
language : en
Publisher: BRILL
Release Date : 2023-08-28
Emerging Pests And Vector Borne Diseases In Europe written by Willem Takken and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-28 with Technology & Engineering categories.
"This is a multi-authored book concerning the perceived threat and recorded increase of emerging pests and vector-borne diseases affecting man and animals in Europe. Historically, Europe suffered from numerous pests and vector-borne diseases, including yellow fever, malaria, plague and typhus. Introduction of hygienic measures, drugs and vector control caused the disappearance of many of these diseases from Europe. In the (sub)tropics, however, many of these diseases still thrive, causing serious health problems for humans and animals. Increased trade, leading to animal and human movement and climate change cause reason to assume that several of these diseases might become re-established or allow 'new' diseases and pests to be introduced in Europe. The recent outbreaks of bluetongue virus in North-western Europe highlights this concern, requiring an effective surveillance systems for the early detection of pests and vector-borne diseases. In 24 chapters this book provides examples of the most likely pests and diseases affecting man and animals in Europe, with emphasis on ecological factors favouring these diseases and methods for prevention and intervention. The authors are recognized experts in specific fields. All chapters are peer reviewed."
Vaccine Development
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Author : A Krishna Prasad
language : en
Publisher: Royal Society of Chemistry
Release Date : 2022-11-09
Vaccine Development written by A Krishna Prasad and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-09 with Medical categories.
Vaccine development is a complex and time consuming process that differs from the development of conventional pharmaceuticals. Primarily, vaccines are intended for use in healthy individuals as a preventative measure, requiring a long and rigorous process of research and many years of testing and development prior to clinical trials and regulatory approval. The average time for the development of vaccines to clinical is 12 to 15 years. Vaccine Development: From Concept to Clinic is a detailed overview of the development of new vaccines, covering the entire process and addresses all classes of vaccines from a processing, development and regulatory viewpoint. Utilising successful case studies the book will provide insight to the issues scientists face when producing a vaccine, the steps involved and will serve as an ideal reference tool regarding state-of-the-art vaccine development. This book is an ideal companion for any researchers working in vaccine discovery and development or with an interest in the field.
Vaccine Development From Concept To Clinic
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Author : A. Krishna Prasad
language : en
Publisher: Royal Society of Chemistry
Release Date : 2022-11-09
Vaccine Development From Concept To Clinic written by A. Krishna Prasad and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-09 with Medical categories.
Utilising successful case studies Vaccine Development will provide insight to the issues scientists face when producing a vaccine, the steps involved and will serve as an ideal reference tool regarding state-of-the-art vaccine development.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1987
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medicine categories.