Recent Research In Biomedical Aspects Of Chitin And Chitosan


Recent Research In Biomedical Aspects Of Chitin And Chitosan
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Recent Research In Biomedical Aspects Of Chitin And Chitosan


Recent Research In Biomedical Aspects Of Chitin And Chitosan
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Author : Hiroshi Tamura
language : en
Publisher:
Release Date : 2008-01-01

Recent Research In Biomedical Aspects Of Chitin And Chitosan written by Hiroshi Tamura and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-01 with Biomedical materials categories.


Chitin, poly (ß-(1?4)-N-acetyl-d-glucosamine), is a natural polysaccharide of major importance, first identified in 1884. It is the second most abundant natural polymer after cellulose and exists largely in the marine crustacean. Chitin occurs in nature as ordered crystalline microfibrils forming structural components in the exoskeleton of arthropods or in the cell walls of fungi and yeast. The most important derivative of chitin is chitosan, which is obtained by partial N-deacetylation of chitin in the solid state under alkaline conditions (concentrated NaOH) or by enzymatic hydrolysis in the presence of a chitin deacetylase. Because of the semicrystalline morphology of chitin, chitosans obtained by an alkaline reaction have a heterogeneous distribution of acetyl groups along the chains. Studies on chitin and chitosan have been intensified since 1990 because these polysaccharides show excellent biological properties such as biodegradation in the human body, and immunological, antibacterial, and wound-healing activity. In recent studies, especially, chitosan has been found to be a good candidate as a support material for gene delivery, cell culture, and tissue engineering. Therefore, chitin and chitosan are receiving greater attention as novel functional materials. Despite their interesting biological properties, utilization has been scarcely developed. This review book is a comprehensive introduction to the bioscience and biomedical applications of chitin and chitosan. This review book covers the synthesis and biological properties of chitin and chitosan derivatives and their applications in drug delivery, medical and biological fields. This review book also covers almost all the important findings in these fields and explored these results clearly. The main importance of this review book is to know the chemical and biological properties of chitin and chitosan. These broad ranges of topics that are systematically discussed in this review book will be helpful to carry out more innovative researches in chitin and chitosan in the near future. This review book contains seven chapters included with the various topics of current research interest. Chapter 1 is focusing various methods of preparation of water soluble derivatives of chitin and chitosan. Moreover, the potential applications of these derivatives in the various fields such as drug delivery, food, cosmetics, tissue engineering and environmental is also discussed. In Chapter 2 are reviews the various methods of synthesis, properties of the chemically modified chitosans and their applications of the chemically modified chitosans derivatives for controlled drug and non-viral gene delivery. The knowledge of chitosan scaffold preparation and their characterization and biological activities, which are reported in recent literatures, are discussed in Chapter 3. The Chapter 4, the developments of chitin and chitosan interfaces for the applications in biosensors, microarray, cell arrays, micro fluidic devices and bioimaging are focused. The recent research and development of chitin/chitosan based biomaterials for potential application in orthopedic or bone and cartilage tissue engineering is reviewed in the Chapter 5. The chapter 6 is focusing on the various types of chitosan derivatives and their use in various tissue engineering applications namely, skin, bone, cartilage, liver, nerve and blood vessel. In chapter 7 is focusing about the production and properties of chitin and chitosan obtained from crustacean and fungal sources and their applications in medical and biological sectors are discussed. This review book explains that the advantage of chitin and chitosan over the other polysaccharides. As described in this review, the chemical structure of chitin and chitosan allows specific modifications at their reactive sites, without changing the bulk properties. Specific groups can be introduced into their reactive sites to design polymers for selected applications. Since the biological properties of chitin and chitosan are valuable for medical applications, the developments in these filed can be considered as valuable extensions of the use of chitin and its derivatives. I expect that this review book will be helpful to the people, who are interesting in chitin and chitosan research. I warmly thank the authors for their efforts in producing such informed and enlightening exposition on these topics in chitin and chitosan. Finally, I acknowledge the staff of Research Signpost (India) for their patience and assistance.



Chitin And Chitosan


Chitin And Chitosan
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Author : Shameem Hasan
language : en
Publisher: Springer Nature
Release Date : 2022-08-27

Chitin And Chitosan written by Shameem Hasan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-27 with Technology & Engineering categories.


This book reviews work that covers everything from basic chemistry to advanced applications. Chitin and chitosan are used in a plethora of applications from wastewater treatment to prosthetics. After introducing the subject of polysaccharides as a whole, the authors turn to the preparation of chitin and chitosan and the characterization of the latter. The book provides information on chitin chemistry, extraction of chitin, chitosan preparation processes, and the applications of their derivatives in various fields. Among the applications that are included in detail are the adsorption of heavy metals for pollution prevention and clean-up, biosensors, cosmetics, various medical applications from anti-tumor activity to bone tissue engineering, agriculture and food production, and proton exchange membranes for fuel cells. Chitin and Chitosan features: • information on molecular structure, synthesis, properties, and latest research related to chitin and chitosan; • coverage of a wide range of topics from the properties of chitosan to its derivatives and applications; • in-depth information on biomedical applications of chitin and chitosan; and • information that can be applied to other biopolymer processing engineering areas. This book will be of interest to practitioners working in a wide variety of industries for which chitin and chitosan are useful materials, researchers in biosensors and heavy-metal adsorption, and to academic researchers investigating the properties, preparation, and uses of these materials.



Chitin


Chitin
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Author : Eugene Khor
language : en
Publisher: Elsevier
Release Date : 2014-06-12

Chitin written by Eugene Khor and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-12 with Science categories.


The second edition of Chitin underscores the important factors for standardizing chitin processing and characterization. It captures the essential interplay between chitin's assets and limitations as a biomaterial, placing the past promises of chitin in perspective, addressing its present realities and offering insight into what is required to realize chitin's destiny (including its derivative, chitosan) as a biomaterial of the twenty-first century. This book is an ideal guide for both industrialists and researchers with a vested interest in commercializing chitin. An update on the research since 2001 as it pertains to the biomaterials and biomedical applications of chitin and chitosan An expanded discussion on positioning chitin and chitosan for biomedical applications Presents regulatory aspects of chitin and chitosan



Chitin And Chitosan For Regenerative Medicine


Chitin And Chitosan For Regenerative Medicine
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Author : Pradip Kumar Dutta
language : en
Publisher: Springer
Release Date : 2015-09-04

Chitin And Chitosan For Regenerative Medicine written by Pradip Kumar Dutta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-04 with Technology & Engineering categories.


The book is an excellent reference for scientists, researchers and students working in the field of areas of biopolymeric biomaterials, biomedical engineering, therapeutics, tissue engineering and regenerative medicine. The book is divided into two parts: Part I will focus on the tissue engineering and Part II focuses on therapeutics, functionalization and computer-aided techniques. The book consists of 13 chapters contributed by 20 international contributors who are leading experts in the field of biopolymers and its applications. It will focus on the advancements of chitin and chitosan in regenerative medicine. Regenerative medicine in tissue engineering is the process of replacing or regenerating human cells, tissues, or organs to restore or establish normal function. It is an incredibly progressive field of medicine that may, in the near future, help with the shortage of life-saving organs available through donation for transplantation vis-a-vis regenerative medicine focuses on therapeutics, functionalization and computer-aided techniques. It also covers physical and chemical aspects of chitin and chitosan, structural modifications for biomedical applications, chitosan based scaffolds and biomodelling in tissue engineering, nanomedicines and therapeutic applications. With the broad range of applications, the world is waiting for biopolymers to serve as the basis for regenerative medicine and biomedical applications.



Current Research And Developments On Chitin And Chitosan In Biomaterials Science


Current Research And Developments On Chitin And Chitosan In Biomaterials Science
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Author : R. Jayakumar
language : en
Publisher:
Release Date : 2008-01-01

Current Research And Developments On Chitin And Chitosan In Biomaterials Science written by R. Jayakumar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-01 with Biomedical materials categories.


In recent years there have been tremendous advances in the fields of chemistry, physics and biology which have a direct impact on advances in biomaterials science. These advances have contributed significantly to the improvement of modern health care and continue to influence the practice of medicine. A biomaterial is any material, natural or man-made, that comprises whole or part of a living structure or biomedical device which performs, augments, or replaces a natural function. Among the biomaterials, chitin and chitosan have received much attention due to their non-toxicity, biodegradability, biocompatibility and multifunctional properties with applications in biomedical and pharmaceutical sciences. The main driving force behind the development of new applications for chitin and its derivative chitosan lies with the fact that these polysaccharides represent a renewable source of natural biodegradable polymers. Since chitin is the second most abundant natural polymer, academic as well as industrial scientists are faced with a great challenge to find new and practical applications for this material. This book provides an examination of the state of the art, and discusses current research as well as new biomedical applications of chitin and chitosan. Applications of chitin and chitosan will be of interest to industrial personnel involved in bioprocessing as well as bioengineering students, specialists in the biomedical and biopharmaceutical industry, biochemists, food engineers, environmentalists, and microbiologists and biologists who specialize in chitosan technology. The subject matter of the book is divided into nine chapters. Chapter 1 deals with the preparation and physico-chemical properties of amphiphilic derivatives of chitin and chitosan. The potential applications of these derivatives in the fields of controlled drug and gene delivery are discussed in details. Chapter 2 deals with the inhibitory activity of chitosan against bacteria and fungi potentially encountered in foodstuffs and the modes of action as suggested in the literature. Recent approaches, such as enzymatic depolymerization and chemical modifications, developed to improve the bioactivity of chitosan are reported. In addition, the applications of chitosan based products as biopackaging materials in food preservation are explored. In chapter 3, the recent developments and applications of stimuli-responsive materials based on chitosan are discussed. Moreover, different approaches used to prepare chitosan interpenetrating networks are analyzed and the potential of the resultant system for biomedical applications are critically reviewed. Different methods of chitosan deposition onto substrates for tissue engineering, wound dressing, separation membranes, biocompatible and antibacterial coatings, stent coatings, and sensors applications are reported in chapter 4. Chapter 5 of this book deals with the mechanisms involved in the in vitro calcification of chitosan while chapter 6 discusses the role of chitosan and its derivatives as potent adjuvant/delivery systems for mucosal immunization both in human and veterinary medicine. The current research and developments on chitin and chitosan nanoscaffolds for tissue engineering applications and future demands on bio-products are discussed in chapter 7. Chapter 8 reviews the different techniques of chitosan microsphere preparation for the drug delivery applications. In addition, the advantages of using chitosan microsphere as drug carrier are also explored. Recently, considerable works have been directed to develop an ideal scaffold based on polymer/ceramic composite materials. In this context, chitosan/calcium phosphate composite materials would have an importance in bone tissue engineering. The preparation methods, properties and applications of composite scaffolds and cements based on calcium phosphate and chitosan are reported in chapter 9. We hope this book can serve as a comprehensive introduction to researchers in biomaterials science and engineering in general, and can also be used as a graduate level text in related areas. We thank the authors for their excellent contributions to this book and our publishers for their encouragement which motivated us to produce this book. We believe this will make a lasting contribution to the field of biomaterials science.



Chitosan In Biomedical Applications


Chitosan In Biomedical Applications
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Author : Md Saquib Hasnain
language : en
Publisher: Academic Press
Release Date : 2021-12-01

Chitosan In Biomedical Applications written by Md Saquib Hasnain and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-01 with Technology & Engineering categories.


Chitosan in Biomedical Applications provides a thorough insight into the complete chitosan chemistry, collection, chemical modifications, characterization and applications of chitosan in biomedical applications and healthcare fields. Chitosan, a biopolymer of natural origin, has been explored for its variety of applications in biomedical research, medical diagnostic aids and material science. It is the second most abundant natural biopolymer after cellulose, and considered as an excellent excipient because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of chitosan in biomedical applications. The book explores key topics, such as molecular weight, degree of deacetylation, and molecular geometry, along with an emphasis on recent advances in the field written by academic, industry, and clinical researchers. Chitosan in Biomedical Applications will be of interest to those in biomedical fields including the biomaterials and tissue engineering community investigating and developing biomaterials for biomedical applications, particularly graduate students, young faculty and others exploring chitosan-based materials. Provides methodology for the design, development and selection of chitosan in biomedical applications for particular therapeutic applications Includes illustrations demonstrating the mechanism of biological interaction of chitosan Discusses the regulatory aspects and demonstrates the clinical efficacy of chitosan



Chitin And Chitosan Derivatives


Chitin And Chitosan Derivatives
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Author : Se-Kwon Kim
language : en
Publisher: CRC Press
Release Date : 2013-12-04

Chitin And Chitosan Derivatives written by Se-Kwon Kim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-04 with Medical categories.


A natural long-chain polymer, chitin is the main component of the cell walls of fungi, the exoskeletons of arthropods (including crustaceans and insects), the radulas of mollusks, and the beaks and internal shells of cephalopods. However, marine crustacean shells are the primary sources of the chitin derivative chitosan. Chitin and chitosan are useful for various biological and biomedical applications, although they have been limited by poor solubility in the past. Current research focuses on increasing their solubility and bioactivity through molecular modifications. The resulting derivatives are receiving much attention for interesting properties, such as biocompatibility, biodegradability, and nontoxicity, that make them suitable for use in the biomedical field. Chitin and Chitosan Derivatives: Advances in Drug Discovery and Developments presents current research trends in the synthesis of chitin and chitosan derivatives, their biological activities, and their biomedical applications. Part I discusses basic information about the synthesis and characterization of a variety of derivatives, including the preparation of chitin nanofibers. Part II covers chitin and chitosan modifications as the basis for biological applications. It describes antioxidant, anti-inflammatory, anticancer, antiviral, anticoagulant, and antimicrobial activities. Part III addresses chemically modified and composite materials of chitin and chitosan derivatives for biomedical applications, such as tissue engineering, nanomedicine, drug delivery, and wound dressing. A must-have reference for novices and experts in biotechnology, natural products, materials science, nutraceuticals, and biomedical engineering, this book presents a wide range of biological and biomedical applications of chitin and chitosan derivatives for drug discovery and development.



Chitosan Based Biomaterials Volume 1


Chitosan Based Biomaterials Volume 1
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Author : Jessica Amber Jennings
language : en
Publisher: Woodhead Publishing
Release Date : 2016-09-26

Chitosan Based Biomaterials Volume 1 written by Jessica Amber Jennings and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-26 with Technology & Engineering categories.


Chitosan Based Biomaterials: Fundamentals, Volume 1, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book looks at the fundamentals of chitosan-based biomaterials. Contains specific focus on the techniques and technologies needed to develop chitosan for biomedical applications Presents a comprehensive treatment of the fundamentals Provides contributions from leading researchers with extensive experience in chitosan



Chitosan Based Biomaterials Volume 2


Chitosan Based Biomaterials Volume 2
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Author : Jessica Amber Jennings
language : en
Publisher: Woodhead Publishing
Release Date : 2016-09-28

Chitosan Based Biomaterials Volume 2 written by Jessica Amber Jennings and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-28 with Technology & Engineering categories.


Chitosan Based Biomaterials: Tissue Engineering and Therapeutics, Volume 2, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book provides readers with a full coverage of the applications of chitosan-based biomaterials. Presents specific focus on tissue engineering and therapeutics Provides comprehensive treatment of all biomaterial applications of chitosan Contains contributions by leading researchers with extensive experience in the material



Chitin And Chitosan


Chitin And Chitosan
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Author : Gregorio Crini
language : en
Publisher: Academic Press
Release Date : 2022-06-15

Chitin And Chitosan written by Gregorio Crini and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-15 with Business & Economics categories.


Chitin and Chitosan: Discoveries and Applications for Sustainability provides the most comprehensive knowledge on these organic biopolymers which come from the cellular makeup of crustaceans, mollusks and arthropods. This book synthesizes historical information, fundamental properties, industrial applications, and recent discoveries and uses. Written by an international expert on chitin and chitosan sources and uses, the book discusses landmark discoveries and early uses in the research and applications of chitin and chitosan. It then explores the international use of chitin and chitosan as organic solutions across various disciplines such as aquaculture, agriculture, food and beverage industries, cosmetics and medicine. Finally, the book assesses their environmental applications for sustainable solutions, such as wastewater treatments and future chitin and chitosan usage as an organic solution for a more sustainable, green, healthy planet. Offers a comprehensive review of these biopolymers, from their discovery to their use in our daily lives Details the main historical facts on their composition, structure and properties Emphasizes the chemical and biological properties and applications of chitosan Describes key challenges and future trends