Rechtliche Aspekte Der Genom Editierung An Der Menschlichen Keimbahn
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Rechtliche Aspekte Der Genom Editierung An Der Menschlichen Keimbahn
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Author : Jochen Taupitz
language : de
Publisher: Springer-Verlag
Release Date : 2019-11-27
Rechtliche Aspekte Der Genom Editierung An Der Menschlichen Keimbahn written by Jochen Taupitz and has been published by Springer-Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-27 with Law categories.
Das Buch enthält 19 Landesberichte und eine rechtsvergleichende Analyse der rechtlichen Regelungen zum Verfahren der Genom-Editierung an der menschlichen Keimbahn. Es wird herausgearbeitet, welche gemeinsamen Werte die verschiedenen Rechtsordnungen verbinden und welche Unterschiede bestehen. Auf dieser Grundlage wird untersucht, ob eine internationale Regulierung der Thematik möglich ist und wie diese ausgestaltet sein könnte. Zudem soll untersucht werden, in wie weit die Regelungen anderer Länder als Modell für die deutsche Gesetzgebung dienen können.
Genome Editing Interdisziplin Re Technikfolgenabsch Tzung
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Author : Alexander Lang
language : de
Publisher: vdf Hochschulverlag AG
Release Date : 2019
Genome Editing Interdisziplin Re Technikfolgenabsch Tzung written by Alexander Lang and has been published by vdf Hochschulverlag AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Education categories.
Mit den neuesten Methoden der Gentechnik kann das Erbgut mit geringerem Aufwand und höherer Präzision verändert werden als bisher. Die erst seit wenigen Jahren verfügare Technik CRISPR wird in der Forschung bereits rege benutzt und weckt grosse Erwartungen. Solche als Genome Editing (Genom-Editierung) bezeichneten Verfahren eröffnen in der Medizin und der Tier- und Pflanzenzucht neue Möglichkeiten, die mitunter kontrovers diskutiert werden. Bei Pflanzen gibt es erste Anwendungen, aber Unklarheiten in Bezug auf die Akzeptanz durch die Bevölkerung und die Regulierung. In der Medizin könnte die somatische Gentherapie bald öfter eingesetzt werden und die Xenotransplantation rückt näher in den Bereich des Möglichen; es stellen sich jedoch Fragen nach Sicherheit, Finanzierung und Alternativen. Zudem ist die Diskussion um Eingriffe in die menschliche Keimbahn neu entflammt. Gene Drives könnten Organismen in ganzen Ökosystemen verändern – mit ungewissen Folgen. Die interdisziplinäre Studie untersucht Chancen und Risiken des Genome Editings in diesen Bereichen. Sie präsentiert die technisch-naturwissenschaftlichen Grundlagen und analysiert ethische, rechtliche und ökonomische Aspekte.
Rechtliche Herausforderungen Moderner Verfahren Der Intervention In Die Menschliche Keimbahn
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Author : Silvia Deuring
language : de
Publisher: Springer-Verlag
Release Date : 2019-11-29
Rechtliche Herausforderungen Moderner Verfahren Der Intervention In Die Menschliche Keimbahn written by Silvia Deuring and has been published by Springer-Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-29 with Law categories.
Dieses Buch befasst sich mit der rechtlichen Bewertung von modernen Verfahren der Intervention in die menschliche Keimbahn, d.h. von gentechnischen Veränderungen am Menschen, die an die nachfolgenden Generationen weitergegeben werden. Neuartige Methoden wie die CRISPR/Cas9-Technik, der Mitochondrientransfer und die Möglichkeit der Herstellung artifizieller Gameten aus hiPS-Zellen stellen das Recht vor neue Herausforderungen. Insbesondere ist fraglich, ob die aktuell bestehenden Gesetze diese neuen Verfahren noch erfassen oder ob gesetzliche Lücken entstanden sind. Dieses Buch analysiert in diesem Zusammenhang die Rechtslage in Deutschland und Frankreich. Es behandelt dabei sowohl genetische Veränderungen an menschlichen Keimbahnzellen zur Forschung in vitro als auch solche, die in der Geburt von Menschen münden. Zudem wird der Frage nachgegangen, ob das deutsche Verfassungsrecht einer Anwendung dieser Verfahren grundsätzlich entgegensteht oder ob eine gesetzliche Zulassung in der Zukunft unter bestimmten Voraussetzungen möglich wäre. Auf der Grundlage des Rechtsvergleichs sowie der verfassungsrechtlichen Untersuchung formuliert das Buch einen Regelungsvorschlag, sowohl zur Beseitigung aktuell bestehender rechtlicher Lücken und Unklarheiten als auch im Hinblick auf eine (künftige) mögliche Anwendung der Verfahren.
Between Moral Hazard And Legal Uncertainty
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Author : Matthias Braun
language : en
Publisher: Springer VS
Release Date : 2018-11-21
Between Moral Hazard And Legal Uncertainty written by Matthias Braun and has been published by Springer VS this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-21 with Philosophy categories.
Genome Editing Techniques are seen to be at the frontier of current research in the field of emerging biotechnologies. The latest revolutionary development, the so-called CRISPR technology, represents a paradigmatic example of the ambiguity of such techniques and has resulted in an international interdisciplinary debate on whether or not it is necessary to ban the application of this technique by means of a moratorium on its use for human germline modifications, particularly in human embryos in the reproduction process. However, given that other germline engineering techniques like mitochondrial (mt) DNA transfer techniques are already permitted and applied, the question arises what lies at the root of the apparent social unease about the modification of the human germline by Genome Editing Techniques like CRISPR. Against this background, the book seeks to make a substantial contribution to the current debate about a responsible and participatory framework for research on emerging biotechnologies by analysing underlying perceptions, attitudes, arguments and the reasoning on Genome Editing Techniques.
Regulation Of Genome Editing In Human Ips Cells
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Author : Hans-Georg Dederer
language : en
Publisher: Springer Nature
Release Date : 2022-05-23
Regulation Of Genome Editing In Human Ips Cells written by Hans-Georg Dederer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-23 with Law categories.
The book provides a concise overview of currently applicable regulatory frameworks of states which are among the world leaders in research and development (R&D) of cell and gene therapies. Developments in genome editing are expected to lead to new possibilities for the treatment of hereditary diseases in humans. The treatment of such often severe but hitherto uncurable diseases can be based on genome-edited induced pluripotent stem cells (iPS cells). Such treatments constitute combined cell/gene therapies. These therapies need to be governed by a regulatory framework which ensures quality, safety, and efficacy of the relevant therapeutic products. On the other hand, such regulations may retard product approval and impede R&D. Accordingly, national regulations for therapies based on genome-edited iPS cells are an important and, as the case may be, decisive factor for both researchers and industry regarding their decision where to locate their R&D activities. Therefore, regulatory frameworks impact significantly on the competitiveness of states and their economies. This is why a comparative analysis of laws and regulations of different countries matters. Such a comparative legal analysis provides an important insight into regulatory concepts which, in turn, may inspire adjustments of, or amendments to, domestic legal regimes. For this purpose, experts present country reports on France, Germany, Japan, South Korea, Switzerland, and the USA. The reports on France and Germany also refer to the parameters and implications arising from pertinent EU law. This contributed volume is aimed at researchers, but also at, e.g., legal scholars, lawmakers, regulators, and political decision makers.
Ethics Dumping
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Author : Doris Schroeder
language : en
Publisher: Springer
Release Date : 2017-12-04
Ethics Dumping written by Doris Schroeder and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-04 with Philosophy categories.
This open access book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.
Philosophy For Dummies
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Author : Tom Morris
language : en
Publisher: John Wiley & Sons
Release Date : 2011-03-10
Philosophy For Dummies written by Tom Morris and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-10 with Philosophy categories.
Discover how to apply ancient wisdom to your everyday life Philosophy at its best is an activity more than a body of knowledge. In an ancient sense, done right, it is a healing art. It’s intellectual self-defense. It’s a form of therapy. But it’s also much more. Philosophy is map-making for the soul, cartography for the human journey. It’s an important navigational tool for life that too many modern people try to do without. Philosophy For Dummies is for anyone who has ever entertained a question about life and this world. In a conversational tone, the book's author – a modern-day scholar and lecturer – brings the greatest wisdom of the past into the challenges that we face now. This refreshingly different guide explains philosophical fundamentals and explores some of the strangest and deepest questions ever posed to human beings, such as How do we know anything? What does the word good mean? Are we ever really free? Do human beings have souls? Is there life after death? Is there a God? Is happiness really possible in our world? This book is chock full of all those questions you may have long wanted to think about and talk with someone about, but have never had the time or opportunity to tackle head on. Philosophy For Dummies invites you to discuss the issues you find in the guide, share perspectives, and compare thoughts and feelings with someone you respect. You'll find lots of material to mull over with your friends or spouse, including thoughts on When to doubt, and when to doubt our doubts The universal demand for evidence and proof The four dimensions of human experience Arguments for materialism Fear of the process of dying Prayers and small miracles Moral justification for allowing evil The ancient philosopher Socrates (fifth century, B.C.) thought that, when it comes to the Ultimate Questions, we all start off as dummies. But if we are humbly aware of how little we actually know, then we can really begin to learn. Philosophy For Dummies will put you on the path to wising up as you steer through the experience called life.
Redesigning Life
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Author : John Parrington
language : en
Publisher: Oxford University Press
Release Date : 2016
Redesigning Life written by John Parrington and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Science categories.
Rapid developments in the manipulation of genomes, including editing genes with 'molecular scissors' and the synthesizing of new lifeforms look set to transform our future, and perhaps that of life on Earth. John Parrington explains the cutting edge science and its implications.
Human Genome Editing
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-08-13
Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-13 with Medical categories.
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
The Map And The Territory
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Author : Shyam Wuppuluri
language : en
Publisher: Springer
Release Date : 2018-02-13
The Map And The Territory written by Shyam Wuppuluri and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-13 with Science categories.
This volume presents essays by pioneering thinkers including Tyler Burge, Gregory Chaitin, Daniel Dennett, Barry Mazur, Nicholas Humphrey, John Searle and Ian Stewart. Together they illuminate the Map/Territory Distinction that underlies at the foundation of the scientific method, thought and the very reality itself. It is imperative to distinguish Map from the Territory while analyzing any subject but we often mistake map for the territory. Meaning for the Reference. Computational tool for what it computes. Representations are handy and tempting that we often end up committing the category error of over-marrying the representation with what is represented, so much so that the distinction between the former and the latter is lost. This error that has its roots in the pedagogy often generates a plethora of paradoxes/confusions which hinder the proper understanding of the subject. What are wave functions? Fields? Forces? Numbers? Sets? Classes? Operators? Functions? Alphabets and Sentences? Are they a part of our map (theory/representation)? Or do they actually belong to the territory (Reality)? Researcher, like a cartographer, clothes (or creates?) the reality by stitching multitudes of maps that simultaneously co-exist. A simple apple, for example, can be analyzed from several viewpoints beginning with evolution and biology, all the way down its microscopic quantum mechanical components. Is there a reality (or a real apple) out there apart from these maps? How do these various maps interact/intermingle with each other to produce a coherent reality that we interact with? Or do they not? Does our brain uses its own internal maps to facilitate “physicist/mathematician” in us to construct the maps about the external territories in turn? If so, what is the nature of these internal maps? Are there meta-maps? Evolution definitely fences our perception and thereby our ability to construct maps, revealing to us only those aspects beneficial for our survival. But the question is, to what extent? Is there a way out of the metaphorical Platonic cave erected around us by the nature? While “Map is not the territory” as Alfred Korzybski remarked, join us in this journey to know more, while we inquire on the nature and the reality of the maps which try to map the reality out there. The book also includes a foreword by Sir Roger Penrose and an afterword by Dagfinn Follesdal.