Recomb

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Recomb 2004

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Author : Dan Gusfield
language : en
Publisher: Association for Computing Machinery (ACM)
Release Date : 2004

Recomb 2004 written by Dan Gusfield and has been published by Association for Computing Machinery (ACM) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.

Recomb 2003

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Author : Webb Miller
language : en
Publisher:
Release Date : 2003

Recomb 2003 written by Webb Miller and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Computer science categories.

We study haplotype reconstruction under the Mendelian law of inheritance and the minimum recombination principleon pedigree data. We prove that the problem of finding a mini-mum-recombinant haplotype configuration (MRHC) is in general NP-hard. This is the first complexity result concerning the problem to our knowledge. An iterative algorithm based on blocks of consecutive resolved marker loci (called block-extension) is proposed. It is very efficient and can be used for large pedigrees with a large number of markers, especially for those data sets requiring few recombinants (or recombination events). A polynomial-time exact algorithm for haplotype reconstruction without recombinants is also presented. This algorithm first identifies all the necessary constraints based on the Mendelian law and the zero recombinant assumption, and represents them using a system of linear equations over the cyclic group Z2. By using a simple method based on Gaussian elimination, we could obtain all possible feasible haplotype configurations. We have tested the block-extension algorithm on simulated data generated on three pedigree structures. The results show that the algorithm performs very well on both multi-allelic and biallelic data, especially when the number of recombinants is small.

Recombinant Dna Technical Bulletin

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Author :
language : en
Publisher:
Release Date : 1981

Recombinant Dna Technical Bulletin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Genetic engineering categories.

Research In Computational Molecular Biology

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Author : Jian Ma
language : en
Publisher: Springer Nature
Release Date :

Research In Computational Molecular Biology written by Jian Ma and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.

Research In Computational Molecular Biology

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Author : Haixu Tang
language : en
Publisher: Springer Nature
Release Date : 2023-04-02

Research In Computational Molecular Biology written by Haixu Tang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-02 with Computers categories.

This book constitutes the refereed proceedings of the 27th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2023, held in Istanbul, Turkey, during April 16–19, 2023. The 11 regular and 33 short papers presented in this book were carefully reviewed and selected from 188 submissions. The papers report on original research in all areas of computational molecular biology and bioinformatics.

Research In Computational Molecular Biology

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Author : Lenore J. Cowen
language : en
Publisher: Springer
Release Date : 2019-04-15

Research In Computational Molecular Biology written by Lenore J. Cowen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Computers categories.

This book constitutes the proceedings of the 23rd Annual Conference on Research in Computational Molecular Biology, RECOMB 2019, held in Washington, DC, USA, in April 2019. The 17 extended and 20 short abstracts presented were carefully reviewed and selected from 175 submissions. The short abstracts are included in the back matter of the volume. The papers report on original research in all areas of computational molecular biology and bioinformatics.

Combinatorics Of Genome Rearrangements

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Author : Guillaume Fertin
language : en
Publisher: MIT Press
Release Date : 2009

Combinatorics Of Genome Rearrangements written by Guillaume Fertin and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Combinatorial analysis categories.

A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.

Computational Biology Support

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Author :
language : en
Publisher:
Release Date : 2006

Computational Biology Support written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.

This funding was support for student and postdoctoral attendance at the Annual Recomb Conference from 2001 to 2005. The RECOMB Conference series was founded in 1997 to provide a scientific forum for theoretical advances in computational biology and their applications in molecular biology and medicine. The conference series aims at attracting research contributions in all areas of computational molecular biology. Typical, but not exclusive, the topics of interest are: Genomics, Molecular sequence analysis, Recognition of genes and regulatory elements, Molecular evolution, Protein structure, Structural genomics, Gene Expression, Gene Networks, Drug Design, Combinatorial libraries, Computational proteomics, and Structural and functional genomics. The origins of the conference came from the mathematical and computational side of the field, and there remains to be a certain focus on computational advances. However, the effective use of computational techniques to biological innovation is also an important aspect of the conference. The conference had a growing number of attendees, topping 300 in recent years and often exceeding 500. The conference program includes between 30 and 40 contributed papers, that are selected by a international program committee with around 30 experts during a rigorous review process rivaling the editorial procedure for top-rate scientific journals. In previous years papers selection has been made from up to 130--200 submissions from well over a dozen countries. 10-page extended abstracts of the contributed papers are collected in a volume published by ACM Press and Springer, and are available at the conference. Full versions of a selection of the papers are published annually in a special issue of the Journal of Computational Biology devoted to the RECOMB Conference. A further point in the program is a lively poster session. From 120-300 posters have been presented each year at RECOMB 2000. One of the highlights of each RECOMB conference is a collection of nine keynotes awarded to researchers of highest international esteem who are asked to inform the community about landmark advances in computational and experimental research and inject new directions into the field of computational molecular biology. This includes the following conference events: Next we present a list of the names of the students and postdocs supported. Those supported either presented a paper (10 in 2001, 6 in 2002, 7 in 2003, 14 in 2004, and 20 in 2006) or were they presenter of a poster. This support was vital to the quality and success of the Conference. At the conclusion we give the publication details of the relevant Recomb proceedings.

Comparative Genomics

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Author : Celine Scornavacca
language : en
Publisher: Springer
Release Date : 2024-05-16

Comparative Genomics written by Celine Scornavacca and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-16 with Mathematics categories.

This book constitutes the proceedings of the 21st International Conference on Comparative Genomics, RECOMB-CG 2024, which was held in Boston, MA, USA, during April 27–28, 2024. The 13 full papers presented in this book were carefully reviewed and selected from 21 submissions. The papers are divided into the following topical sections: phylogenetic networks; homology and phylogenetic reconstruction; tools for evolution reconstruction; genome rearrangements; and genome evolution.

Calbiochem General Catalog

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Author :
language : en
Publisher:
Release Date : 2002

Calbiochem General Catalog written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.