Redox Biochemistry
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Redox Biochemistry
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Author : Ruma Banerjee
language : en
Publisher: John Wiley & Sons
Release Date : 2007-12-04
Redox Biochemistry written by Ruma Banerjee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-04 with Science categories.
This is the premier, single-source reference on redox biochemistry, a rapidly emerging field. This reference presents the basic principles and includes detailed chapters focusing on various aspects of five primary areas of redox biochemistry: antioxidant molecules and redox cofactors; antioxidant enzymes; redox regulation of physiological processes; pathological processes related to redox; and specialized methods. This is a go-to resource for professionals in pharmaceuticals, medicine, immunology, nutrition, and environmental fields and an excellent text for upper-level students.
Redox Chemistry And Biology Of Thiols
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Author : Beatriz Alvarez
language : en
Publisher: Academic Press
Release Date : 2022-05-25
Redox Chemistry And Biology Of Thiols written by Beatriz Alvarez and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-25 with Science categories.
Redox Chemistry and Biology of Thiols offers an applied, comprehensive overview of redox chemistry and biology of thiol-dependent processes. Running from basic biology and chemistry of redox phenomena to research methods and highlighting recently identified roles of thiols across cellular and bodily systems, this book draws upon a range of disciplines to illuminate new research directions, new applications of thiol studies, and clinical translation. Sections cover thiol oxidizing species, thiol reactivity and modifications, thioredoxin, glutaredoxin, glutathione, peroxidases, thiol repair enzymes, thiol oxidative signaling, disulfide bond formation, thiol-based redox biosensors, cysteine and hydrogen sulfide metabolism, iron-sulfur cluster biogenesis, thiols in chloroplasts, blood thiols, sugar and polyamine thiols in pathogenic organisms, redox medicine (therapeutic applications of thiols and drug development), as well as methods and bioinformatics tools. Runs from basic thiol biology and chemistry to applications and clinical translation Provides methods and protocols that will power new research across biomedicine, cell biology, plant biology, drug development, and protein folding and modulation Includes chapter contributions from international leaders in the field
Redox Active Therapeutics
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Author : Ines Batinić-Haberle
language : en
Publisher: Springer
Release Date : 2016-10-13
Redox Active Therapeutics written by Ines Batinić-Haberle and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-13 with Science categories.
This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.
Redox Signaling And Regulation In Biology And Medicine
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Author : Claus Jacob
language : en
Publisher: John Wiley & Sons
Release Date : 2009-05-06
Redox Signaling And Regulation In Biology And Medicine written by Claus Jacob and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-06 with Science categories.
This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way. Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.
Hydrogen Sulfide In Redox Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-03-03
Hydrogen Sulfide In Redox Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-03 with Science categories.
These new volumes of Methods in Enzymology (554 and 555) on Hydrogen Sulfide Signaling continue the legacy established by previous volumes on another gasotransmitter, nitric oxide (Methods in Enzymology volumes 359, 396, 440, and 441), with quality chapters authored by leaders in the field of hydrogen sulfide research. These volumes of Methods in Enzymology were designed as a compendium for hydrogen sulfide detection methods, the pharmacological activity of hydrogen sulfide donors, the redox biochemistry of hydrogen sulfide and its metabolism in mammalian tissues, the mechanisms inherent in hydrogen sulfide cell signaling and transcriptional pathways, and cell signaling in specific systems, such as cardiovascular and nervous system as well as its function in inflammatory responses. Two chapters are also devoted to hydrogen sulfide in plants and a newcomer, molecular hydrogen, its function as a novel antioxidant. Continues the legacy of this premier serial with quality chapters on hydrogen sulfide research authored by leaders in the field Covers conventional and new hydrogen sulfide detection methods Covers the pharmacological activity of hydrogen sulfide donors Contains chapters on important topics on hydrogen sulfide modulation of cell signaling and transcriptional pathways, and the role of hydrogen sulfide in the cardiovascular and nervous systems and in inflammation
Biochemistry Of Redox Reactions
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Author : Bernard Testa
language : en
Publisher: Academic Press
Release Date : 1995
Biochemistry Of Redox Reactions written by Bernard Testa and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medical categories.
Surpassing the 1976 book by Testa and Jenner, Drug Metabolism: Chemical and Biochemical Aspects (Dekker), this informative, up-to-date text includes the following features, unavailable elsewhere: First in a set of books to provide a comprehensive coverage of drug metabolism; Opening chapter provides a general introduction to the complete set of books; Other chapters cover reaction mechanisms, catalytic cycles, regio- and stereoselectivities, types of substrates, reactivity of intermediates, and drug-enzyme interactions; Extensive detailed diagrams of reaction pathways and chemical structures * First in a set of books providing a comprehensive coverage of drug metabolism * Opening chapter provides a general introduction to the complete set of books * Other chapters cover reaction mechanisms, catalytic cycles, regio and stereoselectivities, types of substrates, reactivity of intermediates and drug-enzyme interactions * Extensive detailed diagrams of reaction pathways and chemical structures
Redox Chemistry And Interfacial Behavior Of Biological Molecules
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Author : Glenn Dryhurst
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Redox Chemistry And Interfacial Behavior Of Biological Molecules written by Glenn Dryhurst and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The papers in this book were presented at the Third International Symposium on Redox Mechanisms and Interfacial Properties of Molecules of Biological Importance held in Honolulu, Hawaii between October 19-23, 1987. This Symposium was held as part of the 172nd Meeting of The Electrochemical Society which was cosponsored by The Electrochemical Society of Japan with the cooperation of The Japan Society of Applied Physics. The aim of the Symposium was to bring together a group of electrochemists and bio-medical scientists with interests in electrochemistry from around the world to present their most current research results and/or to present up-to-date reviews of current areas of research activity. It is quite clear from the diversity of topics covered in the various papers that electrochemistry and electrochemical techniques and principles have much to contribute to our under standing of many important biochemical phenomena. For example, electrochemical studies are providing important insights into the redox properties of biomolecules ranging from relatively small organic molecules such as indoleamine neurotransmitters to very large organic/organometallic molecules which include various redox enzymes or model enzyme systems. Many of the most powerful analytical techniques are now being coupled to electrodes to monitor potential-controlled behaviors of bio logical molecules at charged interfaces. Electrochemical techniques are now being developed which permit extraordinarily small electrodes to be inserted into single cells to monitor electroactive biomolecules. Other microelectrodes are being employed to control cell growth and to manipulate single cells.
Cellular Implications Of Redox Signaling
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Author : Carlos Gitler
language : en
Publisher: World Scientific
Release Date : 2003-07-30
Cellular Implications Of Redox Signaling written by Carlos Gitler and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-30 with Science categories.
Redox regulation, like phosphorylation, is a covalent regulatory system that controls many of the normal cellular functions of all living cells and organisms. In addition, it controls how cells respond to stress involving oxidants and free radicals, which underlie many degenerative diseases. This area is undergoing a transition from general knowledge to specific description of the components and mechanisms involved. This invaluable book provides a timely basic description of a field whose relevance to cell biology and degenerative diseases is of the utmost importance. It describes the state of the art, lays the foundations for understanding the reactions involved, and presents the prospects for future developments. It can serve as a basic text for any undergraduate or graduate course that deals with redox regulation, oxidative stress and free radicals under normal and pathological conditions in bacterial, plant and animal cells. Contents:The Role of Thioredoxin and Glutaredoxin Systems in Disulfide Reduction and Thiol Redox ControlSelenocysteine Insertion and Reactivity: Mammalian Thioredoxin Reductases in Relation to Cellular Redox SignalingIron–Sulfur Proteins: Properties and FunctionsThe Ferredoxin Ferredoxin/Thioredoxin Thioredoxin System. A Light-Dependent Redox Regulatory System in Oxygenic Photosynthetic CellsThioredoxin and Redox Regulation: Beginnings in Photosynthesis Lead to a Role in Germination and Improvement of CerealsThe Role of Thioredoxin in Regulatory Cellular FunctionsProtein S-Thiolation, S-Nitrosylation, and Irreversible Sulfhydryl Oxidation: Roles in Redox RegulationRadical Scavenging by Thiols: Biological Significance and Implications for Redox Signaling and Antioxidant DefenseAscorbate and Glutathione Metabolism in Plants: H2O2-Processing and SignalingDisulfide Bond Formation in the Periplasm and Cytoplasm of Escherichia ColiThe Thiol Redox Paradox in the Requirement for Disulfide Isomerization in the Eukaryotic Endoplasmic ReticulumMechanisms Controlling Redox Balance in Cells. Inhibition of Thioredoxin and of Thioredoxin ReductaseRegulatory Disulfides Controlling Transcription Factor Activity in the Bacterial and Yeast Responses to Oxidative StressRedox Signaling During Light-Regulated Translation in ChloroplastsRegulation of mRNA Translation and Stability in Iron Metabolism: Is There a Redox Switch?Redox Flow as an Instrument for Gene RegulationThe Permeability Transition Pore as Source and Target of Oxidative Stress Readership: Researchers and graduate students in the life sciences, especially biochemistry.
Redox Proteins In Supercomplexes And Signalosomes
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Author : Ricardo O. Louro
language : en
Publisher: CRC Press
Release Date : 2016-03-09
Redox Proteins In Supercomplexes And Signalosomes written by Ricardo O. Louro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-09 with Medical categories.
Get Insight on the Function of Supercomplexes in Biological Systems Redox Proteins in Supercomplexes and Signalosomes is one of the first books to explore the key role played by redox proteins and their interaction network in a wide range of essential cellular processes in all domains of life. The book explains how the mitochondrial respiratory chain is dynamically organized in supercomplexes even under physiological conditions. It also addresses the impact of supercomplex assembly on mitochondrial morphology, physiology, and biogenesis to shed light on the molecular mechanisms of pathological situations, including aging. Discover the Connection between Bioenergetic Supercomplexes and Signalosomes Compiling state-of-the-art research from leading practitioners in the field, this book gives you guidance on dealing with these biological systems in your investigations. The book shows that supercomplexes and signalosomes provide the link between reductive and systems biology, which enables us to understand how the molecular properties of individual macromolecular components trigger cellular function.
Oxidative Stress And Redox Regulation
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Author : Ursula Jakob
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-15
Oxidative Stress And Redox Regulation written by Ursula Jakob and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-15 with Science categories.
Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.