Redox Regulation Of Cell Signaling And Its Clinical Application
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Redox Regulation Of Cell Signaling And Its Clinical Application
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Author : Junji Yodoi
language : en
Publisher: CRC Press
Release Date : 1999-03-29
Redox Regulation Of Cell Signaling And Its Clinical Application written by Junji Yodoi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-03-29 with Medical categories.
Presents recent developments in the rapidly expanding field of redox regulation research. The book examines insights into intracellular communication and new techniques for diagnosing and treating diseases associated with oxidation and reduction. It focuses on important cellular mechanisms, such as redox reactions related to thioredoxin (TRX)/adult
Redox Regulation Of Differentiation And De Differentiation
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Author : Carsten Berndt
language : en
Publisher: CRC Press
Release Date : 2021-08-26
Redox Regulation Of Differentiation And De Differentiation written by Carsten Berndt and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-26 with Science categories.
Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox modifications are established as important regulatory events in cellular functions including differentiation and development. Redox modifications of single cysteines regulate differentiation of stem cells, formation of functioning organs, and de-differentiation such as formation of cancer cells. Current cancer therapy is based on redox events as well and regeneration often reactivates developmental pathways. Understanding differentiation and de-differentiation on a molecular level is therefore a prerequisite for the continuing development of new medical therapies. This book summarizes the roles of redox regulation in development by bringing together different concepts and comparing similarities and differences between various cell types and species. An international team of contributors presents several new aspects of redox-regulated differentiation and de-differentiation, including aspects of redox medicine. Key Features Provides the first summary on this important topic Reviews redox-dependent development of model organisms and single organs Highlights the redox-regulated pathways important for differentiation processes Illustrates the potential of redox medicine Combines state-of-the-art knowledge in differentiation/development, aging/longevity, and repair/regeneration Written by leading experts in the field Related Titles Ayyanathan, K., ed. Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer (ISBN 978-1-77188-067-1) Clarke, M. & J. Frampton. Stem Cells: Biology and Application (ISBN 9780-8153-4511-4) Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Wong, E., ed. Autophagy and Signaling (ISBN 978-0-367-65772-7)
Redox Regulation And Therapeutic Approaches In Cancer
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Author : Mohinder Pal Bansal
language : en
Publisher: Springer Nature
Release Date :
Redox Regulation And Therapeutic Approaches In Cancer written by Mohinder Pal Bansal and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Redox Signaling And Regulation In Biology And Medicine
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Author : Claus Jacob
language : en
Publisher: John Wiley & Sons
Release Date : 2009-05-06
Redox Signaling And Regulation In Biology And Medicine written by Claus Jacob and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-06 with Science categories.
This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way. Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.
Redox Regulation Of Cell Signaling And Its Clinical Application
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Author : Junji Yodoi
language : en
Publisher: CRC Press
Release Date : 1999-03-29
Redox Regulation Of Cell Signaling And Its Clinical Application written by Junji Yodoi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-03-29 with Science categories.
Presents recent developments in the rapidly expanding field of redox regulation research. The book examines insights into intracellular communication and new techniques for diagnosing and treating diseases associated with oxidation and reduction. It focuses on important cellular mechanisms, such as redox reactions related to thioredoxin (TRX)/adult T-cell leukemia-derived factor (ADF).
Oxidative Stress And Redox Regulation
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Author : Ursula Jakob
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-15
Oxidative Stress And Redox Regulation written by Ursula Jakob and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-15 with Science categories.
Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
Cellular Implications Of Redox Signaling
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Author : Carlos Gitler
language : en
Publisher: World Scientific
Release Date : 2003-07-30
Cellular Implications Of Redox Signaling written by Carlos Gitler and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-30 with Science categories.
Redox regulation, like phosphorylation, is a covalent regulatory system that controls many of the normal cellular functions of all living cells and organisms. In addition, it controls how cells respond to stress involving oxidants and free radicals, which underlie many degenerative diseases. This area is undergoing a transition from general knowledge to specific description of the components and mechanisms involved. This invaluable book provides a timely basic description of a field whose relevance to cell biology and degenerative diseases is of the utmost importance. It describes the state of the art, lays the foundations for understanding the reactions involved, and presents the prospects for future developments. It can serve as a basic text for any undergraduate or graduate course that deals with redox regulation, oxidative stress and free radicals under normal and pathological conditions in bacterial, plant and animal cells. Contents:The Role of Thioredoxin and Glutaredoxin Systems in Disulfide Reduction and Thiol Redox ControlSelenocysteine Insertion and Reactivity: Mammalian Thioredoxin Reductases in Relation to Cellular Redox SignalingIron–Sulfur Proteins: Properties and FunctionsThe Ferredoxin Ferredoxin/Thioredoxin Thioredoxin System. A Light-Dependent Redox Regulatory System in Oxygenic Photosynthetic CellsThioredoxin and Redox Regulation: Beginnings in Photosynthesis Lead to a Role in Germination and Improvement of CerealsThe Role of Thioredoxin in Regulatory Cellular FunctionsProtein S-Thiolation, S-Nitrosylation, and Irreversible Sulfhydryl Oxidation: Roles in Redox RegulationRadical Scavenging by Thiols: Biological Significance and Implications for Redox Signaling and Antioxidant DefenseAscorbate and Glutathione Metabolism in Plants: H2O2-Processing and SignalingDisulfide Bond Formation in the Periplasm and Cytoplasm of Escherichia ColiThe Thiol Redox Paradox in the Requirement for Disulfide Isomerization in the Eukaryotic Endoplasmic ReticulumMechanisms Controlling Redox Balance in Cells. Inhibition of Thioredoxin and of Thioredoxin ReductaseRegulatory Disulfides Controlling Transcription Factor Activity in the Bacterial and Yeast Responses to Oxidative StressRedox Signaling During Light-Regulated Translation in ChloroplastsRegulation of mRNA Translation and Stability in Iron Metabolism: Is There a Redox Switch?Redox Flow as an Instrument for Gene RegulationThe Permeability Transition Pore as Source and Target of Oxidative Stress Readership: Researchers and graduate students in the life sciences, especially biochemistry.
Chemical Probes In Biology
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Author : Manfred P. Schneider
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chemical Probes In Biology written by Manfred P. Schneider and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This NATO Advanced Study Institute (co-sponsored by FEBS and INTAS) under the title "Chemical Probes in Biology" was designed to summarize and disseminate recent expert knowledge regarding a deeper understanding ofbiological phenomena on a molecular level. Such scientific activities -frequently termed Bio-organic Chemistry or Chemical Biology are constituting a highly interdisciplinary branch of chemistry beyond the traditional ways in which chemists and biologists have been working in the past. Thus, on this occasion we were bringing together senior experts from the disciplines of Chemistry and Biology in order to amalgamate their diverse yet basically common interests in this area. Ultimate goal was - next to an exchange of information between the two scientific cultures - the communication ofexciting possibilities in interdisciplinary research to the young scientists present. The meeting was held in the Anargyros and Korgialenios School on the Island ofSpeteses, Greece from 18-30 August 2002. The ASI was attended by a total of 91 scholars from 23 different countries. A group of 27 speakers presented a series of 34 highly stimulating, informative and educational lectures covering a broad range of topics relevant to the general theme ofthis meeting: Science at the InteifaceofChemistry, Biology and Medicine. The lectures were complemented by a total of 89 posters presented by the young scholars and a series of short lectures derived thereof This was clearly one ofthe highlites of the meeting creating a lively atmosphere of interaction and intellectual creativity - typical phenomena for the whole meeting.
Nutrients And Cell Signaling
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Author : Janos Zempleni
language : en
Publisher: CRC Press
Release Date : 2005-04-04
Nutrients And Cell Signaling written by Janos Zempleni and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-04 with Medical categories.
Cell signaling is at the core of most biological processes from the simplest to the most complex. In addition to unicellular organisms possessing the essential ability to receive inputs with regard to nutrient availability and noxious stimuli, the cells in multicellular organisms require signaling from adjacent, as well as distant cells to maintain
Dietary Modulation Of Cell Signaling Pathways
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Author : Zigang Dong
language : en
Publisher: CRC Press
Release Date : 2008-09-26
Dietary Modulation Of Cell Signaling Pathways written by Zigang Dong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-26 with Medical categories.
A consequence of rapid progress in the science of nutrigenomics and nutrigenetics is the substantial accumulation of data covering nutrienal modulation of gene expression at the cellular and subcellular levels. Current research is increasingly focused on the role of nutrition and diet in modifying oxidative damage in the progression of disease. Die