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Reducing Adverse Effects Of Cancer Immunotherapy


Reducing Adverse Effects Of Cancer Immunotherapy
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Reducing Adverse Effects Of Cancer Immunotherapy


Reducing Adverse Effects Of Cancer Immunotherapy
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Author : Daniele Maria-Ferreira
language : en
Publisher: Frontiers Media SA
Release Date : 2024-02-13

Reducing Adverse Effects Of Cancer Immunotherapy written by Daniele Maria-Ferreira and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-13 with Medical categories.


Chemotherapy and/or radiotherapy remain the main treatment options for most cancers. However, cancer treatment is associated with numerous adverse effects, including fatigue, stress, hair loss, pain, nausea, vomiting, anemia, altered immune system, oral and intestinal mucositis, which significantly affect patients' quality of life. In addition, the adverse effects may be associated with additional costs, morbidity, and mortality that affect various aspects of the patient's life, including physical health and emotional state. The management and reduction of adverse effects are extremely important and complex and are primarily aimed at providing comfort to the patient during chemotherapy treatment. In addition, it is important to note that in some cases, the severity of side effects associated with cancer treatment may result in the need to reduce the dose, which in turn may be associated with a reduction in the therapeutic efficacy. In view of this, the identification of new options aimed at alleviating the side effects and increasing the tolerability of chemotherapy is necessary to ensure the quality of life of cancer patients.



Adverse Effects Of Cancer Chemotherapy Anything New To Improve Tolerance And Reduce Sequelae


Adverse Effects Of Cancer Chemotherapy Anything New To Improve Tolerance And Reduce Sequelae
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Author : Kulmira Nurgali
language : en
Publisher: Frontiers Media SA
Release Date : 2018-06-12

Adverse Effects Of Cancer Chemotherapy Anything New To Improve Tolerance And Reduce Sequelae written by Kulmira Nurgali and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-12 with categories.


Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.



The Basics Of Cancer Immunotherapy


The Basics Of Cancer Immunotherapy
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Author : Haidong Dong
language : en
Publisher: Springer
Release Date : 2018-01-05

The Basics Of Cancer Immunotherapy written by Haidong Dong and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-05 with Medical categories.


This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring and side-effects different from those of traditional cancer therapy. Especially novel are the side effects of cancer immunotherapy, necessitating greater awareness for both patients and physicians in order to minimize complications of therapy. The patient-friendly, concise, easy-to-understand, and up-to-date knowledge presented in this book will inform patients about the benefits and risks of cancer immunotherapy, and help them and their care providers to understand how immunotherapy would control their unique disease. Researchers and academic professionals in the field of cancer immunotherapy will also find clear and useful information to help them communicate with patients or address unresolved problems. Some key features of the book are: Expertise. All editors and authors are scientists and oncologists specializing in cancer immunotherapy, and are involved in scientific discovery from the early stage of immune-checkpoint inhibitors to today’s daily patient care. Their insights, expertise and experience guarantee the high quality and authority in the science, medicine and practice of cancer immunotherapy. Patient-friendly. This book is written for cancer patients in order to meet their needs when considering immunotherapy. As an educational tool, this book will help the reader balance the risks and benefits based on both science and clinical facts, and therefore to make the best choice in receiving or withdrawing from immunotherapy. Disease Specificity. Cancer is a complicated disease involving multiple stages and pathology. Its response to immunotherapy is individualized and varies depending on cancer types. The authors’ expertise in treating different types of cancers, including melanoma, lung, kidney, bladder, and lymphoma, provides disease-specific insights in applying immunotherapy to each disease.



A Review Of Imaging Of Adverse Events Related To Cancer Immunotherapy Treatments


A Review Of Imaging Of Adverse Events Related To Cancer Immunotherapy Treatments
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Author : Ren Yuan
language : en
Publisher:
Release Date : 2017

A Review Of Imaging Of Adverse Events Related To Cancer Immunotherapy Treatments written by Ren Yuan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.


Learning Objectives:1. To review the mechanisms and potential side effects of immunotherapy agents.2. To review the role of imaging in assessing the potential side effects.3. To review the imaging findings of associated adverse events. Background:Immunotherapy is emerging as an effective tool in the fight against cancer. Using either a passive or active mechanism, immunotherapy aims to boost the immune system and aid a more effective response against tumour cells.In doing this, potential complications can occur secondary to associated autoimmune or inflammatory responses and can affect multiple systems of the patient inclusive of respiratory, endocrine, gastrointestinal and musculoskeletal. Radiologist awareness of the potential complications is important to prevent misdiagnosis of disease progression, allow appropriate imaging to be performed where required in the acute setting and to aid early detection in the elective follow up setting. By detecting the potential adverse events early, treatment can be modified to reduce the severity and related morbidity.Using a variety of imaging modalities inclusive of X-ray, Computed Tomography, MRI and PET imaging, we aim to highlight the potential adverse events associated with immunotherapy treatments at our centre. Conclusion:Immunotherapy treatments can lead to potential multi-systemic adverse events. Radiologist awareness of these may lead to early diagnosis and reduced associated morbidities.



Policy Issues In The Clinical Development And Use Of Immunotherapy For Cancer Treatment


Policy Issues In The Clinical Development And Use Of Immunotherapy For Cancer Treatment
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2016-12-10

Policy Issues In The Clinical Development And Use Of Immunotherapy For Cancer Treatment written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-10 with Medical categories.


Immunotherapy is a form of cancer therapy that harnesses the body's immune system to destroy cancer cells. In recent years, immunotherapies have been developed for several cancers, including advanced melanoma, lung cancer, and kidney cancer. In some patients with metastatic cancers who have not responded well to other treatments, immunotherapy treatment has resulted in complete and durable responses. Given these promising findings, it is hoped that continued immunotherapy research and development will produce better cancer treatments that improve patient outcomes. With this promise, however, there is also recognition that the clinical and biological landscape for immunotherapies is novel and not yet well understood. For example, adverse events with immunotherapy treatment are quite different from those experienced with other types of cancer therapy. Similarly, immunotherapy dosing, therapeutic responses, and response time lines are also markedly different from other cancer therapies. To examine these challenges and explore strategies to overcome them, the National Academies of Sciences, Engineering, and Medicine held a workshop in February and March of 2016. This report summarizes the presentations and discussions from the workshop.



Adverse Effects Of Cancer Chemotherapy Anything New To Improve Tolerance And Reduce Sequelae


Adverse Effects Of Cancer Chemotherapy Anything New To Improve Tolerance And Reduce Sequelae
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Author :
language : en
Publisher:
Release Date : 2018

Adverse Effects Of Cancer Chemotherapy Anything New To Improve Tolerance And Reduce Sequelae written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.


Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.



Understanding Cancer Pain


Understanding Cancer Pain
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Author :
language : en
Publisher:
Release Date : 2000

Understanding Cancer Pain written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Cancer categories.




Stereotactic Body Radiation Therapy


Stereotactic Body Radiation Therapy
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Author : Simon S. Lo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-08-28

Stereotactic Body Radiation Therapy written by Simon S. Lo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-28 with Medical categories.


Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.



Handbook Of Cancer Treatment Related Symptoms And Toxicities


Handbook Of Cancer Treatment Related Symptoms And Toxicities
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Author : Vamsidhar Velcheti
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-01-28

Handbook Of Cancer Treatment Related Symptoms And Toxicities written by Vamsidhar Velcheti and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-28 with Medical categories.


Early recognition and management of adverse effects of cancer treatments are essential for optimal care of patients with cancer, and drastically different approaches are required for different physiologic reactions. Handbook of Cancer Treatment-Related Symptoms and Toxicities is a focused, one-stop resource that enables clinicians to quickly find up-to-date, reliable information needed at the point of care. The high-yield approach prioritizes the most common toxicities associated with cancer treatment, and concise, templated chapters offer fast access to information needed in day-to-day practice. Presents a user-friendly overview of cancer treatment-related symptoms and toxicities management in a practical, easy-to-use format, allowing you to quickly find information in one convenient, concise resource. Covers systemic and radiation therapies, including chemotherapy, immunotherapy, targeted therapies, and radiation therapy, detailing symptoms of each toxicity to confirm your diagnosis. Overviews pharmacologic and non-pharmacologic approaches to symptom management. Offers recommendations for mitigating toxicities in high-risk patients. Discusses key topics such as management of infusion reactions, when the need for biopsy is warranted, and the unique challenges posed by novel immunotherapies.



Oncoimmunology


Oncoimmunology
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Author : Laurence Zitvogel
language : en
Publisher: Springer
Release Date : 2017-12-13

Oncoimmunology written by Laurence Zitvogel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-13 with Medical categories.


In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.