Regenerative Engineering And Developmental Biology
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Regenerative Engineering And Developmental Biology
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Author : David M. Gardiner
language : en
Publisher: CRC Press
Release Date : 2017-08-21
Regenerative Engineering And Developmental Biology written by David M. Gardiner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-21 with Medical categories.
Regenerative Engineering and Developmental Biology: Principles and Applications examines cutting-edge developments in the field of regenerative engineering. Specific attention is given to activities that embrace the importance of integrating developmental biology and tissue engineering, and how this can move beyond repairing damage to body parts to instead regenerate tissues and organs. The text furthermore focusses on the five legs of the field of regenerative engineering, including: materials, developmental biology, stem cells, physics, and clinical translation. This book was written by leading developmental biologists; each chapter examines the processes that these biologists study and how they can be advanced by using the tools available in tissue engineering/biomaterials. Individual chapters are complete with concluding remarks and thoughts on the future of regenerative engineering. A list of references is also provided to aid the reader with further research. Ultimately, this book achieves two goals. The first encourages the biomedical community to think about how inducing regeneration is an engineering problem. The second goal highlights the discoveries with animal regeneration and how these processes can be engineered to regenerate body parts. Regenerative Engineering and Developmental Biology: Principles and Applications was written with undergraduate and graduate-level biomedical engineering students and biomedical professionals in mind.
Regenerative Engineering And Developmental Biology
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Author : David M. Gardiner
language : en
Publisher:
Release Date : 2017
Regenerative Engineering And Developmental Biology written by David M. Gardiner and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with HEALTH & FITNESS categories.
"This cutting-edge comprehensive reference work details the technologies related to cell structure in the regeneration of tissue and organs. The focus of the first few chapters is related to what cells do (proliferation, migration, and differentiation/dedifferentiation), leading to the production of a population of regeneration-competent cells. The book then covers the information that tells cells where to go and what to make. This is the regeneration blueprint that tells the cells how to remake patterns and restore functions."--Provided by publisher.
Stem Cells Regenerative Medicine
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Author : Krishnarao Appasani
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-01
Stem Cells Regenerative Medicine written by Krishnarao Appasani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-01 with Science categories.
Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.
Exploring Sources Of Variability Related To The Clinical Translation Of Regenerative Engineering Products
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2019-07-19
Exploring Sources Of Variability Related To The Clinical Translation Of Regenerative Engineering Products written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-19 with Medical categories.
The emerging multidisciplinary field of regenerative engineering is devoted to the repair, regeneration, and replacement of damaged tissues or organs in the body. To accomplish this it uses a combination of principles and technologies from disciplines such as advanced materials science, developmental and stem cell biology, immunology, physics, and clinical translation. The term "regenerative engineering" reflects a new understanding of the use of tissue engineering for regeneration and also the growing number of research and product development efforts that incorporate elements from a variety of fields. Because regenerative engineered therapies rely on live cells and scaffolds, there are inherent challenges in quality control arising from variability in source and final products. Furthermore, each patient recipient, tissue donor, and product application is unique, meaning that the field faces complexities in the development of safe and effective new products and therapies which are not faced by developers of more conventional therapies. Understanding the many sources of variability can help reduce this variability and ensure consistent results. The Forum on Regenerative Medicine hosted a public workshop on October 18, 2018, in Washington, DC, to explore the various factors that must be taken into account in order to develop successful regenerative engineering products. Invited speakers and participants discussed factors and sources of variability in the development and clinical application of regenerative engineering products, characteristics of high-quality products, and how different clinical needs, models, and contexts can inform the development of a product to improve patient outcomes. This publication summarizes the presentation and discussion of the workshop.
3d Bioprinting In Regenerative Engineering
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Author : Ali Khademhosseini
language : en
Publisher: CRC Press
Release Date : 2018-04-17
3d Bioprinting In Regenerative Engineering written by Ali Khademhosseini and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-17 with Technology & Engineering categories.
Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications
Developmental Biology And Musculoskeletal Tissue Engineering
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Author : Martin J. Stoddart
language : en
Publisher: Academic Press
Release Date : 2018-04-24
Developmental Biology And Musculoskeletal Tissue Engineering written by Martin J. Stoddart and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-24 with Science categories.
Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair
Organ Regeneration Based On Developmental Biology
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Author : Takashi Tsuji
language : en
Publisher: Springer
Release Date : 2017-03-30
Organ Regeneration Based On Developmental Biology written by Takashi Tsuji and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-30 with Science categories.
This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerative therapy, is to develop fully functioning bioengineered 3D organs that can replace lost or damaged organs following disease, injury, or aging. Next-generation regenerative therapy will consist of organ-replacement regenerative therapy, which aims to reproduce reciprocal epithelial and epithelial interactions and epithelial and mesenchymal interactions that occur during embryogenesis. The book then discusses the generation of several 3D functional organs and organoids such as brain, inner ear, tooth, hair, salivary glands, lacrimal glands, gastrointestinal organs, kidney, liver, and lung. This work will appeal to a wide readership such as medical scientists, developmental biologists, clinicians, and patients. The volume provides valuable information and ideas to form a next-generation field of science.
Stem Cells Regenerative Medicine
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Author : Krishnarao Appasani
language : en
Publisher: Humana Press
Release Date : 2011-07-21
Stem Cells Regenerative Medicine written by Krishnarao Appasani and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-21 with Science categories.
Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.
Innovations In Molecular Mechanisms And Tissue Engineering
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Author : Jeanne Wilson-Rawls
language : en
Publisher: Springer
Release Date : 2016-12-10
Innovations In Molecular Mechanisms And Tissue Engineering written by Jeanne Wilson-Rawls and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-10 with Science categories.
This book marries stem cell biology, tissue engineering, and regenerative biology into a single, interdisciplinary volume. The chapters also explore embryonic stem cells, induced pluripotent stem cells, cardiovascular regeneration, skeletal development, inflammation, polymeric biomaterials, neural injury, cartilage regeneration, regeneration in ambystoma, models for regeneration using salamander and zebrafish, and more. The volume also discusses recent advances and their potential in developing future therapies. Innovations in Molecular Mechanisms and Tissue Engineering combines perspectives from the biomedical, bioengineering, and medical fields to present a cutting-edge, multifaceted picture of the tissue engineering and regenerative medicine fields. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is ideal for scientists, clinicians, and researchers in the fields of stem cell biology, regenerative medicine, biomedical engineering, and tissue engineering.
Principles Of Regenerative Medicine
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Author : Anthony Atala
language : en
Publisher: Academic Press
Release Date : 2018-08-09
Principles Of Regenerative Medicine written by Anthony Atala and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-09 with Medical categories.
Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies. Comprehensively covers the interdisciplinary field of regenerative medicine with contributions from leaders in tissue engineering, cell and developmental biology, biomaterials sciences, nanotechnology, physics, chemistry, bioengineering and surgery Includes new chapters devoted to iPS cells and other alternative sources for generating stem cells as written by the scientists who made the breakthroughs Edited by a world-renowned team to present a complete story of the development and promise of regenerative medicine