Regulation Of G Protein Coupled Receptor Function And Expression


Regulation Of G Protein Coupled Receptor Function And Expression
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Regulation Of G Protein Coupled Receptor Function And Expression


Regulation Of G Protein Coupled Receptor Function And Expression
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Author : Jeffrey L. Benovic
language : en
Publisher:
Release Date : 2000

Regulation Of G Protein Coupled Receptor Function And Expression written by Jeffrey L. Benovic and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.


This comprehensive text describes many techniques that are used to define the molecular mechanisms involved in receptor regulation. It covers a broad range of important concepts and methodologies in the study of G protein-coupled receptors.



Regulation Of G Protein Coupled Receptors


Regulation Of G Protein Coupled Receptors
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Author : Jeffrey L. Benovic
language : en
Publisher:
Release Date : 1997-07-01

Regulation Of G Protein Coupled Receptors written by Jeffrey L. Benovic and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-07-01 with Science categories.




The G Protein Coupled Receptors Handbook


The G Protein Coupled Receptors Handbook
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Author : Lakshmi A. Devi
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-01

The G Protein Coupled Receptors Handbook written by Lakshmi A. Devi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-01 with Medical categories.


A comprehensive survey of the many recent advances in the field of G protein-coupled receptors (GPCR). The authors describe the current knowledge of GPCR receptor structure and function, the different mechanisms involved in the regulation of GPCR function, and the role of pharmacological chaperones in GPCR folding and maturation. They also present new findings about how GPCR dimerization/oligomerization modifies the properties of individual receptors and show how recent developments are leading to significant advances in drug discovery, such as the detection of ligands for orphan GPCRs. Also discussed are the most recent developments that could lead to new drug discoveries: the role of GPCRs in mediating pain, the development of receptor-type selective drugs based on the structural plasticity of receptor activation, and the identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.



G Protein Coupled Receptors Part A


G Protein Coupled Receptors Part A
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Author :
language : en
Publisher: Elsevier
Release Date : 2022-11-08

G Protein Coupled Receptors Part A written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-08 with Science categories.


G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes. Covers a broad range of topics related to GPCR activation and signaling Covers several receptor systems with an emphasis on emerging paradigms Covers different processes and model systems with a focus on GPCRs



G Protein Coupled Receptors In Drug Discovery


G Protein Coupled Receptors In Drug Discovery
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Author : Kenneth H. Lundstrom
language : en
Publisher: CRC Press
Release Date : 2005-07-11

G Protein Coupled Receptors In Drug Discovery written by Kenneth H. Lundstrom and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-07-11 with Medical categories.


The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological roles of GPCRs



G Protein Coupled Receptors Emerging Paradigms In Activation Signaling And Regulation Part A


G Protein Coupled Receptors Emerging Paradigms In Activation Signaling And Regulation Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2018-04-23

G Protein Coupled Receptors Emerging Paradigms In Activation Signaling And Regulation Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-23 with Science categories.


G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation, Part A, Volume 337 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This new release includes comprehensive sections on the classical paradigms of GCPR signaling and regulation, the family of small GTPases: Beyond heterotrimeric G proteins, GPCR endocytosis: Arrestins, arrestin-like proteins, signaling from internalized G Protein-Coupled Receptors, GPCR kinases, and more. Publishes only invited review articles on selected topics Authored by established and active cell and molecular biologists whose work is drawn from international sources Offers a wide range of perspectives on specific subjects



G Protein Coupled Receptors In Immune Response And Regulation


G Protein Coupled Receptors In Immune Response And Regulation
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-09-23

G Protein Coupled Receptors In Immune Response And Regulation written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-23 with Medical categories.


G Protein-Coupled Receptors in Immune Response and Regulation, Volume 136 presents emerging concepts related to the role of GPCRs in immune response and regulation. Users will find updated chapters on a variety of topics, including Beta-adrenergic signaling in the onset and progression of asthma, the Emerging roles of Regulators of G protein signaling (RGS) proteins in the immune system, information on Kinin receptors in immune response and pathogenic infections, and sections on GPCR signaling in C. elegans and its implications in immune response, GPCR Kinases in Inflammatory response and signaling, and GRK2 in Inflammation: Regulation of T cell receptors and IgE signaling. Chapters in this book discuss not only the well-known aspects of GPCR signaling in immunology, but also presents many emerging paradigms that have not yet been reported in classical textbooks. Each chapter presents a forward-looking discussion, providing a glimpse of the tremendous potential associated with the specific receptor systems discussed. Brings together contributions from leading experts in the area of GPCR biology Discusses current paradigms and the future potential of understanding GPCR signaling in immune response and regulation Presents the first of its kind book to focus on specific GPCR systems in various aspects of immunology, all brought together in one volume



G Protein Coupled Receptors Part B


G Protein Coupled Receptors Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-01-25

G Protein Coupled Receptors Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-25 with Science categories.


G Protein-Coupled Receptors, Part B, Volume 195 represents the largest class of cell H103 surface proteins that have intricate involvement in nearly every physiological process in our body. Approximately one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. Sections in this volume include Adhesion G protein-coupled receptors: Structure and functions, Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle, Probing the orphan receptors: Tools and directions, Asymmetric activation of Class C GPCRs, Common and selective signal transduction mechanisms of GPCRs, and much more. Covers a broad range of topics related to GPCR activation and signaling Provides several receptor systems, with an emphasis on emerging paradigms Includes different processes and model systems, with a focus on GPCRs



G Protein Coupled Receptors


G Protein Coupled Receptors
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-02-26

G Protein Coupled Receptors written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-26 with Science categories.


G-Protein-Coupled Receptors: Signaling, Trafficking, and Regulation, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in G-Protein-Coupled Receptors, and includes sections on such topics signaling, trafficking and regulation. Covers the increasingly appreciated cell biology field of G-protein-coupled receptors Includes both established and new technologies Contributed by experts in the field Covers topics such as signaling, trafficking, and regulation



Principles Of Endocrinology And Hormone Action


Principles Of Endocrinology And Hormone Action
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Author : Antonino Belfiore
language : en
Publisher: Springer
Release Date : 2018-02-08

Principles Of Endocrinology And Hormone Action written by Antonino Belfiore and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-08 with Medical categories.


This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.