Regulation Of Gene Expression


Regulation Of Gene Expression
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Regulation Of Gene Expression


Regulation Of Gene Expression
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Author : Gary H. Perdew
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-17

Regulation Of Gene Expression written by Gary H. Perdew and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-17 with Science categories.


The use of molecular biology and biochemistry to study the regulation of gene expression has become a major feature of research in the biological sciences. Many excellent books and reviews exist that examine the experimental methodology employed in specific areas of molecular biology and regulation of gene expression. However, we have noticed a lack of books, especially textbooks, that provide an overview of the rationale and general experimental approaches used to examine chemically or disease-mediated alterations in gene expression in mammalian systems. For example, it has been difficult to find appropriate texts that examine specific experimental goals, such as proving that an increased level of mRNA for a given gene is attributable to an increase in transcription rates. Regulation of Gene Expression: Molecular Mechanisms is intended to serve as either a textbook for graduate students or as a basic reference for laboratory personnel. Indeed, we are using this book to teach a graduate-level class at The Pennsylvania State University. For more details about this class, please visit http://moltox. cas. psu. edu and select “Courses. ” The goal for our work is to provide an overview of the various methods and approaches to characterize possible mechanisms of gene regulation. Further, we have attempted to provide a framework for students to develop an understanding of how to determine the various mechanisms that lead to altered activity of a specific protein within a cell.



Regulation Of Gene Expression


Regulation Of Gene Expression
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Author : U Satyanarayana
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-11-07

Regulation Of Gene Expression written by U Satyanarayana and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-07 with Medical categories.


Regulation of gene expression Regulation of gene expression



Transcriptomics And Gene Regulation


Transcriptomics And Gene Regulation
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Author : Jiaqian Wu
language : en
Publisher: Springer
Release Date : 2015-11-17

Transcriptomics And Gene Regulation written by Jiaqian Wu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-17 with Science categories.


This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulation, including the tools for next generation sequencing analyses, alternative spicing, the modeling of signaling pathways, network analyses in predicting disease genes, as well as protein and gene expression data integration in complex human diseases etc. The book is particularly useful for researchers and students in the field of molecular biology, clinical biology and bioinformatics, as well as physicians etc. Dr. Jiaqian Wu is assistant professor in the Vivian L. Smith Department of Neurosurgery and Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Centre, Houston, TX, USA.​



Mechanisms Of Gene Regulation How Science Works


Mechanisms Of Gene Regulation How Science Works
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Author : Carsten Carlberg
language : en
Publisher: Springer Nature
Release Date : 2020-10-29

Mechanisms Of Gene Regulation How Science Works written by Carsten Carlberg and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-29 with Medical categories.


This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. Th is pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation.



Epigenetic Gene Expression And Regulation


Epigenetic Gene Expression And Regulation
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Author : Suming Huang
language : en
Publisher: Academic Press
Release Date : 2015-10-19

Epigenetic Gene Expression And Regulation written by Suming Huang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-19 with Science categories.


Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring Chapters are replete with clinical examples to empower the basic biology with translational significance Offers more than 100 illustrations to distill key concepts and decipher complex science



Gene Control Second Edition


Gene Control Second Edition
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Author : David Latchman
language : en
Publisher: Garland Science
Release Date : 2015-02-20

Gene Control Second Edition written by David Latchman and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-20 with Science categories.


The new edition of Gene Control has been updated to include significant advances in the roles of the epigenome and regulatory RNAs in gene regulation. The chapter structure remains the same: the first part consists of pairs of chapters that explain the mechanisms involved and how they regulate gene expression, and the second part deals with specific biological processes (including diseases) and how they are controlled by genes. Coverage of methodology has been strengthened by the inclusion more explanation and diagrams.The significant revision and updating will allow Gene Control to continue to be of value to students, scientists and clinicians interested in the topic of gene control.



Regulation Of Gene Expression By Small Rnas


Regulation Of Gene Expression By Small Rnas
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Author : Rajesh K. Gaur
language : en
Publisher: CRC Press
Release Date : 2009-04-27

Regulation Of Gene Expression By Small Rnas written by Rajesh K. Gaur and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-27 with Science categories.


New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p



Regulation Of Gene Expression In Escherichia Coli


Regulation Of Gene Expression In Escherichia Coli
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Author : E. C. C. Lin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Regulation Of Gene Expression In Escherichia Coli written by E. C. C. Lin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This up-to-date guide focuses on the understanding of key regulatory mechanisms governing gene expression in Escherichia coli. Studies of E. coli not only provide the first models of gene regulation, but research continues to yield different control mechanisms.



Gene Regulation In Eukaryotes


Gene Regulation In Eukaryotes
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Author : Edgar Wingender
language : en
Publisher: Vch Pub
Release Date : 1993

Gene Regulation In Eukaryotes written by Edgar Wingender and has been published by Vch Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Science categories.


A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 ( ) literature references.



The Regulatory Genome


The Regulatory Genome
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Author : Eric H. Davidson
language : en
Publisher: Elsevier
Release Date : 2010-07-19

The Regulatory Genome written by Eric H. Davidson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-19 with Science categories.


Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams