Renal Pharmacotherapy
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Renal Pharmacotherapy
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Author : Larry K. Golightly
language : en
Publisher: Springer Nature
Release Date : 2021-09-24
Renal Pharmacotherapy written by Larry K. Golightly and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-24 with Medical categories.
To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function. Failure to enjoin appropriate dosage adjustments in patients with abnormal or rapidly changing kidney function continues to lead to reports of drug toxicity involving a broad array of renally eliminated medications. This updated edition captures nearly 200 new drugs that have been approved by the FDA since the initial publication of Renal Pharmacotherapy. It also covers new evidence that has emerged regarding the need to adjust dosage of certain older medications that are eliminated by the kidneys. Additionally, it presents new data that are being continuously derived in the areas of patient-specific dose individualization for drugs of all types. Comprehensive, convenient, and evidence-based, this reference closes several identified knowledge gaps and will continue to be the leading collection of dosage recommendations for patients with compromised kidney function.
Renal Pharmacology
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Author : Manuel Martinez-Maldonado
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Renal Pharmacology written by Manuel Martinez-Maldonado and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Frequently attempts to design experiments utilizing the methodology de scribed in articles in trade journals can be frustrating. Description of procedures, because of space constraints, are not always complete. The present volume attempts to bring together in one reference source many of the techniques which are utilized in the study of the kidney. It provides a thorough compendium of research tools, framed by the critical analysis of the theoretical background of renal physiology, biochemistry, and pharmacology discussed in Volume 4A. Some areas previously dealt with are not covered from a methodological point of view since adequate information does exist elsewhere (e.g., methods of whole kidney ATPase isolation). Since drugs acting on the kidney may alter not only functional but anatomical integrity, a chapter on the preparation of tissue for morphological studies has been included. The important developments in analy sis of minute (ultramicro) quantities of tissue and biological fluids, as well as methodological advances in studies of the isolated kidney, are thoroughly covered. It is my hope that investigators, research fellows, and graduate students will benefit from the information contained in this volume and that, together with its companion tome, it will be a ready reference for the renal physiologist, the renal pharmacologist, and the nephrologist. The contributors have provided painstaking descriptions and, when re quired, mathematical analyses of the techniques described herein. I wish to thank all of them for their enthusiasm and the excellence of their contributions.
Pharmacotherapy Of Renal Disease And Hypertension
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Author : William M. Bennett
language : en
Publisher:
Release Date : 1987
Pharmacotherapy Of Renal Disease And Hypertension written by William M. Bennett and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Hypertension categories.
Renal Medicine And Clinical Pharmacy
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Author : Rhiannon Braund
language : en
Publisher: Springer Nature
Release Date : 2020-07-08
Renal Medicine And Clinical Pharmacy written by Rhiannon Braund and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-08 with Medical categories.
This first volume of an exciting new book series offers a comprehensive and logically organized introduction to clinical pharmacy as applied to renal medicine. The volume opens with a review of renal pharmacokinetics: absorption; distribution; metabolism; and elimination, as well as drug dosing in renal impairment, and important knowledge specific to aging and renal impairment. Acute kidney injury receives extensive attention, including pre-renal, intra-renal, and post-renal injuries. The book also outlines the role of clinical pharmacy in chronic kidney disease and end stage renal failure. Additional chapters provide detailed information on the methods and pharmacokinetics of renal dialysis, and the epidemiology and management of drug-induced nephrotoxicity. The Advanced Clinical Pharmacy series provides a review of core pharmaceutical concepts, a foundation for optimizing pharmacotherapy, and an introduction to advanced clinical practice. The editors and contributors are international experts who distill the core knowledge of each specialty. The books offer real-world insights to benefit both new practitioners, and experienced pharmacists exploring new areas of clinical pharmacy
Renal Pharmacology
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Author : James William Fisher
language : en
Publisher:
Release Date : 1971
Renal Pharmacology written by James William Fisher and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Kidneys categories.
Papers presented at a renal pharmacology conference in the Dept. of Pharmacology, Tulane University School of Medicine in New Orleans, La., Jan. 13, 1970, held in connection with the joint meetings of the U. S. Public Health Service Pharmacology A and Medicine B Study Sections.
Methods In Pharmacology
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Author : Manuel Martinez-Maldonado
language : en
Publisher: Springer
Release Date : 2012-02-05
Methods In Pharmacology written by Manuel Martinez-Maldonado and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-05 with Medical categories.
In the years since Homer Smith did his pioneering work in renal physiology, interest in the kidney has grown steadily and robustly. That this wondrously designed machine-in addition to its filtering, secreting, and reabsorptive functions-can serve as an important endocrine organ has made it the investiga tive concern of researchers from a variety of disciplines. Not surprisingly in this era of molecular biology, attempts have been made to understand the orderly functions of the kidney in biochemical and molecular terms, and this has led to the steady entry of renal physiologists and pharmacologists into these areas. Because renal physiology is the foundation on which renal pharmacology is based, this volume has been directed toward describing and interpreting the interrelationships of these two disciplines and their relation to the biochemistry and biophysics of the kidney. Accordingly, extensive critical discussions of the current knowledge of mechanisms affected by pharmacological agents, in addition to descriptions of methods, have been included herein. Not acciden tally, stress is placed on the physiological, pharmacological, and biochemical effect of diuretics. In a specific sense the drugs in this group are true "renal drugs." The scope of the material included on diuretics is wide enough that this book should be of value to almost anyone involved in their use, from the clinician to the cell biologist.
Methods In Pharmacology
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Author : Manuel Martínez-Maldonado
language : en
Publisher:
Release Date : 1978
Methods In Pharmacology written by Manuel Martínez-Maldonado and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with categories.
Hydrogen Sulfide In Kidney Diseases
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Author : George J. Dugbartey
language : en
Publisher: Springer Nature
Release Date : 2023-12-23
Hydrogen Sulfide In Kidney Diseases written by George J. Dugbartey and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-23 with Medical categories.
This book will be the first book that presents the beneficial effects of hydrogen sulfide in the treatment of various kidney pathologies. Hydrogen sulfide (H2S), a gas with a distinctive smell of rotten eggs, was known for over three centuries for its toxicity and death at high concentrations especially among agricultural and industrial workers. This is due to its ability to reversibly antagonize complex IV of the mitochondrial electron transport chain. However, studies over the past two decades have shown that H2S has risen above its historic notorious label and has received significant experimental attention as an endogenously produced gaseous signaling molecule that plays an important role in cellular homeostasis and influences a myriad of physiological and pathological processes at low concentrations. Its production is enzymatically regulated and has specific molecular targets. Several recent in vitro and in vivo studies have demonstrated that at low micromolar concentrations, H2S exhibits important therapeutic characteristics that target multiple molecular pathways and thereby preventing the development and progression of several pathologies. This beneficial effect of H2S suggests that it may meet the demand for alternative and/or additional therapeutic agents against various renal pathologies in which reduced levels of renal and plasma H2S were observed. Interestingly, while the distribution of H2S-producing enzymes is tissue-specific, they are abundantly expressed in the glomeruli and in the brush border and cytoplasm of epithelial cells of the renal tubules and in the peritubular capillaries. This makes the kidney a rich source of endogenous H2S production. From pre-clinical and clinical perspectives, this book is topical and timely, and seeks to lay the foundation for future clinical applications of H2S in nephrology.
Renal Pharmacology
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Author : Manuel Martinez-Maldonado
language : en
Publisher:
Release Date : 2014-01-15
Renal Pharmacology written by Manuel Martinez-Maldonado and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.
Clinical Nephrotoxins
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Author : Marc E. de Broe
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Clinical Nephrotoxins written by Marc E. de Broe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
GEORGE A. PORTER information is an international commodity whose The field of clinical nephrotoxicity involves toxins of interpretation and application are strongly influenced diverse origin and exposure. A significant contribution by both the cultural and ethnic background of the to this problem arises from registered and non-regis observer. The opportunity to share in the rich diversity tered drugs either prescribed or purchased over the of the international scientific community was a fun counter. Another major contributor comes from occu pational or industrial exposures. Each situation pre damental goal of this endeavor. To participate as sents the nephrologist with unique challenges con equals leads to mutual respect and peer appreciation. cerning diagnosis, confirrnation, and treatment includ The sharing of intellectual resources which such an ing limitation from future exposure. In selecting drugs effort fosters, should facilitate the advancement of for inclusions in this book the editors were guided by sound science. both frequency and current knowledge. For occupa Our approach to the field of nephrotoxicity is from tionall environmental exposures similar guidelines the perspective of a book which will be of value to the were applied. As one reviews the world's literature clinician. In this respect we have chosen compounds concerning nephrotoxicity two types of investigation wh ich are of current importance to the nephrologist and his/her patient rather than of historical interest.