Retinal Development

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Retinal Development

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Author : Evelyne Sernagor
language : en
Publisher: Cambridge University Press
Release Date : 2012-11-29

Retinal Development written by Evelyne Sernagor and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-29 with Medical categories.

This advanced text, first published in 2006, takes a developmental approach to the presentation of our understanding of how vertebrates construct a retina. Written by experts in the field, each of the seventeen chapters covers a specific step in the process, focusing on the underlying molecular, cellular, and physiological mechanisms. There is also a special section on emerging technologies, including genomics, zebrafish genetics, and stem cell biology that are starting to yield important insights into retinal development. Primarily aimed at professionals, both biologists and clinicians working with the retina, this book provides a concise view of vertebrate retinal development. Since the retina is 'an approachable part of the brain', this book will also be attractive to all neuroscientists interested in development, as processes required to build this exquisitely organized system are ultimately relevant to all other parts of the central nervous system.

Vertebrate Eye Development

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Author : M. Elizabeth Fini
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-07

Vertebrate Eye Development written by M. Elizabeth Fini and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-07 with Science categories.

"Who would believe that so small a space could contain the images of all the universe?" Leonardo da Vinci The last years of the 20th century have found the discipline of Developmental Biology returning to its original position at the forefront of biological re search. This progress can be attributed to the burgeoning knowledge base on molecules and gene families, and to the power of the molecular genetic ap proach. Topping the list of organ systems which have provided the most significant advances would have to be the eye. The vertebrate eye was one of the classic embryologic models, used to demonstrate many important prin ciples, including the concepts of inductive tissue interactions first put forth in the early 1900s. Within the last decade of this century, a return to some of the old questions with the new approaches has put eye development back into the limelight. I find this a highly appropriate topic for a book which aims to spark research for the new millennium. We begin with a chapter that discusses the anatomy of eye development, providing the basic reference information for the chapters that follow. A novel aspect of this introduction is the connection made between develop mental strategies and the eye's optical function. What also emerges from this chapter is the number of important eye structures that have barely been touched by the modern developmental biologist. Work on cornea and ante rior chamber development has lagged behind lens and retina.

Development Of The Visual System

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Author : S.P. Bhat
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2004-01-01

Development Of The Visual System written by S.P. Bhat and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-01 with Medical categories.

All the tissues of the eye, including the lens, the cornea, the ciliary body, the neuroretina and the retinal pigment epithelium must work in harmony for the realization of clear vision.The phenotypic emergence of each of these tissues requires intercellular communication, which is achieved through direct physical contact as well as through diffusion and reception of the molecular beacons.This volume provides an overview of the molecular and cellular biology of eye development and encompasses themes like early gene expression in the surface ectoderm and the optic cup, retinal neurogenesis, signaling molecules and axonal guidance. It presents new findings on the influence of the lens on the development of the visual system and how gene expression in the optic cup controls differentiation of the lens fiber cell while established ideas about the morphogenesis of the ciliary body are challenged. A valuable source of information for developmental biologists and neurobiologists as well as ophthalmologists interested in understanding the relationship between temporally and spatially regulated gene activity and function and cellular interactions in early development and neuronal functions.

Invertebrate And Vertebrate Eye Development

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Author :
language : en
Publisher: Academic Press
Release Date : 2010-11-24

Invertebrate And Vertebrate Eye Development written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-24 with Science categories.

Vision is our primary sensory modality, and we are naturally curious as to how the visual system assembles. The visual system is in many ways remarkably simple, a repeating assemblage of neurons and support cells that parse the visual field through precision and redundancy. Through this simplicity the eye has often led the way in our exploration of how an organ is assembled. Eye development has therefore long been a favorite for exploring mechanisms of cell fate choice, patterning and cell signaling.This volume, which is part of the Current Topics in Developmental Biology series, highlights the exceptional advances over the past 20 years. Chapters emphasize our knowledge of transcription factors and how these generate networks to direct the eye field and associated structures. Topics such as cell fate specification are also explored, along with the potential of Drosophila as a model for lens formation and the progress made in using the Drosophila eye to examine planar cell polarity. - Contributions from researchers who are active in identifying new paradigms to explore - Review of our current state of knowledge - Chapters written by authors with a new generation approach that takes a more systems approach to identifying factors and better defines cell subtypes

Drosophila Eye Development

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Author : Kevin Moses
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-03-12

Drosophila Eye Development written by Kevin Moses and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-12 with Medical categories.

1 Kevin Moses It is now 25 years since the study of the development of the compound eye in Drosophila really began with a classic paper (Ready et al. 1976). In 1864, August Weismann published a monograph on the development of Diptera and included some beautiful drawings of the developing imaginal discs (Weismann 1864). One of these is the first description of the third instar eye disc in which Weismann drew a vertical line separating a posterior domain that included a regular pattern of clustered cells from an anterior domain without such a pattern. Weismann suggested that these clusters were the precursors of the adult ommatidia and that the line marks the anterior edge of the eye. In his first suggestion he was absolutely correct - in his second he was wrong. The vertical line shown was not the anterior edge of the eye, but the anterior edge of a moving wave of patterning and cell type specification that 112 years later (1976) Ready, Hansen and Benzer would name the "morphogenetic furrow". While it is too late to hear from August Weismann, it is a particular pleasure to be able to include a chapter in this Volume from the first author of that 1976 paper: Don Ready! These past 25 years have seen an astonishing explosion in the study of the fly eye (see Fig.

Genetic Features Contributing To Eye Development And Disease

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Author : Ling Zhao
language : en
Publisher: Frontiers Media SA
Release Date : 2022-10-19

Genetic Features Contributing To Eye Development And Disease written by Ling Zhao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-19 with Science categories.

Retina

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Author : David R. Hinton
language : en
Publisher: Elsevier Health Sciences
Release Date : 2005-09-21

Retina written by David R. Hinton and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-21 with Medical categories.

Praised by JAMA as "The most complete description of the development, structure, function, pathophysiology, and treatment of the retina and its diseases to be found anywhere," this monumental three-volume work puts all of today's scientific and clinical knowledge of the retina at readers' fingertips. The New Edition has been comprehensively updated and reorganized to reflect all of the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques. The result is an indispensable reference and diagnostic tool for generalists and specialists alike. Delivers the editorial expertise of four highly respected authorities, as well as contributions from internationally recognized leaders in visual science, ophthalmology, and vitreoretinal studies. Presents more than 3,400 superb illustrations (2,200 in full color) that capture all forms of retinal disease from every perspective. Offers the very latest information on the genetic basis of retinal disease, diagnostic retinal imaging, photodynamic therapy, and age-related macular degeneration. Examines the most recent advances in diagnostic indocyanine green angiography � optical coherence tomography (OCT) and quantitative fluoroscein angiography � macular translocation with 360� peripheral retinectomy � surgery for diffuse macular edema due to multiple causes, including proliferative vitreoretinopathy � artificial vision � and much more. Features a completely restructured section on age-related macular degeneration that includes epidemiology and risk factors � prophylaxis and prevention knowledge gained from large clinical trials like AREDS � proven and experimental treatments for AMD � and pharmacotherapy. Incorporates a multitude of new full-color images, 2200 in all.

Retina E Book

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Author : Charles P. Wilkinson
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-11-01

Retina E Book written by Charles P. Wilkinson and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-01 with Medical categories.

Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.

Retinal Degenerative Diseases

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Author : Catherine Bowes Rickman
language : en
Publisher: Springer
Release Date : 2015-10-01

Retinal Degenerative Diseases written by Catherine Bowes Rickman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-01 with Medical categories.

Contains the proceedings of the XVI International Symposium on Retinal Degeneration (RD2014), to be held July 13-18, 2014 at the Asilomar Conference Center in Pacific Grove, California. A majority of those who will speak and present posters at the meeting will contribute to this volume. The Symposium addresses the blinding diseases of inherited retinal degenerations, which have no effective treatments and age-related macular degeneration, which has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 75. The RD2014 Symposium will focus on the exciting new developments aimed at understanding these diseases and providing therapies for them. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy; and several sight restoration approaches, including optogenetics. While advances in these areas of retinal degenerations will be included, several new topics either were in their infancy or did not exist at the time of the last RD Symposium, RD2012. These include many new developments in sight restoration using optogenetics, retinal or RPE cell transplantation, stem cell approaches and visual prosthetic devices. In addition, major advances will be presented in other basic mechanisms in age-related macular degeneration, several new aspects of gene and antioxidant therapy and revolutionary new imaging and functional testing that will have a huge impact on the diagnosis and following the course of retinal degenerations, as well as to provide new quantitative endpoints for clinical trials. The retina is an approachable part of the central nervous system (CNS), and there is a major interest in neuroprotective and gene therapy for CNS diseases and neurodegenerations, in general. It should be noted that with successful and exciting initial clinical trials in neuroprotective and gene therapy, including the restoration of sight in blind children, the retinal degeneration therapies are leading the way towards new therapeutic measures for neurodegenerations of the CNS. Many of the successes recently reported in these areas of retinal degeneration sprang from collaborations established at previous RD Symposia, and many of those will be reported at the RD2014 meeting and included.

The Retina And Its Disorders

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Author : Joseph Besharse
language : en
Publisher: Academic Press
Release Date : 2011-04-25

The Retina And Its Disorders written by Joseph Besharse and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-25 with Medical categories.

This selection of articles from the Encyclopedia of the Eye covering retina, optics/optic nerve and comparative topics constitutes the first reference for scientists, post docs, and graduate students with an interest beyond standard textbook materials. It covers the full spectrum of research on the retina - from the basic biochemistry of how nerve cells are created to information on neurotransmitters, comparisons of the structure and neuroscience of peripheral vision systems in different species, and all the way through to injury repair and other clinical applications. The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of the retina Chapters are carefully selected from the Encyclopedia of the Eye by one of the world's leading vision researchers The best researchers in the field provide their conclusions in the context of the latest experimental results