Retrometabolic Drug Design And Targeting


Retrometabolic Drug Design And Targeting
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Retrometabolic Drug Design And Targeting


Retrometabolic Drug Design And Targeting
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Author : Nicholas Bodor
language : en
Publisher: John Wiley & Sons
Release Date : 2012-08-29

Retrometabolic Drug Design And Targeting written by Nicholas Bodor and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-29 with Science categories.


Innovative approach to drug design that's more likely to result in an approvable drug product Retrometabolic drug design incorporates two distinct drug design approaches to obtain soft drugs and chemical delivery systems, respectively. Combining fundamentals with practical step-by-step examples, Retrometabolic Drug Design and Targeting gives readers the tools they need to take full advantage of retrometabolic approaches in order to develop safe and effective targeted drug therapies. The authors, both pioneers in the fields of soft drugs and retrometabolic drug design, offer valuable ideas, approaches, and solutions to a broad range of challenges in drug design, optimization, stability, side effects, and toxicity. Retrometabolic Drug Design and Targeting begins with an introductory chapter that explores new drugs and medical progress as well as the challenges of today's drug discovery. Next, it discusses: Basic concepts of the mechanisms of drug action Drug discovery and development processes Retrometabolic drug design Soft drugs Chemical delivery systems Inside the book, readers will find examples from different pharmacological areas detailing the rationale for each drug design. These examples set forth the relevant pharmacokinetic and pharmacodynamic properties of the new therapeutic agents, comparing these properties to those of other compounds used for the same therapeutic purpose. In addition, the authors review dedicated computer programs that are available to support and streamline retrometabolic drug design efforts. Retrometabolic Drug Design and Targeting is recommended for all drug researchers interested in employing this newly tested and proven approach to developing safe and effective drugs.



Exam 77 881 Microsoft Word 2010 High School Version With Wp V5 Card Set


Exam 77 881 Microsoft Word 2010 High School Version With Wp V5 Card Set
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Author : Microsoft Official Academic Course
language : en
Publisher: Wiley
Release Date : 2012-07-21

Exam 77 881 Microsoft Word 2010 High School Version With Wp V5 Card Set written by Microsoft Official Academic Course and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-21 with Computers categories.




Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software Set


Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software Set
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Author : Microsoft Official Academic Course
language : en
Publisher: Wiley
Release Date : 2012-07-19

Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software Set written by Microsoft Official Academic Course and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-19 with Computers categories.




Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With Wileyplus Blackboard Card


Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With Wileyplus Blackboard Card
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Author : MOAC
language : en
Publisher:
Release Date : 2012-05-04

Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With Wileyplus Blackboard Card written by MOAC and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-04 with categories.




Transformative Concepts For Drug Design Target Wrapping


Transformative Concepts For Drug Design Target Wrapping
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Author : Ariel Fernandez
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-28

Transformative Concepts For Drug Design Target Wrapping written by Ariel Fernandez and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-28 with Technology & Engineering categories.


In spite of the enticing promises of the post-genomic era, the pharmaceutical world is in a state of disarray. Drug discovery seems now riskier and more uncertain than ever. Thus, projects get routinely terminated in mid-stage clinical trials, new targets are getting harder to find, and successful therapeutic agents are often recalled as unanticipated side effects are discovered. Exploiting the huge output of genomic studies to make safer drugs has proven to be much more difficult than anticipated. More than ever, the lead in the pharmaceutical industry depends on the ability to harness innovative research, and this type of innovation can only come from one source: fundamental knowledge. This book squarely addresses this crucial problem since it introduces fundamental discoveries in basic biomolecular research that hold potential to broaden the technological base of the pharmaceutical industry. The book takes a fresh and fundamental look at the problem of how to design an effective drug with controlled specificity. Since the novel transformative concepts are unfamiliar to most practitioners, the first part of this book explains matters very carefully starting from a fairly elementary physico-chemical level. The second part of the book is devoted to practical applications, aiming at nothing less than a paradigm shift in drug design. This book is addressed to scientists working at the cutting edge of research in the pharmaceutical industry, but the material is at the same time accessible to senior undergraduates or graduate students interested in drug discovery and molecular design.



Exam 77 881 Microsoft Word 2010 W Microsoft Office 2010 Evaluation Software With 2010 77 882 885 App Ms Offc10 Eval Sftw Set


Exam 77 881 Microsoft Word 2010 W Microsoft Office 2010 Evaluation Software With 2010 77 882 885 App Ms Offc10 Eval Sftw Set
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FREE 30 Days

Author : Microsoft Official Academic Course
language : en
Publisher: Wiley
Release Date : 2013-01-31

Exam 77 881 Microsoft Word 2010 W Microsoft Office 2010 Evaluation Software With 2010 77 882 885 App Ms Offc10 Eval Sftw Set written by Microsoft Official Academic Course and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-31 with Computers categories.


This book provides researchers in drug discovery and design with complete guidance on how to use retrometabolic approaches to develop safe, effective, and targeted drug therapies. Written by pioneers in soft drugs and retrometabolics, the book brings together for the first time a wealth of information from across the literature, offering a single source of valuable ideas, methods, and references to the problems of drug design, optimization, stability, side effects, and toxicity. Authoritative coverage includes both important fundamentals and practical examples illustrating applications in drug design.



Biopharmaceutical Drug Design And Development


Biopharmaceutical Drug Design And Development
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Author : Susanna Wu-Pong
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-11

Biopharmaceutical Drug Design And Development written by Susanna Wu-Pong and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-11 with Medical categories.


This book provides a comprehensive examination of the newest biopharmaceutical drugs. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, and contains a review of the Human Genome Project.



Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With 77 881 Mos Rc 77 601 Cprep And Wp V5 Set


Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With 77 881 Mos Rc 77 601 Cprep And Wp V5 Set
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FREE 30 Days

Author : Microsoft Official Academic Course
language : en
Publisher: Wiley
Release Date : 2012-09-04

Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With 77 881 Mos Rc 77 601 Cprep And Wp V5 Set written by Microsoft Official Academic Course and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-04 with Computers categories.




Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With 77 882 Exc10 W Ms Offc10 Esw And 77 883 Ppt10 W Ms Offc Esw Set


Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With 77 882 Exc10 W Ms Offc10 Esw And 77 883 Ppt10 W Ms Offc Esw Set
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FREE 30 Days

Author : Microsoft Official Academic Course
language : en
Publisher: Wiley
Release Date : 2013-01-30

Exam 77 881 Microsoft Word 2010 With Microsoft Office 2010 Evaluation Software With 77 882 Exc10 W Ms Offc10 Esw And 77 883 Ppt10 W Ms Offc Esw Set written by Microsoft Official Academic Course and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-30 with Computers categories.




Successful Drug Discovery Volume 1


Successful Drug Discovery Volume 1
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Author : J¿nos Fischer
language : en
Publisher: John Wiley & Sons
Release Date : 2015-05-04

Successful Drug Discovery Volume 1 written by J¿nos Fischer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-04 with Medical categories.


The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds: small-molecule-, peptide-, and protein-based drugs. The role of serendipity is analyzed in some very successful drugs where the research targets of the lead molecule and the drug are different. Phenotypic and target-based drug discovery approaches are discussed from the viewpoint of pioneer drugs and analogues. This volume gives an excellent overview of insulin analogues including a discussion of the properties of rapid-acting and long-acting formulations of this important hormone. The major part of the book is devoted to case histories of new drug discoveries described by their key inventors. Eight case histories range across many therapeutic fields. The goal of this book series is to help the participants of the drug research community with a reference book series and to support teaching in medicinal chemistry with case histories and review articles of new drugs.