Retroviruses And Primate Genome Evolution
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Retroviruses And Primate Genome Evolution
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Author : Eugene D. Sverdlov
language : en
Publisher: CRC Press
Release Date : 2005-01-10
Retroviruses And Primate Genome Evolution written by Eugene D. Sverdlov and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-10 with Science categories.
Human Evolution
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Author : Graeme Finlay
language : en
Publisher: Cambridge University Press
Release Date : 2013-09-12
Human Evolution written by Graeme Finlay and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-12 with Medical categories.
Brings together new research demonstrating how evidence based on genetic phenomena should end any lingering controversy over human evolution.
Human Evolution
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Author : Graeme Finlay
language : en
Publisher: Cambridge University Press
Release Date : 2013-09-12
Human Evolution written by Graeme Finlay and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-12 with Science categories.
Controversy over human evolution remains widespread. However, the human genome project and genetic sequencing of many other species have provided myriad precise and unambiguous genetic markers that establish our evolutionary relationships with other mammals. Human Evolution: Genes, Genealogies and Phylogenies identifies and explains these identifiable, rare and complex markers including endogenous retroviruses, genome-modifying transposable elements, gene-disabling mutations, segmental duplications and gene-enabling mutations. The new genetic tools also provide fascinating insights into when and how many features of human biology arose: from aspects of placental structure, vitamin C dependence and trichromatic vision, to tendencies to gout, cardiovascular disease and cancer. Bringing together a decade's worth of research and tying it together to provide an overwhelming argument for the mammalian ancestry of the human species, the book will be of interest to professional scientists and students in both the biological and biomedical sciences.
Ancestors In Our Genome
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Author : Eugene E. Harris (Professor)
language : en
Publisher: Oxford University Press, USA
Release Date : 2015
Ancestors In Our Genome written by Eugene E. Harris (Professor) and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Science categories.
Geneticist Eugene Harris presents us with the complete and up-to-date account of the evolution of the human genome.
Discovering Retroviruses
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Author : Anna Marie Skalka
language : en
Publisher:
Release Date : 2018
Discovering Retroviruses written by Anna Marie Skalka and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
Eight percent of our DNA contains retroviruses that are millions of years old. Anna Marie Skalka explains how our evolving knowledge of these particles has advanced genetic engineering, gene delivery systems, and precision medicine. Retroviruses cause disease but also hold clues to prevention and treatment possibilities that are anything but retro.
Retroviruses Retroelements And Their Restrictions
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Author : Atsushi Koito
language : en
Publisher: Frontiers Media SA
Release Date : 2015-05-01
Retroviruses Retroelements And Their Restrictions written by Atsushi Koito and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-01 with HIV (Viruses) categories.
Human retroviruses, HIV and HTLV have been recognized as important pathogens because of their association with lethal diseases such as AIDS and ATL. Considerable resources and efforts have been directed at understanding the interaction between these retroviruses and their host which may provide clues as to how the infection can be controlled or prevented. Among the key scientific successes is the identification of intracellular “restriction factors” that have evolved as obstacles to the replication of pathogens including infectious retroviruses. The discovery of APOBEC, which are strong mutagens of retroviral genomes and intracellular retroelements, began a new era of intense research activities into the spectrum of intrinsic anti-HIV activity, leading to the identification of TRIM5a, BST2/Tetherin, and SAMHD1. In response, HIV has evolved several accessory genes as weaponries to evade these intracellular restriction activities. The intracellular antiretroviral defenses evolved in response to endogenous retroelements that make up more than 40% of the entire mammalian genome, and which are regarded as ancestors of infectious retroviruses. LTR-type retroelements are present in all higher eukaryotes, representing about 8% of the human genome. Non-LTR retroelements can be found at extremely high copy numbers also, with a significant portion of mammalin genomes consisting of LINEs. Mammalian genomes are modified by LINEs through insertions, but also by the indirect replication of non-autonomous retrotransposons such as SINEs. LINEs insertion was shown to have played, and continue to play important roles in genomic evolution and somatic genome mosaicism-mediated physiology. And, because retrotransposition can confer genetic diversity that is beneficial to the host, the vertebrate intrinsic immunity has evolved to support a balance between retroelement insertions that confer beneficial and those that cause deleterious gene disruptions. The articles published in this Research Topic should serve not only as valuable references for the field, but provide future topics of research for investigators that should further our understanding of the retrovirus, retroelements and their restrictions.
Vertebrate Genomes
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Author : Jean-Nicolas Volff
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2006-01-01
Vertebrate Genomes written by Jean-Nicolas Volff and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-01 with Science categories.
The publication of the first draft of the human genome five years ago marked the start of a new era of vertebrate comparative genomics. Genome draft sequences for chimpanzee, mouse, rat, dog, chicken as well as for several fish species are now available for the reconstruction of the evolutionary history of vertebrate genomes over the last 450 million years. This volume of Genome Dynamics presents a timely update on the past, present and future of major vertebrate genome projects. In 16 chapters, renowned specialists provide informative reviews on the current status of mammalian, bird, amphibian and fish genomics. In addition, a chapter on urochordate genomes is included. The reader will also find a useful overview of resources available for each genome as well as a description of the medical and economical perspectives opened by the different projects. This book is recommended reading for biologists interested in genetics, genomics, evolution and zoology.
Retroviruses
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Author : Reinhard Kurth
language : en
Publisher:
Release Date : 2010
Retroviruses written by Reinhard Kurth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
International Symposium Retroviruses And Human Pathology
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Author : Robert C. Gallo
language : en
Publisher: Springer Science & Business Media
Release Date : 1985
International Symposium Retroviruses And Human Pathology written by Robert C. Gallo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Medical categories.
For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.
Foamy Viruses
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Author : Axel Rethwilm
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-05-12
Foamy Viruses written by Axel Rethwilm and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-12 with Medical categories.
The aberrant replication pathway of foamy viruses distinguishes them from all other retroviruses. Many details have been accumulated over the past ten or so years. Most of the findings on foamy viruses were obtained by research on a single virus isolate previously called "human foamy virus", which appeared to be the first to be investigated on a molecular level. However, to the editor's knowledge, genuine human foamy viruses do not exist, but several trans-species transmissions of different simian foamy viruses from monkeys and apes to human hosts.