Revisiting Seed And Soil A New Approach To Target Hibernating Dormant Tumor Cells 2nd Edition
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Revisiting Seed And Soil A New Approach To Target Hibernating Dormant Tumor Cells 2nd Edition
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Author : Dalit Barkan
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-07
Revisiting Seed And Soil A New Approach To Target Hibernating Dormant Tumor Cells 2nd Edition written by Dalit Barkan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-07 with Medical categories.
Metastasis is the major cause of mortality in cancer patients. Metastases can be present at the time of diagnosis or can occur years or decades after the removal of the primary tumor and treatment. This long latency in the manifestation of recurrent metastatic disease is explained clinically by the persistence of quiescent tumor cells that disseminated early in the course of the disease from the primary tumor to select distant organs. These residing disseminated tumor cells (DTCs) at distant organs lay dormant and asymptomatic until reawakened to form overt metastases. Importantly, the quiescent nature of these “hibernating” DTCs facilitates their resistance to conventional therapies that target actively dividing tumor cells. Therefore, unraveling the biology of dormancy and reactivation of the residing DTCs to life-threatening lesions is of utmost importance in order to develop new therapeutic strategies to prevent the recurrent metastatic disease from ever emerging or to better treat these recurrent cancers. The mechanisms underlying the biology of tumor dormancy and their reactivation to overt metastases are just beginning to emerge thanks to a growing appreciation of the potentially chronic nature of some cancers and the development of experimental model systems for their study. In this Research Topic, we will follow the journey of circulating tumor cells (CTCs) dispatching from the primary site until their successful lodging into a new and foreign site to become DTCs. We will explore the intrinsic mechanisms along with microenvironmental cues and niches that they encounter during their journey that may dictate their fate.
Insect Diapause
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Author : David L. Denlinger
language : en
Publisher:
Release Date : 2022
Insect Diapause written by David L. Denlinger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Diapause categories.
"Our highly seasonal world imposes environmental challenges for insects. To survive these inimical periods they rely on a diapause (dormancy) mechanism to bridge unfavorable seasons. The origin of the term "diapause" is discussed, as well as its relationship to related forms of dormancy in other animals. Diapause is distinct from quiescence in that it is not an immediate response to an adverse environment but is programmed at an earlier developmental stage, an attribute that enables the insect to take steps in preparation for entering the arrested state. Diapause can occur at any point in the life cycle (embryo, larva, pupa, adult), but when it occurs is species-specific. The chapter summarizes who does it and in what stage, as well as addressing the occurrence of diapause in social insects. The pervasive impact of diapause on the insect life cycle begins prior to diapause and continues well beyond its termination"--
Insect Pests In Tropical Forestry
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Author : F. Ross Wylie
language : en
Publisher: CABI
Release Date : 2012
Insect Pests In Tropical Forestry written by F. Ross Wylie and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Technology & Engineering categories.
"The management of tropical forest ecosystems is essential to the health of the planet. This book addresses forest insect pest problems across the world's tropics, addressing the pests' ecology, impact and possible approaches for their control. Fully updated, this second edition also includes discussions of new areas of interest including climate change, invasive species, forest health and plant clinics. This work is an indispensible resource for students, researchers and practitioners of forestry, ecology, pest management and entomology in tropical and subtropical countries."--pub. desc.
Introduction To Plant Diseases
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Author : George B. Lucas
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Introduction To Plant Diseases written by George B. Lucas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.
Every year we see a remarkable increase in scientific knowledge. We are learning more each day about the world around us, about the numerous biological organisms of the biosphere, about the physical and chemical processes that shaped and continue to change our planet. The cataloging, retrieval, dissemination, and use of this new information along with the continued development of new computer technology provide some of the most challenging problems in science as we enter the Information Age. With the explosion of knowledge in science, it is especially important that students in introductory courses learn not only the basic material of a subject, but also about the newest developments in that subject. With this goal in mind, we have prepared a second edition of Introduction to Plant Diseases: Identification and Management. We prepared this edition with the same general purpose that we had for the first edition - to provide practical, up-to-date information that helps in the successful management of diseases on food, fiber, and landscape plants for students who do not have a strong background in the biological sciences. We included new information on (1) the precise identification of diseases and the pathogens that cause them, (2) the development of epidemics of plant diseases, (3) the application of biotechnology in plant pathology, (4) the use of alternative methods of crop production and disease management that help protect the environment, and (5) diseases that have become more important since the first edition was published.
Weed Ecology
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Author : Steven R. Radosevich
language : en
Publisher: John Wiley & Sons
Release Date : 1997-02-05
Weed Ecology written by Steven R. Radosevich and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-02-05 with Gardening categories.
Weeds are successful plants, but on their own terms. Looking at weeds from an ecological viewpoint, emphasising the way in which one species interacts with others, the authors show that weeds are questionable mainly in that they are out-of-place.
Probabilistic Structures In Evolution
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Author : Ellen Baake
language : en
Publisher:
Release Date : 2021
Probabilistic Structures In Evolution written by Ellen Baake and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Edible Insects
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Author : Arnold van Huis
language : en
Publisher: Bright Sparks
Release Date : 2013
Edible Insects written by Arnold van Huis and has been published by Bright Sparks this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Conservation of natural resources categories.
Edible insects have always been a part of human diets, but in some societies there remains a degree of disdain and disgust for their consumption. Although the majority of consumed insects are gathered in forest habitats, mass-rearing systems are being developed in many countries. Insects offer a significant opportunity to merge traditional knowledge and modern science to improve human food security worldwide. This publication describes the contribution of insects to food security and examines future prospects for raising insects at a commercial scale to improve food and feed production, diversify diets, and support livelihoods in both developing and developed countries. It shows the many traditional and potential new uses of insects for direct human consumption and the opportunities for and constraints to farming them for food and feed. It examines the body of research on issues such as insect nutrition and food safety, the use of insects as animal feed, and the processing and preservation of insects and their products. It highlights the need to develop a regulatory framework to govern the use of insects for food security. And it presents case studies and examples from around the world. Edible insects are a promising alternative to the conventional production of meat, either for direct human consumption or for indirect use as feedstock. To fully realise this potential, much work needs to be done by a wide range of stakeholders. This publication will boost awareness of the many valuable roles that insects play in sustaining nature and human life, and it will stimulate debate on the expansion of the use of insects as food and feed.
Global Re Introduction Perspectives 2013 Further Case Studies From Around The Globe
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Author : Pritpal S. Soorae
language : en
Publisher:
Release Date : 2013
Global Re Introduction Perspectives 2013 Further Case Studies From Around The Globe written by Pritpal S. Soorae and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Animals categories.
"This is the fourth issue in the Global Re-introduction Perspectives series and has been produced in the same standardized format as the previous three to maintain the style and quality. The casestudies are arranged in the following order: Introduction, Goals, Success Indicators, Project Summary, Major Difficulties Faced, Major Lessons Learned, Success of Project with reasons for success or failure. For the first issue I managed to collect 62 casestudies, the second issue 72 case-studies, the third issue 50 casestudies and this one 52 case-studies. These case studies in this issue cover the following taxa as follows: Invertebrates, Fish, Amphibians, Reptiles, Birds, Mammals, Plants... We hope the information presented in this book will provide a broad global perspective on challenges facing re-introduction projects trying to restore biodiversity."--Pritpal S. Soorae.
Biological Autonomy
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Author : Alvaro Moreno
language : en
Publisher: Springer
Release Date : 2015-05-19
Biological Autonomy written by Alvaro Moreno and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-19 with Philosophy categories.
Since Darwin, Biology has been framed on the idea of evolution by natural selection, which has profoundly influenced the scientific and philosophical comprehension of biological phenomena and of our place in Nature. This book argues that contemporary biology should progress towards and revolve around an even more fundamental idea, that of autonomy. Biological autonomy describes living organisms as organised systems, which are able to self-produce and self-maintain as integrated entities, to establish their own goals and norms, and to promote the conditions of their existence through their interactions with the environment. Topics covered in this book include organisation and biological emergence, organisms, agency, levels of autonomy, cognition, and a look at the historical dimension of autonomy. The current development of scientific investigations on autonomous organisation calls for a theoretical and philosophical analysis. This can contribute to the elaboration of an original understanding of life - including human life - on Earth, opening new perspectives and enabling fecund interactions with other existing theories and approaches. This book takes up the challenge.
Preservation Of Archives In Tropical Climates
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Author : René Teygeler
language : en
Publisher:
Release Date : 2001
Preservation Of Archives In Tropical Climates written by René Teygeler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Archival materials categories.