Risk Factors For Alzheimer S Disease
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Risk Factors For Alzheimer S Disease
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Author : Ines Moreno-Gonzalez
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-14
Risk Factors For Alzheimer S Disease written by Ines Moreno-Gonzalez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-14 with categories.
Diabetes Mellitus
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Author : Yusaku Nakabeppu
language : en
Publisher: Springer
Release Date : 2019-05-06
Diabetes Mellitus written by Yusaku Nakabeppu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-06 with Medical categories.
This book describes the precise mechanisms by which insulin resistance and diabetes mellitus (DM) act as risk factors for Alzheimer’s disease (AD). It opens by discussing the de novo synthesis of insulin in the brain and its functional significance with regard to glucose metabolism and maintenance of neuronal function in the brain. The epidemiological evidence that DM is a risk factor for the development of dementia, including AD as well as vascular dementia, is then examined. Subsequent chapters explore in depth the mechanisms involved in this relationship, including abnormal protein processing, dysregulated glucose metabolism, impaired insulin signaling, and mitochondrial dysfunction. The molecular interactions between diabetes and AD are fully discussed, highlighting the pathological molecular mechanisms induced by diabetes that promote and accelerate AD pathology. Finally, diagnostic biomarkers and potential therapeutic approaches for AD are considered on the basis of the presented evidence. In providing answers to the critical questions of whether and why DM is a risk factor for AD, this book will hold appeal for a wide interdisciplinary audience.
Alzheimer S Disease
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Author : Zaven S Khachaturian
language : en
Publisher: CRC Press
Release Date : 2019-06-04
Alzheimer S Disease written by Zaven S Khachaturian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.
Published in 1996: Alzheimer's disease is characterized by memory disturbances and changes in personality and is associated with aging, although it can occur in people under 65. It is a progressive disease, painful to witness as the patient's health declines. Alzheimer's Disease: Cause(s), Diagnosis, and Care, with its complete and authoritative discussions, will help you understand all facets of this complex disease. This book addresses a broad spectrum of topics ranging from diagnosis, causes, treatment, epidemiology, genetics, risk factors, and care and management. Alzheimer's Disease: Cause(s), Diagnosis, and Care is intended for a diverse audience, including practitioners and students, family members, and everyone who is concerned about this disease.
A Systematic Review Of Risk Factors For Alzheimer S Disease And Strategies For Prevention In China
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Author : Jingwen Tan
language : en
Publisher:
Release Date : 2017-01-26
A Systematic Review Of Risk Factors For Alzheimer S Disease And Strategies For Prevention In China written by Jingwen Tan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-26 with categories.
This dissertation, "A Systematic Review of Risk Factors for Alzheimer's Disease and Strategies for Prevention in China" by Jingwen, Tan, 谭靖雯, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Background: Alzheimer's disease, one type of dementia, is predicted to have great impact on society and economy. This effect increases rapidly especially in developing countries. The number of people with Alzheimer's disease is huge due to the large population in China where the effects of this disease are amplified by the one-child policy. Objective: To review the risk factors of Alzheimer's disease in different countries and offer some suggestions that how to prevent Alzheimer's Disease in China that has very limited research on Alzheimer's disease. To make recommendations for potential strategies to be implemented by policy-makers, government or other stakeholders. Method and results: Relevant studies which identified the risk factors for Alzheimer's disease and evaluated the interventions and treatments for reducing the risk of getting Alzheimer's disease, that were published between 1990 and 2012 were searched in PubMed and Google Academic using specific keywords. A total of 1071 studies were found and 62 used. Based on this systematic review, the risk factors of Alzheimer's disease are age, lifestyle, family history and genetics, vascular, mild cognitive impairment, head injury as well as early-life negative events. There appear to be several important contributions to Alzheimer's disease prevention including diet, cognitive activity, physical activity, social engagement, smoking cessation, and alcohol ingestion or simply being optimistic. Conclusion: This review has included the potential risk factors of Alzheimer's disease and the ways of preventing Alzheimer's disease, as well as to produce some possible strategies of preventing Alzheimer's disease based on the situation in China for the Chinese government and policy makers such as to use media as an important channel to draw people's attention about Alzheimer's disease and to educate about preventive factors. There should be government-funded education and health services in the rural areas and plans to build more leisure and sports centers in China. The government should also subsidize hospitals and medical centers to provide affordable or even free health examinations for people and build a central database for the purpose of recording, analysis and research into Alzheimer's disease for better understanding of the disease. Medical professionals and volunteers can help to enhance this database by the implementation of data collection to look for symptoms of Alzheimer's disease. If the patients appear to have such symptoms, further data collection should be taking place, such as family history of Alzheimer's disease, health status, head injuries, family status, characteristics and behavior, income levels, residential areas and other background information of the patients as part of their work whenever and wherever they go, especially in rural areas. DOI: 10.5353/th_b5098866 Subjects: Alzheimer's disease - China - Prevention Alzheimer's disease - Risk factors - China
Risk Factors For Alzheimer S Disease
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Author : Cornelia Marja van Duijn
language : en
Publisher:
Release Date : 1992
Risk Factors For Alzheimer S Disease written by Cornelia Marja van Duijn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Alzheimer's disease categories.
Risk Factors For Alzheimer S Disease
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Author : Cornelia M. van Duijn
language : en
Publisher:
Release Date : 1991
Risk Factors For Alzheimer S Disease written by Cornelia M. van Duijn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Alzheimer's disease categories.
Genetic Risk Factors In Alzheimer S Disease
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Author : Ágnes Fehér
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2011-01
Genetic Risk Factors In Alzheimer S Disease written by Ágnes Fehér and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01 with categories.
Alzheimer s disease is a progressive neurodegenerative disorder representing the most common type of dementia in the elderly population. According to the complex genetic model of late- onset, non-familial Alzheimer s disease, several heterogeneous susceptibility sets of genes may converge on the pathological processes that underlie the disease. Despite decades of intensive research the gene coding for apolipoprotein E is so far the only widely confirmed genetic risk factor for late- onset Alzheimer s disease. In this book we report the results of association studies investigating candidate gene variants supposed to be involved in Alzheimer s disease aetiology. Hypotheses regarding the role of the genes in the pathogenic pathways are discussed, taking into account the chromosomal localizations and the functions of the encoded proteins. As a long-term goal, identifying the genetic risk factors would help develop new strategies in the fields of prevention, diagnostics or genetics based pharmacology that can contribute to extend the lifespan and mental health of the elderly.
Alzheimer S Disease
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Author : Amy Borenstein
language : en
Publisher: Academic Press
Release Date : 2016-02-16
Alzheimer S Disease written by Amy Borenstein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-16 with Psychology categories.
Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest
Risk Factors For Alzheimer S Disease
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Author : Ines Moreno-Gonzalez
language : en
Publisher:
Release Date : 2020
Risk Factors For Alzheimer S Disease written by Ines Moreno-Gonzalez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Interaction Of Risk Factors In Alzheimer S Disease
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Author : Linda Drake Erickson
language : en
Publisher:
Release Date : 1987
Interaction Of Risk Factors In Alzheimer S Disease written by Linda Drake Erickson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.