Rna Computational Methods For Structure Kinetics And Rational Design Volume One
DOWNLOAD
Download Rna Computational Methods For Structure Kinetics And Rational Design Volume One PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Rna Computational Methods For Structure Kinetics And Rational Design Volume One book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Rna Computational Methods For Structure Kinetics And Rational Design Volume One
DOWNLOAD
Author : Peter G. Clote
language : en
Publisher: CRC Press
Release Date : 2025-03-20
Rna Computational Methods For Structure Kinetics And Rational Design Volume One written by Peter G. Clote and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-20 with Computers categories.
Comprising two volumes, RNA: Computational Methods for Structure, Kinetics, and Rational Design is a comprehensive treatment of computational methods concerning the secondary structure, folding kinetics and rational design of RNA. Volume One concerns energy and structure and is divided into five chapters. Chapter 1 describes the molecular structure of ribonucleotides, basic classes of RNA and databases of RNA sequences and structure. Chapter 2 presents the basic concepts of thermodynamics, since thermodynamics-based algorithms constitute an essential tool in rational design of functional RNA molecules. Chapter 3 describes how empirical secondary structure energy parameters are obtained from ultraviolet absorbance experiments via Van 't Hoff plots and least-squares data fitting. Chapter 4 describes methods from combinatorics, automata and formal language theory, and complex analysis. Chapter 5 provides an overview of some of the most important thermodynamics-based algorithms related to secondary structure. Exercises and solutions are provided at the end of every chapter and source code is available at the book's website (sometimes including computer programs using Python and extensions Numpy and Scipy). This book provides the nuts, bolts and tools to take the next steps in computational RNA synthetic biology. It is perfect for advanced undergraduate, graduate and post-graduate readers having analytical interests and skills from areas such as physical chemistry, physics, mathematics, computer science, and statistics.
Machine Learning In Bioinformatics
DOWNLOAD
Author : Yanqing Zhang
language : en
Publisher: John Wiley & Sons
Release Date : 2009-02-23
Machine Learning In Bioinformatics written by Yanqing Zhang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-23 with Computers categories.
An introduction to machine learning methods and their applications to problems in bioinformatics Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. From an internationally recognized panel of prominent researchers in the field, Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics. Coverage includes: feature selection for genomic and proteomic data mining; comparing variable selection methods in gene selection and classification of microarray data; fuzzy gene mining; sequence-based prediction of residue-level properties in proteins; probabilistic methods for long-range features in biosequences; and much more. Machine Learning in Bioinformatics is an indispensable resource for computer scientists, engineers, biologists, mathematicians, researchers, clinicians, physicians, and medical informaticists. It is also a valuable reference text for computer science, engineering, and biology courses at the upper undergraduate and graduate levels.
Advances In Protein Molecular And Structural Biology Methods
DOWNLOAD
Author : Timir Tripathi
language : en
Publisher: Academic Press
Release Date : 2022-01-14
Advances In Protein Molecular And Structural Biology Methods written by Timir Tripathi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-14 with Science categories.
Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. - Presents a thorough overview of the latest and emerging methods and technologies for protein study - Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy - Includes computational and machine learning methods - Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
Encyclopedia Of Bioinformatics And Computational Biology
DOWNLOAD
Author :
language : en
Publisher: Elsevier
Release Date : 2018-08-21
Encyclopedia Of Bioinformatics And Computational Biology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-21 with Medical categories.
Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases
Current Developments In Biotechnology And Bioengineering
DOWNLOAD
Author : R. D. Tyagi
language : en
Publisher: Elsevier
Release Date : 2020-03-31
Current Developments In Biotechnology And Bioengineering written by R. D. Tyagi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-31 with Technology & Engineering categories.
Current Developments in Biotechnology and Bioengineering: Environmental and Health Impact of Hospital Wastewater narrates the origin (history) of pharmaceuticals discoveries, hospital wastewater and its environmental and health impacts. It covers microbiology of hospital wastewater (pathogens, multi-drug resistance development, microbial evolution and impacts on humans, animals, fish), advanced treatment options (including biological, physical and chemical methods), and highlights aspects required during hospital wastewater treatment processes. This book provides an amalgamation of all recent scientific information on hospital wastewater which is not available in the current literature. - Introduces physical, chemical and molecular testing methods for the analysis and characterization of hospital wastewater - Discusses the environmental impact and health hazards of hospital wastewater - Describes the microbiological aspects of the hospital wastewater, like microbial community, metagenomics, pathogens, VBNC and mechanism of antibiotic resistance development - Explains hospital wastewater and its role in microbial evolution - Highlights future treatment options, guidelines and drug disposal tactics
Explorations In Computational Physics
DOWNLOAD
Author : Devang Patil
language : en
Publisher: Educohack Press
Release Date : 2025-02-20
Explorations In Computational Physics written by Devang Patil and has been published by Educohack Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-20 with Science categories.
"Explorations in Computational Physics" delves into the intricate world of computational physics, offering a comprehensive guide from fundamental theories to cutting-edge applications. This book serves as an indispensable companion for both novice learners and seasoned researchers. We cover a diverse array of topics, meticulously unfolding layers of computational techniques and their applications in various branches of physics. From classical mechanics simulations elucidating celestial mechanics to quantum mechanics computations unraveling atomic and subatomic realms, the book navigates through the vast landscape of computational methodologies with clarity and precision. Furthermore, we delve into electromagnetic field simulations, statistical mechanics, and thermodynamics, equipping readers with tools to model complex physical phenomena with accuracy and efficiency. High-performance computing techniques, data analysis, and visualization methodologies are elucidated, empowering readers to harness modern computational resources in their research. With lucid explanations, illustrative examples, and insightful discussions on emerging technologies like quantum computing and artificial intelligence, "Explorations in Computational Physics" fosters a deeper understanding of computational methodologies and their transformative impact on physics research.
Molecular Robotics
DOWNLOAD
Author : Satoshi Murata
language : en
Publisher: Springer Nature
Release Date : 2022-08-17
Molecular Robotics written by Satoshi Murata and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-17 with Technology & Engineering categories.
In this book, researchers at the forefront of the field explain the minimum necessary background knowledge and introduce important topics in molecular robotics in an easy-to-understand manner.Molecular robotics is related to many fields, such as systems engineering, control engineering, computer science, biochemistry, biophysics, polymer chemistry, nucleic acid chemistry, molecular biology, and ethics. The whole picture of molecular robotics can be grasped only by looking at these fields from a bird's-eye view. This book has been planned in the belief that such a book is essential for students and those new to the field to understand the ongoing expansion of molecular robotics.The book consists of eight chapters: introduction, design theory of molecular robots, systemization technology, molecular nanotechnology, molecular actuators, molecular materials, medical applications, and social acceptance. In each chapter, the reader can get a general idea of the theory, underlying technology, medical applications, and social issues, and can also understand what is currently being done on the research front. In addition, there are many parts that introduce topics related to molecular robotics.
Frontiers In Computational And Systems Biology
DOWNLOAD
Author : Jianfeng Feng
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-06-14
Frontiers In Computational And Systems Biology written by Jianfeng Feng and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-14 with Science categories.
Biological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician’s fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most common genetic variants as well as rare variants of the human DNA that may alter individual’s susceptibility to disease and the response to medical treatment. Meanwhile the multi-electrode recording from behaving animals makes it feasible to control the animal mental activity, which could potentially lead to the development of useful brain–machine interfaces. - bracing the sheer volume of genetic, genomic, and other type of data, an essential approach is, ?rst of all, to avoid drowning the true signal in the data. It has been witnessed that theoretical approach to biology has emerged as a powerful and st- ulating research paradigm in biological studies, which in turn leads to a new - search paradigm in mathematics, physics, and computer science and moves forward with the interplays among experimental studies and outcomes, simulation studies, and theoretical investigations.
Biotechnology For Biofuel Production And Optimization
DOWNLOAD
Author : Carrie A Eckert
language : en
Publisher: Elsevier
Release Date : 2016-01-19
Biotechnology For Biofuel Production And Optimization written by Carrie A Eckert and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-19 with Science categories.
Biotechnology for Biofuel Production and Optimization is the compilation of current research findings that cover the entire process of biofuels production from manipulation of genes and pathways to organisms and renewable feedstocks for efficient biofuel production as well as different cultivation techniques and process scale-up considerations. This book captures recent breakthroughs in the interdisciplinary areas of systems and synthetic biology, metabolic engineering, and bioprocess engineering for renewable, cleaner sources of energy. - Describes state-of-the-art engineering of metabolic pathways for the production of a variety of fuel molecules - Discusses recent advances in synthetic biology and metabolic engineering for rational design, construction, evaluation of novel pathways and cell chassis - Covers genome engineering technologies to address complex biofuel-tolerant phenotypes for enhanced biofuel production in engineered chassis - Presents the use of novel microorganisms and expanded substrate utilization strategies for production of targeted fuel molecules - Explores biohybrid methods for harvesting bioenergy - Discusses bioreactor design and optimization of scale-up
Methods For Studying Nucleic Acid Drug Interactions
DOWNLOAD
Author : Meni Wanunu
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Methods For Studying Nucleic Acid Drug Interactions written by Meni Wanunu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on the availability of analytical methods that assess the eff