Rna Delivery Function For Anticancer Therapeutics
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Rna Delivery Function For Anticancer Therapeutics
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Author : Loutfy H. Madkour
language : en
Publisher: CRC Press
Release Date : 2022-01-25
Rna Delivery Function For Anticancer Therapeutics written by Loutfy H. Madkour and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-25 with Science categories.
This book presents an overview of the current status of translating the RNAi cancer therapeutics in the clinic, a brief description of the biological barriers in drug delivery, and the roles of imaging in aspects of administration route, systemic circulation, and cellular barriers for the clinical translation of RNAi cancer therapeutics, and with partial content for discussing the safety concerns. It then focuses on imaging-guided delivery of RNAi therapeutics in preclinical development, including the basic principles of different imaging modalities, and their advantages and limitations for biological imaging. With growing number of RNAi therapeutics entering the clinic, various imaging methods will play an important role in facilitating the translation of RNAi cancer therapeutics from bench to bedside. RNAi technique has become a powerful tool for basic research to selectively knock down gene expression in vitro and in vivo. Our scientific and industrial communities have started to develop RNAi therapeutics as the next class of drugs for treating a variety of genetic disorders, such as cancer and other diseases that are particularly hard to address with current treatment strategies. Key Features Provides insight into the current advances and hurdles of RNAi therapeutics. Accelerates RNAi, miRNAs, and siRNA drug development for cancer therapy from bench to bedside. Addresses various modifications and novel delivery strategies for miRNAs, piRNAs and siRNA delivery in anticancer therapeutics. Explores the need for the interaction of hematologists,cell biologists, immunologists, and material scientists in the development of novel cancer therapies. Describes the current status of clinical trials related to miRNA and siRNA-based cancer therapy Presents remaining issues that need to be overcome to establish successful therapies.
Rna Delivery Function For Anticancer Therapeutics
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Author : Loutfy H. Madkour
language : en
Publisher: CRC Press
Release Date : 2022-01-26
Rna Delivery Function For Anticancer Therapeutics written by Loutfy H. Madkour and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-26 with Science categories.
This book presents an overview of the current status of translating the RNAi cancer therapeutics in the clinic, a brief description of the biological barriers in drug delivery, and the roles of imaging in aspects of administration route, systemic circulation, and cellular barriers for the clinical translation of RNAi cancer therapeutics, and with partial content for discussing the safety concerns. It then focuses on imaging-guided delivery of RNAi therapeutics in preclinical development, including the basic principles of different imaging modalities, and their advantages and limitations for biological imaging. With growing number of RNAi therapeutics entering the clinic, various imaging methods will play an important role in facilitating the translation of RNAi cancer therapeutics from bench to bedside. RNAi technique has become a powerful tool for basic research to selectively knock down gene expression in vitro and in vivo. Our scientific and industrial communities have started to develop RNAi therapeutics as the next class of drugs for treating a variety of genetic disorders, such as cancer and other diseases that are particularly hard to address with current treatment strategies. Key Features Provides insight into the current advances and hurdles of RNAi therapeutics. Accelerates RNAi, miRNAs, and siRNA drug development for cancer therapy from bench to bedside. Addresses various modifications and novel delivery strategies for miRNAs, piRNAs and siRNA delivery in anticancer therapeutics. Explores the need for the interaction of hematologists,cell biologists, immunologists, and material scientists in the development of novel cancer therapies. Describes the current status of clinical trials related to miRNA and siRNA-based cancer therapy Presents remaining issues that need to be overcome to establish successful therapies.
Advances In Medical Biochemistry Genomics Physiology And Pathology
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Author : Raj Bawa
language : en
Publisher: CRC Press
Release Date : 2021-12-22
Advances In Medical Biochemistry Genomics Physiology And Pathology written by Raj Bawa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Medical categories.
The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand‐alone text that provides a broad survey of various critical topics—all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. While bridging the gap between basic research and clinical medicine, this series provides a thorough understanding of medicine’s potential to address health problems from both the patient’s and the provider’s perspectives in a healthcare setting. The range of topics covered and the expertise of the contributing authors accurately reflect the rapidly evolving areas within medicine—from basic medical sciences to clinical specialties. Each volume is essential reading for physicians, medical students, nurses, fellows, residents, undergraduate and graduate students, educators, policymakers, and biomedical researchers. The multidisciplinary approach of the series makes it a valuable reference resource for the pharmaceutical industry, academia, and governments. However, unlike other series on medicine or medical textbooks, this series focuses on current trends, perspectives, and issues in medicine that are central to healthcare delivery in the 21st century. Volume 1 focuses on the current issues in basic medical sciences, subjects that are fundamental to the practice of medicine. Specifically, it covers medical biochemistry, genomics, physiology, and pathology. These subjects, traditionally taught in the first two years of medical school that precede clinical instruction, provide a core of basic knowledge critical to the success in clinical medicine during rotations, training, and medical practice.
Polymeric Nanoparticles As A Promising Tool For Anti Cancer Therapeutics
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Author : Prashant Kesharwani
language : en
Publisher: Academic Press
Release Date : 2019-06-25
Polymeric Nanoparticles As A Promising Tool For Anti Cancer Therapeutics written by Prashant Kesharwani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-25 with Medical categories.
Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. - Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy - Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer - Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles
New Advances In Rna Targeting
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Author : Olga N. Ilinskaya
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-04
New Advances In Rna Targeting written by Olga N. Ilinskaya and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-04 with RNA targeting categories.
Long Non Coding Rnas In Human Disease
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Author : Kevin V. Morris
language : en
Publisher: Springer
Release Date : 2016-04-13
Long Non Coding Rnas In Human Disease written by Kevin V. Morris and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-13 with Medical categories.
This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.
Anticancer Therapeutics
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Author : Sushil Kumar Upadhyay
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2024-12-16
Anticancer Therapeutics written by Sushil Kumar Upadhyay and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-16 with Science categories.
The book provides a strong platform for delineating the complex mechanism underlying cancer therapeutics along with the therapies countering drug resistance. It describes tumor angiogenesis and cancer metastasis, oncogenes and oncogenesis. It covers natural phytochemicals and herbal nanomedicines. It includes the recent advances in nanocomposite films and SiRNA-mediated drug delivery. Cancer biology, mechanistic insight and therapeutics. Valuable source about nanomedicine design, nano-based drug delivery systems and approaches for cancer therapy.
Carbon Based Nanomaterials For Sustainable And Technological Applications
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Author : Loutfy H. Madkour
language : en
Publisher: CRC Press
Release Date : 2024-10-29
Carbon Based Nanomaterials For Sustainable And Technological Applications written by Loutfy H. Madkour and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-29 with Science categories.
Carbon-Based Nanomaterials for Sustainable and Technological Applications covers the fundamentals of carbon-based nanomaterials (CNMs) and their potential for technological and industrial applications. Addressing recent advancements in technology and improvement in material synthesis, the book outlines how functionalized CNMs are used in nanobiotechnology, for active sorbent materials, and in pharmaceutical applications. Chapters cover macro-scale applications, biosensors and drug delivery, and treatment in cancer and coronavirus diseases. Key features: Through up-to-date references, this book demonstrates that carbon-based nanomaterials are one of the most promising nanomaterials in medical applications, such as drug and gene delivery carriers, as well as nonmedical, environmental applications. Discusses the synthesis methods of processing (CQDs), (GQDs), (CPDs), and (g-C3N4) materials-based nanocomposites for biotechnological applications. Chapters address various classes of carbon nanomaterials and their innovative technologies. Opens up further exploration of environmental nanotechnology, bionanotechnology, and biomedical applications of novel carbon nanomaterials. Full references can be found via the Support Material: www.routledge.com/9781032635934. Written by a leading expert, this volume provides the reader with thorough coverage of bionanotechnology and biomedical applications of novel carbon nanomaterials.
Targeted Delivery Of Small And Macromolecular Drugs
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Author : Ajit S. Narang
language : en
Publisher: CRC Press
Release Date : 2010-05-12
Targeted Delivery Of Small And Macromolecular Drugs written by Ajit S. Narang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-12 with Medical categories.
Site-specific drug delivery and targeting attracts much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Focusing on the delivery technologies that utilize both systemic and local rou
World Scientific Encyclopedia Of Nanomedicine And Bioengineering I The Nanotechnology For Translational Medicine Tissue Engineering Biological Sensing Medical Imaging And Therapeutics A 4 Volume Set
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Author :
language : en
Publisher: World Scientific
Release Date : 2016-08-30
World Scientific Encyclopedia Of Nanomedicine And Bioengineering I The Nanotechnology For Translational Medicine Tissue Engineering Biological Sensing Medical Imaging And Therapeutics A 4 Volume Set written by and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-30 with Technology & Engineering categories.
This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine.An important aspect of this book set is the introduction of nanotechnology to the medical communities that are searching for new treatments of cancer. It may also break the barriers between the physical and medical sciences so that more MDs will be able to appreciate the new discoveries and establishments in medical diagnosis and therapy that will allow the effective handling of major clinical issues.This major reference publication will be important as the field of nanomedicine has been rapidly developing with a great deal of new information. It is anticipated that the research will soon advance into the pre-clinical stage. Therefore, this reference set can serve as valuable background information for future clinical studies.