Role Of Diastolic Arterial Pressure In Microstructural Changes Of The Brain In Patients With Hypertension Related Cerebral Small Vessel Disease
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Role Of Diastolic Arterial Pressure In Microstructural Changes Of The Brain In Patients With Hypertension Related Cerebral Small Vessel Disease
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Author : Elena V. Gnedovskaya
language : en
Publisher:
Release Date : 2017
Role Of Diastolic Arterial Pressure In Microstructural Changes Of The Brain In Patients With Hypertension Related Cerebral Small Vessel Disease written by Elena V. Gnedovskaya and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Introduction. The usage of modern antihypertensive drugs improved the course of arterial hypertension (AH), but did not lead to the expected reduction in the incidence of small vessel disease (SVD) and its complications. This fact encourages further investigation of the mechanisms of hypertension-related brain damage.Objective: Evaluation of the relation between daily profile of blood pressure (BP) and microstructure changes of the brain in patients with SVD and AH.Material and methods. The study included 64 patients (mean age 59.4u00b15.4 years, 38 (59,4%) female) with SVD and AH. All patients received antihypertensive drugs. Ambulatory blood pressure monitoring (ABPM) and diffusion MRI with region of interest analysis of diffusion coefficient according to different maps for all participants. The relation between parameters was estimated using multivariate linear regression.Results. A statistically significant relation was found between daily profile of BP according to ABPM and microstructure abnormalities of the juxtacortical white matter hyperintensity (WMH) of anterior and posterior frontal lobes according to MRI data. An increase in diastolic blood pressure (DBP) and its variability were of predominant importance in increasing in mean and radial diffusivity.Conclusion. The revealed relations evidence to importance of the increase and variability of DBP to brain damage in patients with SVD and AH. u041cicrostructural abnormalities seems to correspond to an increase in the diffusion of free water and damage to myelin suggesting an increase in permeability of the blood-brain barrier and the development of vasogenic edema in areas of WMH in patients with SVD and AH.
Cerebral Small Vessel Disease
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Author : Leonardo Pantoni
language : en
Publisher: Cambridge University Press
Release Date : 2014-05
Cerebral Small Vessel Disease written by Leonardo Pantoni and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05 with Medical categories.
Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
Cerebral Microbleeds
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Author : David J. Werring
language : en
Publisher: Cambridge University Press
Release Date : 2011-05-26
Cerebral Microbleeds written by David J. Werring and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-26 with Medical categories.
Stroke is a leading cause of death and disability throughout the world. About one in three symptomatic strokes are due to disease of small perforating arteries; however, most effective interventions are targeted at disease of large arteries. The underlying mechanisms and treatment of small vessel disease remain poorly understood. Microbleeds have emerged as a critical imaging marker of small vessel disease, being found in all types of stroke. With increasing evidence that microbleeds are caused by hypertensive arteriopathy and cerebral amyloid angiopathy, they are likely to play a strong future role in increasing our understanding of the causes of small vessel disease and the potential link between cerebrovascular disease and neurodegeneration. Cerebral Microbleeds summarizes our current knowledge, bringing together expert research from global authorities in the field. This authoritative and systematic text will be of interest to all clinical researchers and physicians in the fields of stroke and cognitive impairment.
Cerebral Small Vessel Diseases From Vessel Alterations To Cortical Parenchymal Injury
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Author : Andreas Charidimou
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-12
Cerebral Small Vessel Diseases From Vessel Alterations To Cortical Parenchymal Injury written by Andreas Charidimou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-12 with categories.
Factors Affecting Neurological Aging
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Author : Colin R Martin
language : en
Publisher: Academic Press
Release Date : 2021-06-01
Factors Affecting Neurological Aging written by Colin R Martin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-01 with Psychology categories.
Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease. Provides the most comprehensive coverage on a broad range of topics related to the neuroscience of aging Features sections on the genetic components that influence aging and diseases of aging Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations Includes more than 500 illustrations and tables
Geriatric Gastroenterology
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Author : C. S. Pitchumoni
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-26
Geriatric Gastroenterology written by C. S. Pitchumoni and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-26 with Medical categories.
As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.
Cerebral Blood Flow
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Author :
language : en
Publisher: Elsevier
Release Date : 1972-01-01
Cerebral Blood Flow written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972-01-01 with Medical categories.
Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.
The Role Of Transcranial Doppler Sonography In The Management Of Pediatric Hydrocephalus
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Author : Branislav Kolarovszki
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-11-06
The Role Of Transcranial Doppler Sonography In The Management Of Pediatric Hydrocephalus written by Branislav Kolarovszki and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Medical categories.
Negative influence of cerebral circulation with the emergence of cerebral hypoperfusion plays a significant role in the pathophysiology of pediatric hydrocephalus. Transcranial Doppler sonography is a non-invasive method for indirectly measuring intracranial pressure and decreasing intracranial compliance by assessing changes of cerebral circulation. This book discusses the cerebral circulation and intracranial dynamics in pediatric hydrocephalus. It also focuses on evaluating the impact of various intracranial factors on Doppler parameters of cerebral circulation, especially in neonates with hydrocephalus. The ambition of this work is to improve indication and timing of drainage procedure in children with hydrocephalus by applying scientific results and clinical experience.
Cutting Edge Approaches For Cns Protection And Repair Focus On Vascular And Degenerative Disorders
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Author : Johannes Boltze
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-19
Cutting Edge Approaches For Cns Protection And Repair Focus On Vascular And Degenerative Disorders written by Johannes Boltze and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-19 with Science categories.
Magnetoencephalography
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Author : Selma Supek
language : en
Publisher: Springer
Release Date : 2014-08-07
Magnetoencephalography written by Selma Supek and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-07 with Technology & Engineering categories.
Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.