Role Of Exosomes In Biological Communication Systems
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Role Of Exosomes In Biological Communication Systems
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Author : Faisal A. Alzahrani
language : en
Publisher: Springer Nature
Release Date : 2020-11-20
Role Of Exosomes In Biological Communication Systems written by Faisal A. Alzahrani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-20 with Medical categories.
This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.
Diagnostic And Therapeutic Applications Of Exosomes In Cancer
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Author : Mansoor M. Amiji
language : en
Publisher: Academic Press
Release Date : 2018-05-11
Diagnostic And Therapeutic Applications Of Exosomes In Cancer written by Mansoor M. Amiji and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-11 with Medical categories.
Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer.
Exosomes In Brain Health And Disease
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Author : Konstantin Glebov
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-06
Exosomes In Brain Health And Disease written by Konstantin Glebov and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-06 with Science categories.
Extracellular Vesicles As Matrix Messengers
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Author : Kirsi Rilla
language : en
Publisher: Springer Nature
Release Date : 2024-11-05
Extracellular Vesicles As Matrix Messengers written by Kirsi Rilla and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-05 with Science categories.
The cells in our body release a wide variety of factors into the extracellular space that help to signal, regulate and build the extracellular matrix. One of the most fascinating of these factors are extracellular vesicles (EVs). These lipid membrane-covered particles have now emerged as a new powerful method of near and distant intercellular communication. EVs facilitate communication between cells and their extracellular environment, which includes solid tissues and body fluids. This volume summarizes current knowledge on EVs as integral and active components of the extracellular matrix. It covers topics such as the interplay between EVs and ECM molecules and how cancer cells modify their microenvironment by releasing EVs. Additionally, it discusses how EVs can mediate tissue repair and regeneration by modulating matrix degradation, protein cross-linking, and matrix calcification. The book explores instances where EVs play a crucial role in conditions related to matrix biology, such as cancer and arthritis, and considers their potential as therapeutic agents for these medical conditions. Both experienced researchers and clinicians, as well as PhD students who wish to study the extracellular matrix and extracellular vesicles will find this book is an excellent introduction into the field of EV biology with applications in matrix research. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
The Biology And Therapeutic Application Of Mesenchymal Cells 2 Volume Set
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Author : Kerry Atkinson
language : en
Publisher: John Wiley & Sons
Release Date : 2017-01-17
The Biology And Therapeutic Application Of Mesenchymal Cells 2 Volume Set written by Kerry Atkinson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-17 with Science categories.
The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues. Provides coverage on both the biology of mesenchymal stem cells and stromal cells, and their therapeutic applications Describes the therapeutic potential of mesenchymal stem and stromal cells in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models Discusses the current status of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues Written and edited by leaders in the field The Biology and Therapeutic Application of Mesenchymal Cells is an invaluable resource for those studying stem cells, cell biology, genetics, gene or cell therapy, or regenerative medicine.
Gestational Diabetes
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Author : Luis Sobrevia
language : en
Publisher: BoD – Books on Demand
Release Date : 2013-04-24
Gestational Diabetes written by Luis Sobrevia and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-24 with Medical categories.
This book summarizes several aspects of GD, which is caused by not well-understood multifactorial mechanisms. Common strategies seem to be key in the understanding of the syndrome, i.e., endothelial dysfunction and the role of other placenta cells such as trophoblasts. It is a book that will definitively help to increase the knowledge-based management of GD for the well being of the mother and the fetus. Several chapters lead us to the conclusion that pre-pregnancy and antenatal screening of women is required, something that will improve the management and outcome of a current pregnancy but will also optimize life-long health and well being considering the inter-generational consequences.
Advances In Cell And Gene Therapy In Treating Neural Diseases
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Author : Raymond Ching-Bong Wong
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-07
Advances In Cell And Gene Therapy In Treating Neural Diseases written by Raymond Ching-Bong Wong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-07 with Science categories.
Exosomes Based Drug Delivery Strategies For Brain Disorders
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Author : Neeraj Mishra
language : en
Publisher: Springer Nature
Release Date : 2024-03-30
Exosomes Based Drug Delivery Strategies For Brain Disorders written by Neeraj Mishra and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-30 with Science categories.
This book provides a comprehensive overview of the role of exosomes in brain diseases, including stroke, multiple sclerosis, Parkinson's disease, Alzheimer's disease, epilepsy, and depression. It covers the basics of exosome biogenesis, composition, and synthesis, as well as the therapeutic potential of exosomes in brain disorders. The correlation between exosomes and neuroinflammation, the challenges of using exosomes as a novel carrier, and engineered exosomes to deliver therapeutic protein are covered well in this book. Use of radiolabelled exosomes as a diagnostic tool and the toxicity studies of exosomes with potential overcome approaches. It is an essential resource for researchers, clinicians, and healthcare professionals working in the field of exosome research, especially on its applications in brain disorders.
Editors Showcase Chemical Biology
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Author : John D. Wade
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-23
Editors Showcase Chemical Biology written by John D. Wade and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-23 with Science categories.
Extracellular Vesicle Biology And Translational Application
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Author : Zongjin Li
language : en
Publisher: Springer Nature
Release Date : 2024-12-11
Extracellular Vesicle Biology And Translational Application written by Zongjin Li and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-11 with Medical categories.
This book focuses on the applications of extracellular vesicles (EVs) for regenerative medicine. EVs are small, lipid-bound vesicles carrying cargo that can be released by virtually all cell types. Over the past decades, the field of EV research has experienced exponential growth. Once dismissed as mere cellular debris, EVs are now recognized as sophisticated messengers, facilitating the transmission of crucial information between cells and orchestrating a myriad of biological processes. Notably, stem cell-derived EVs hold particular promise in regenerative therapeutic applications. Rich in the functional components of stem cells, these EVs offer an alternative approach to cell therapy for tissue repair and regeneration. The purpose of this book is to provide an overview of EVs on their biology, function, and potential applications. The book starts with exploring the intricate biology of EVs, their cargo, and their unique ability to modulate cellular processes. It discusses the therapeutic potential of EVs in various diseases, as well as the approaches for the bionanotechnological development of artificial EVs for theranostics. Large-scale EV isolation methods and their preclinical applications are also addressed. It will be useful for undergraduate and graduate students in medicine and cell biology, biologist, and others who are interested in such topic.