Role Of Nutraceuticals In Cancer Chemosensitization


Role Of Nutraceuticals In Cancer Chemosensitization
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Role Of Nutraceuticals In Cancer Chemosensitization


Role Of Nutraceuticals In Cancer Chemosensitization
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-10-18

Role Of Nutraceuticals In Cancer Chemosensitization written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-18 with Medical categories.


Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresistance, such as curcumin, resveratrol, indole 3-carbinol, tocotrienols, ursolic acid, fisetin, celastrol, gambogic, butein, catechins and silymarin. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use nutraceuticals as a sensitizing agent for chemotherapy. Brings updated information on natural compounds used as specific inhibitors of cell signaling pathways as reviewed by experts in the field Presents experts analysis and summary of reported and novel findings and potential translational application in cancer patients Describes molecular mechanisms with new and helpful approaches for the readers to use in their own investigations



Advances In Nutraceutical Applications In Cancer Recent Research Trends And Clinical Applications


Advances In Nutraceutical Applications In Cancer Recent Research Trends And Clinical Applications
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Author : Sheeba Varghese Gupta
language : en
Publisher: CRC Press
Release Date : 2019-10-23

Advances In Nutraceutical Applications In Cancer Recent Research Trends And Clinical Applications written by Sheeba Varghese Gupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-23 with Medical categories.


Dietary supplements and nutraceuticals such as Vitamin A and D, Omega-3 and probiotics are used as part of the cancer treatment as complimenting the main therapy. Several Nutraceuticals have shown to boost the immune responses, while emerging clinical studies and other research suggests that some plant-based agents may, indeed, impact late-stage cancer, influencing molecular processes corrupted by tumor cells to evade detection, expand clonally, and invade surrounding tissues. Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications is an attempt to collect evidence and related clinical information of application of Nutraceuticals to be used in cancer treatment or compliment the cancer treatment. It contains 16 chapters written by experts in related field’s and covers many different aspects of the formulation and development of Nutraceuticals for cancer applications. This book covers efficacy, safety and toxicological aspects of nutraceuticals. It also addresses various novel drug delivery systems of nutraceuticals with anticancer properties, as well as nutraceuticals as supplements for cancer prevention. Features: Offers a comprehensive view of neutraceuticals’ role in cancer prevention and treatment Covers the applications and implications of neutraceuticals in prostate, colorectal, breast and gynecological cancers Discusses the principles of neutrigenomics and neutrigenetics in cancer prevention Explors the role of probiotics and micronutrients in cancer treatment and prevention Nutraceuticals can alter the gut microbiota. Gut microbiome undergoes changes during the disease status and followed by the cancer treatment. Nutraceutical’s role in proliferation and prevention of gynecological cancers, nutraceutical’s role in proliferation and prevention of prostate cancer and role of micronutrients in cancer prevention, both pros and cons, are some of the topics discussed in various chapters in this book. This book is addressed to scientists, clinicians, and students who are working in the area of Nutraceutical applications in cancer treatment.



Nutraceuticals And Cancer


Nutraceuticals And Cancer
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Author : Fazlul H. Sarkar
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-22

Nutraceuticals And Cancer written by Fazlul H. Sarkar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-22 with Medical categories.


This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be mediated through alterations in multiple molecular targets. This book contains sixteen chapters which begin with historical perspective on the value of natural agents in the prevention of human malignancies followed by a series of current topics on multiple nutraceuticals targeting multiple cancers. This collection would likely be useful for bringing newer generations with broader perspectives in launching cutting-edge innovative molecular research, which would certainly help in designing targeted clinical trials in order to realize the dream of customize strategies for the prevention and/or treatment of human malignancies without causing any systemic toxicity. Moreover, the knowledge gained would allow novel utilization of nutraceuticals as adjunct to both conventional chemotherapy and radiation therapy in order to improve the overall quality of life and survival of patients diagnosed with cancers.



Nutraceuticals And Cancer Signaling


Nutraceuticals And Cancer Signaling
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Author : Seid Mahdi Jafari
language : en
Publisher: Springer Nature
Release Date : 2021-09-24

Nutraceuticals And Cancer Signaling written by Seid Mahdi Jafari and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-24 with Medical categories.


Today's consumers are looking for food products with health-promoting roles in addition to nutritional benefits. With current research showing that nutraceuticals and functional foods rich in specific bioactives may have chemopreventative effects, these products are increasingly popular. However, while much in the literature supports the health-promoting features of these foods, few texts focus on their bioactive agents and their mode of action in cancer signaling. Nutraceuticals and Cancer Signalling: Clinical Aspects and Mode of Action explains the link between nutraceuticals and cancer in terms of clinical trials and modes of action. This book gives an overview of common cancers and their mechanisms, and the most common functional foods and their bioactive components. Individual chapters focus on specific functional foods--including tomatoes, garlic, honey, tea, yoghurt, and many more--their prominent bioactive compounds, and their mode of action in cancer signaling and chemoprevention. Recent findings on cancer-prevention roles of different vitamins and minerals are also discussed. For food scientists, nutritionists, and pharmaceutical experts looking to understand how functional foods can play a role in fighting cancer, this text serves as a one-stop reference.



Nutraceuticals And Cancer


Nutraceuticals And Cancer
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Author : Fazlul H. Sarkar
language : en
Publisher: Springer
Release Date : 2011-11-30

Nutraceuticals And Cancer written by Fazlul H. Sarkar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-30 with Medical categories.


This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be mediated through alterations in multiple molecular targets. This book contains sixteen chapters which begin with historical perspective on the value of natural agents in the prevention of human malignancies followed by a series of current topics on multiple nutraceuticals targeting multiple cancers. This collection would likely be useful for bringing newer generations with broader perspectives in launching cutting-edge innovative molecular research, which would certainly help in designing targeted clinical trials in order to realize the dream of customize strategies for the prevention and/or treatment of human malignancies without causing any systemic toxicity. Moreover, the knowledge gained would allow novel utilization of nutraceuticals as adjunct to both conventional chemotherapy and radiation therapy in order to improve the overall quality of life and survival of patients diagnosed with cancers.



Functional Foods For Health Maintenance Understanding Their Role In Cancer Prevention


Functional Foods For Health Maintenance Understanding Their Role In Cancer Prevention
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Author : Saroj Arora
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-08-31

Functional Foods For Health Maintenance Understanding Their Role In Cancer Prevention written by Saroj Arora and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-31 with Medical categories.


The comprehensive information about the inverse relationship between the incidence of cancer and the consumption of natural food has impacted our understanding of the biochemical mechanisms behind cancer and its treatment. Functional Foods for Health Maintenance: Understanding their Role in Cancer Prevention is a review of pre-clinical studies unraveling the chemotherapeutic potential of phytochemicals and other food sources. The editors attempt to summarize the evidence, methods and techniques for identifying specific nutraceuticals and foods capable of interfering and reducing the risk of cancer. The book compiles 19 edited chapters that cover the chemopreventive effects of different phytochemicals, animal and stem cell models for cancer prevention, and novel nanotechnology-based nutraceuticals. The contributors have also highlighted the techniques employed for the detection of cancer with a review on cancer biomarkers. The book is a resource for post-graduate students and researchers working in the field of nutrition, molecular biology, chemoprevention, biochemistry and pharmaceutical sciences.



Cancer Cell Chemoresistance And Chemosensitization


Cancer Cell Chemoresistance And Chemosensitization
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Author : Kunnumakkara Ajaikumar B
language : en
Publisher: World Scientific
Release Date : 2018-02-13

Cancer Cell Chemoresistance And Chemosensitization written by Kunnumakkara Ajaikumar B and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-13 with Medical categories.


Despite the significant advances in cancer therapy made through constant evaluation and analysis of treatment aftereffects, the disease still remains one of the foremost causes of mortality worldwide killing more than 12 million people annually. The prime reason behind the failure of conventional chemotherapeutics which are used as the chief regimen in the comprehensive treatment of cancers is the development of chemoresistance. It can be either intrinsic or acquired and is primarily mediated via different key regulators like MDR, MAPK, NF-κB, PI3K/Akt, Wnt signaling pathways etc. Thus, agents which can target these regulatory elements or pathways and in turn sensitize cancer cells to chemotherapy holds immense prospect. However, there is barely such comprehensive work available in scientific literature that explains how chemosensitization of cancer cells functions using different drug combinations and exhibit synergism. This book provides a detailed description of chemoresistance and chemosensitization, targets for chemosensitization and various approaches adapted in the process of chemosensitization. Furthermore, the book explicates the role of various chemosensitizers, both natural and synthetic in sensitizing cancer cells and also details the current research findings on chemosensitization of different cancer types in both pre-clinical and clinical settings. Contents: Introduction and Basic Concepts of Cancer (Devivasha Bordoloi, Bethsebie Lalduhsaki Sailo, Nafiseh Manteghi, Ganesan Padmavathi and Ajaikumar B Kunnumakkara ) Cancer Cell Chemoresistance: A Prime Obstacle in Cancer Therapy (Javadi Monisha, Aviral Jaiswal, Kishore Banik, Harsha Choudhary, Anuj Kumar Singh, Devivasha Bordoloi and Ajaikumar B Kunnumakkara) Bladder Cancer: Chemoresistance and Chemosensitization (Nand Kishor Roy, Anand Sharma, Anuj Kumar Singh, Devivasha Bordoloi, Bethsebie Lalduhsaki Sailo, Javadi Monisha and Ajaikumar B Kunnumakkara) Mechanism of Chemoresistance in Bone Cancer and Different Chemosensitization Approaches (Ganesan Padmavathi, Devivasha Bordoloi, Kishore Banik, Javadi Monisha, Anuj Kumar Singh and Ajaikumar B Kunnumakkara) Chemoresistance in Brain Cancer and Different Chemosensitization Approaches (Amrita Devi Khwairakpam, Javadi Monisha, Kishore Banik, Harsha Choudhary, Anand Sharma, Devivasha Bordoloi and Ajaikumar B Kunnumakkara) Phytochemicals as Chemosensitizers in Breast Cancer (Madhumita Roy, Ruma Sarkar, Apurba Mukherjee, Sutapa Mukherjee and Jaydip Biswas) Potential of Different Chemosensitizers to Overcome Chemoresistance in Cervical Cancer (Kishore Banik, Bethsebie Lalduhsaki Sailo, Krishan Kumar Thakur, Aviral Jaiswal, Javadi Monisha, Devivasha Bordoloi and Ajaikumar B. Kunnumakkara) Colon Cancer Chemoresistance and Chemosensitization (Muthu K Shanmugam, Arunasalam Dharmarajan, Frank Arfuso and Gautam Sethi) Cancer Cell Chemoresistance and Chemosensitization in Endometrial Cancer (Anuj Kumar Singh, Javadi Monisha, Kishore Banik, Harsha Choudhary, Amrita Devi Khwairakpam, Devivasha Bordoloi and Ajaikumar B Kunnumakkara) Different Approaches to Overcome Chemoresistance in Esophageal Cancer (Devivasha Bordoloi, Kishore Banik, Amrita Devi Khwairakpam, Anand Sharma, Javadi Monisha, Bethsebie Lalduhsaki Sailo and Ajaikumar B Kunnumakkara) Different Chemosensitization Approaches in Gastric Cancer (Harsha Choudhary, Devivasha Bordoloi, Jai Prakash, Nafiseh Manteghi, Ganesan Padmavathi, Javadi Monisha and Ajaikumar B Kunnumakkara) Chemoresistance and Chemosensitization in Hematological Malignancies (Ota Fuchs) Different Methods to Inhibit Chemoresistance in Hepatocellular Carcinoma (Anuj Kumar Singh, Nand Kishor Roy, Anand Anip, Kishore Banik, Javadi Monisha, Devivasha Bordoloi



Nutraceuticals In Veterinary Medicine


Nutraceuticals In Veterinary Medicine
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Author : Ramesh C. Gupta
language : en
Publisher: Springer
Release Date : 2019-05-21

Nutraceuticals In Veterinary Medicine written by Ramesh C. Gupta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-21 with Science categories.


This unique work compiles the latest knowledge around veterinary nutraceuticals, commonly referred to as dietary supplements, from ingredients to final products in a single source. More than sixty chapters organized in seven sections collate all related aspects of nutraceutical research in animal health and disease, among them many novel topics: common nutraceutical ingredients (Section-I), prebiotics, probiotics, synbiotics, enzymes and antibacterial alternatives (Section-II), applications of nutraceuticals in prevention and treatment of various diseases such as arthritis, periodontitis, diabetes, cognitive dysfunctions, mastitis, wounds, immune disorders, and cancer (Section-III), utilization of nutraceuticals in specific animal species (Section-IV), safety and toxicity evaluation of nutraceuticals and functional foods (Section-V), recent trends in nutraceutical research and product development (Section-VI), as well as regulatory aspects for nutraceuticals (Section-VII). The future of nutraceuticals and functional foods in veterinary medicine seems bright, as novel nutraceuticals will emerge and new uses of old agents will be discovered. International contributors to this book cover a variety of specialties in veterinary medicine, pharmacology, pharmacognosy, toxicology, chemistry, medicinal chemistry, biochemistry, physiology, nutrition, drug development, regulatory frameworks, and the nutraceutical industry. This is a highly informative and carefully presented book, providing scientific insight for academia, veterinarians, governmental and regulatory agencies with an interest in animal nutrition, complementary veterinary medicine, nutraceutical product development and research.



Antiangiogenic Drugs As Chemosensitizers In Cancer Therapy


Antiangiogenic Drugs As Chemosensitizers In Cancer Therapy
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-01-14

Antiangiogenic Drugs As Chemosensitizers In Cancer Therapy written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-14 with Science categories.


Anti-angiogenic Drugs as Chemosensitizers in Cancer Therapy, Volume 19 focuses on the use of anti-angiogenic drugs as sensitizers of tumor cells to the inhibitory activity of antitumor agents. Conventional and novel anti-neoplastic agents (cytotoxic molecules, hormones/antihormones, immunotherapies) are taken into consideration, along with advances made in combination therapies. The book encompasses examples of studies on the use of antiangiogenic compounds—molecules that inhibit the growth of vessels inside a tumor—together with antineoplastic drugs in order to sensitize the resistant tumor to their cytotoxic effects, thus reducing adverse side reactions and resistance and improving the therapeutic response of cancer patients. In addition, the book discusses clinical applications in various types of cancer, such as colorectal, lung, breast, renal, genitourinary, skin and brain and circulating tumors. It is a valuable resource for cancer researchers, clinicians and members of the biomedical field who wants to be up-to-date on the most recent and promising developments in the field. Provides the most updated reviews on anti-angiogenic drugs as chemosensitizers by leaders in the field Encompasses summarized tables and schematic diagrams in each chapter to give a clear overview on recent findings in a didactic manner Brings not only relevant information of current research but also new ideas and suggestions for further investigations to help advance the field



Ph Interfering Agents As Chemosensitizers In Cancer Therapy


Ph Interfering Agents As Chemosensitizers In Cancer Therapy
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Author : Claudiu T. Supuran
language : en
Publisher: Academic Press
Release Date : 2020-09-03

Ph Interfering Agents As Chemosensitizers In Cancer Therapy written by Claudiu T. Supuran and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-03 with Science categories.


pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. The continuous discovery and assessment of the role played by old/new synthetic drugs, natural compounds and technological applications has led to the urgent need of classification in terms of biological activity, mechanism of action, clinical outcomes, cancer cell lines sensible to the treatment, and potentialities to better orient research in this field. Moreover, all the aspects relevant for medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modeling studies) are strictly considered. Presents a broad view of the topic according to a medicinal chemistry-based approach beyond syntheses and biological assays, focusing on SAR studies, chemoinformatic, drug targeting and molecular modeling Explains the mechanism of action of the chemosensitizers by means of schemes and figures to facilitate comprehension Discusses novel targets to explore new possibilities that enhance research in the field