Role Of Oxidative Stress In Oral Diseases
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Role Of Oxidative Stress In Oral Diseases
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Author : Alexandrina L. Dumitrescu
language : en
Publisher: Frontiers Media SA
Release Date : 2019-12-10
Role Of Oxidative Stress In Oral Diseases written by Alexandrina L. Dumitrescu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-10 with categories.
Role Of Oxidative Stress In Pathophysiology Of Diseases
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Author : Pawan K. Maurya
language : en
Publisher: Springer Nature
Release Date : 2020-06-15
Role Of Oxidative Stress In Pathophysiology Of Diseases written by Pawan K. Maurya and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-15 with Science categories.
This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases. The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders. Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress. Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress.
Oxidative Stress And Biomaterials
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Author : Thomas Dziubla
language : en
Publisher: Academic Press
Release Date : 2016-05-31
Oxidative Stress And Biomaterials written by Thomas Dziubla and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-31 with Technology & Engineering categories.
Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of “meso-compatibility, a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction. Explores the challenges of designing and using biomaterials in order to minimize oxidative stress, reducing patterns of chronic inflammation and cell death Brings together the two fields of biomaterials and the biology of oxidative stress Provides approaches for the design of biomaterials with improved biocompatibility
Biomaterials And Designer Functional Applications In Oral Cavity
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Author : V. Tamara Perchyonok
language : en
Publisher: Nova Science Publishers
Release Date : 2016
Biomaterials And Designer Functional Applications In Oral Cavity written by V. Tamara Perchyonok and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Medical categories.
Dental biomaterials and natural products represent two growing research fields, revealing that plant-derived compounds may play a role not only as nutraceuticals in affecting oral health but also in improving physicochemical properties of biomaterials used in dentistry. Recently, the role of free radicals in healthcare has attracted tremendous interest in the field of medicine, dentistry and molecular biology. Free radicals can be either harmful or helpful to the human body. When there is an imbalance between input and output of free radicals, a condition called "oxidative stress" develops. To counteract oxidative stress, the body has protective antioxidant mechanisms, which aid in lowering the incidence of various human morbidities and mortalities. The implication of oxidative stress in the etiology of many chronic and degenerative diseases suggests that antioxidant therapy represents a promising avenue for treatment. Thus, various forms of antioxidants have been introduced as an approach to fight dental diseases and improve general gingival health. The implication of oxidative stress in the etiology of chronic and degenerative diseases as well as the body's protective antioxidant mechanisms and the role dietary antioxidants play, suggests that antioxidant therapy could act as a beneficial treatment. The aim of this book is to present all available data concerning and linking free radicals, antioxidants and bio-active scaffolds in the utilization of vitamins, proteins and extracts rich in bio-active phytochemicals as an avenue for creating innovative dental biomaterials. These materials are capable of promoting genuine tissue/cell interface integration and gaining insight into molecular origin of the mechanism to combat oral diseases in vitro and eventually in vivo.
Oxidative Stress And Antioxidant Protection
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Author : Donald Armstrong
language : en
Publisher: John Wiley & Sons
Release Date : 2016-04-11
Oxidative Stress And Antioxidant Protection written by Donald Armstrong and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-11 with Science categories.
Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.
Oxidative Stress And Chronic Degenerative Diseases
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Author : Jose Antonio Morales-Gonzalez
language : en
Publisher: BoD – Books on Demand
Release Date : 2013-05-22
Oxidative Stress And Chronic Degenerative Diseases written by Jose Antonio Morales-Gonzalez and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-22 with Science categories.
This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.
Insights Into Various Aspects Of Oral Health
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Author : Jane Manakil
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-09-20
Insights Into Various Aspects Of Oral Health written by Jane Manakil and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-20 with Medical categories.
Chronic inflammation such as seen in periodontitis and its bidirectional influence on the systemic health has been of increased interest for a decade. In this text book, we have explored the biological and genetic pathways by which periodontal diseases may influence these disease processes and vice versa. Occlusal rehabilitation using the MEAW technique for the effective treatment of class II deep bite malocclusion and the timely management of cleft lip and palate to benefit the holistic welfare of the patient are presented here. The book addresses the development of bioinspired functionally graded dental restorative materials and also a simulation method that can improve clinical durability and enhance the functional capability of the dentition and indirect prostheses. In conclusion, various pathways for the promotion of oral health with evidence-based concepts are considered.
Studies On Periodontal Disease
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Author : Daisuke Ekuni
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-09
Studies On Periodontal Disease written by Daisuke Ekuni and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-09 with Science categories.
The chapters of Studies on Periodontal Disease comprise four parts. Part 1 provides basic sciences from the general to the particular. The findings of cell culture and animal models supply the mechanism between periodontal disease and oxidative stress. In part 2, human clinical studies are mainly addressed. The effects of periodontal therapy on circulating oxidative stress are also discussed. The relationships between periodontal disease and systemic diseases are examined in part 3. The involvement of oxidative stress and inflammation are discussed through in vivo and in vitro study results. Part 4 discusses future strategies, including the effects of antioxidants and nutrition on periodontal disease. This thorough examination of the relationship between oxidative stress and periodontal disease is essential reading for researchers in oxidative stress and periodontal clinicians, alike.
Glutathione System And Oxidative Stress In Health And Disease
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-08-26
Glutathione System And Oxidative Stress In Health And Disease written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-26 with Science categories.
The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.
Handbook Of Oxidative Stress In Cancer Therapeutic Aspects
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Author : Sajal Chakraborti
language : en
Publisher: Springer Nature
Release Date : 2022-09-28
Handbook Of Oxidative Stress In Cancer Therapeutic Aspects written by Sajal Chakraborti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-28 with Medical categories.
This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy.