Sample Size Tables For Clinical Studies

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Sample Size Tables For Clinical Studies

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Author : David Machin
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-26

Sample Size Tables For Clinical Studies written by David Machin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-26 with Medical categories.

This book provides statisticians and researchers with the statistical tools - equations, formulae and numerical tables - to design and plan clinical studies and carry out accurate, reliable and reproducible analysis of the data so obtained. There is no way around this as incorrect procedure in clinical studies means that the researcher's paper will not be accepted by a peer-reviewed journal. Planning and analysing clinical studies is a very complicated business and this book provides indispensible factual information. Please go to http://booksupport.wiley.com and enter 9781405146500 to easily download the supporting materials.

Sample Size Tables For Clinical Studies Second Edition

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Author : David Machin
language : en
Publisher: Wiley-Blackwell
Release Date : 1997-12-12

Sample Size Tables For Clinical Studies Second Edition written by David Machin and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-12-12 with Medical categories.

This book provides statisticians and researchers with the statistical tools (equations, formulae and numerical tables) needed to design clinical studies and carry out accurate, reliable, and reproducible analysis of the data obtained. For this second edition, six entirely new topics have been added and many chapters have been considerably expanded. This edition also comes packaged with a free computer disk. The disk contains a software application designed to be used in conjunction with the text, which greatly simplifies the process of looking up tabulated, sample-size values.

Sample Sizes For Clinical Trials

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Author : Steven A. Julious
language : en
Publisher: CRC Press
Release Date : 2009-08-26

Sample Sizes For Clinical Trials written by Steven A. Julious and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-26 with Mathematics categories.

Drawing on various real-world applications, Sample Sizes for Clinical Trials takes readers through the process of calculating sample sizes for many types of clinical trials. It provides descriptions of the calculations with a practical emphasis.Focusing on normal, binary, ordinal, and survival data, the book explores a range of trials, including su

Sample Size Methodology

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Author : M. M. Desu
language : en
Publisher:
Release Date : 1990

Sample Size Methodology written by M. M. Desu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Mathematics categories.

One of the most important problems in designing an experiment or a survey is sample size determination and this book presents the currently available methodology. It includes both random sampling from standard probability distributions and from finite populations. Also discussed is sample size determination for estimating parameters in a Bayesian setting by considering the posterior distribution of the parameter and specifying the necessary requirements. The determination of the sample size is considered for ranking and selection problems as well as for the design of clinical trials. Appropriate techniques for attacking the general question of sample size determination in problems of estimation, tests of hypotheses, selection, and clinical trial design are all presented, and will help the reader in formulating an appropriate problem of sample size and in obtaining the solution. The book can be used as a text in a senior-level or a graduate course on sample size methodology. Annotated list of tables in appendixSupplemental problems at the end of book

Statistical Tables For The Design Of Clinical Trials

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Author : David Machin
language : en
Publisher: Wiley-Blackwell
Release Date : 1987-01-01

Statistical Tables For The Design Of Clinical Trials written by David Machin and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-01-01 with Clinical trials categories.

Introduction To Educational Research

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Author : W. Newton Suter
language : en
Publisher: SAGE
Release Date : 2012

Introduction To Educational Research written by W. Newton Suter and has been published by SAGE this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Education categories.

W. Newton Suter argues that what is important in a changing education landscape is the ability to think clearly about research methods, reason through complex problems and evaluate published research. He explains how to evaluate data and establish its relevance.

An Introduction To Medical Statistics

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Author : Martin Bland
language : en
Publisher: OUP Oxford
Release Date : 2015-07-23

An Introduction To Medical Statistics written by Martin Bland and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-23 with Medical categories.

Now in its Fourth Edition, An Introduction to Medical Statistics continues to be a 'must-have' textbook for anyone who needs a clear logical guide to the subject. Written in an easy-to-understand style and packed with real life examples, the text clearly explains the statistical principles used in the medical literature. Taking readers through the common statistical methods seen in published research and guidelines, the text focuses on how to interpret and analyse statistics for clinical practice. Using extracts from real studies, the author illustrates how data can be employed correctly and incorrectly in medical research helping readers to evaluate the statistics they encounter and appropriately implement findings in clinical practice. End of chapter exercises, case studies and multiple choice questions help readers to apply their learning and develop their own interpretative skills. This thoroughly revised edition includes new chapters on meta-analysis, missing data, and survival analysis.

Sample Size Determination And Power

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Author : Thomas P. Ryan
language : en
Publisher: John Wiley & Sons
Release Date : 2013-05-28

Sample Size Determination And Power written by Thomas P. Ryan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-28 with Medical categories.

A comprehensive approach to sample size determination and power with applications for a variety of fields Sample Size Determination and Power features a modern introduction to the applicability of sample size determination and provides a variety of discussions on broad topics including epidemiology, microarrays, survival analysis and reliability, design of experiments, regression, and confidence intervals. The book distinctively merges applications from numerous fields such as statistics, biostatistics, the health sciences, and engineering in order to provide a complete introduction to the general statistical use of sample size determination. Advanced topics including multivariate analysis, clinical trials, and quality improvement are addressed, and in addition, the book provides considerable guidance on available software for sample size determination. Written by a well-known author who has extensively class-tested the material, Sample Size Determination and Power: Highlights the applicability of sample size determination and provides extensive literature coverage Presents a modern, general approach to relevant software to guide sample size determination including CATD (computer-aided trial design) Addresses the use of sample size determination in grant proposals and provides up-to-date references for grant investigators An appealing reference book for scientific researchers in a variety of fields, such as statistics, biostatistics, the health sciences, mathematics, ecology, and geology, who use sampling and estimation methods in their work, Sample Size Determination and Power is also an ideal supplementary text for upper-level undergraduate and graduate-level courses in statistical sampling.

Sharing Clinical Trial Data

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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2015-04-20

Sharing Clinical Trial Data written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-20 with Medical categories.

Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.

Field Trials Of Health Interventions

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Author : Peter G. Smith
language : en
Publisher:
Release Date : 2015

Field Trials Of Health Interventions written by Peter G. Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Health & Fitness categories.

This is an open access title available under the terms of a CC BY-NC 4.0 International licence. It is free to read at Oxford Scholarship Online and offered as a free PDF download from OUP and selected open access locations. Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in field trials'. These may be complex and expensive undertakings, requiring the follow-up of hundreds, or thousands, of individuals, often for long periods. Descriptions of the detailed procedures and methods used in the trials that have been conducted have rarely been published. A consequence of this, individuals planning such trials have few guidelines available and little access to knowledge accumulated previously, other than their own. In this manual, practical issues in trial design and conduct are discussed fully and in sufficient detail, that Field Trials of Health Interventions may be used as a toolbox' by field investigators. It has been compiled by an international group of over 30 authors with direct experience in the design, conduct, and analysis of field trials in low and middle income countries and is based on their accumulated knowledge and experience. Available as an open access book via Oxford Medicine Online, this new edition is a comprehensive revision, incorporating the new developments that have taken place in recent years with respect to trials, including seven new chapters on subjects ranging from trial governance, and preliminary studies to pilot testing.