Sarcoidosis Diagnosis Research And Therapy Of A Granulomatous Disease


Sarcoidosis Diagnosis Research And Therapy Of A Granulomatous Disease
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Sarcoidosis Diagnosis Research And Therapy Of A Granulomatous Disease


Sarcoidosis Diagnosis Research And Therapy Of A Granulomatous Disease
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Author : Jelena Stojšić
language : en
Publisher: BoD – Books on Demand
Release Date : 2024-02-14

Sarcoidosis Diagnosis Research And Therapy Of A Granulomatous Disease written by Jelena Stojšić and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-14 with Medical categories.


Sarcoidosis is a generalized, systemic, and specific granulomatous disease involving many organs and systems. Diagnosis of sarcoidosis is challenging, especially when mediastinal lymph nodes and lungs are not affected. The symptoms of sarcoidosis depend on its location. Differential diagnosis of sarcoidosis among the other specific granulomatous diseases is difficult, particularly with tuberculosis on biopsy. The etiology of sarcoidosis is still unknown, but this book offers insights and explanations. It also presents guidelines for treatment.



Sarcoidosis


Sarcoidosis
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Author : Michael R. Connor
language : en
Publisher: Nova Science Publishers
Release Date : 2012

Sarcoidosis written by Michael R. Connor and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Sarcoidosis categories.


Sarcoidosis is a systemic inflammatory granulomatous disease of unknown origin, with a wide variety of imaging features. The organs most commonly involved are the lungs, eyes, and skin. The characteristic histologic lesion, a non-caseating granuloma, has been described as affecting all organ systems. In this book, the authors present topical research in the study of the diagnosis, epidemiology and treatment options for sarcoidosis. Topics include recent advances in the immunogenetics of sarcoidosis; nodular sarcoidosis; pulmonary hypertension associated with sarcoidosis; nuclear medicine imaging in the diagnosis of cardiac sarcoidosis and an experimental model of sarcoidosis using Kveim tissue.



Diffuse Lung Disease


Diffuse Lung Disease
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Author : Robert P. Baughman
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-04

Diffuse Lung Disease written by Robert P. Baughman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-04 with Medical categories.


Interstitial lung diseases comprise a significant part of any respiratory medicine practice. This timely second edition of Diffuse Lung Disease is a practical clinically-oriented resource, covering all the major advances in diagnostic techniques and therapies. Authored by world authorities in the field, this book provides clear and specific recommendations for the management of all forms of interstitial lung diseases. This book is divided into two sections. The first section addresses the general aspects of diagnosis and management, including clinical approach, radiographic approach, physiological changes, and classification. The second section details each individual form of interstitial lung disease. Organized in an easy to follow format, each disease specific chapter includes tables outlining diagnostic approach, differential diagnosis, disease monitoring, and treatment. Illustrative cases, replete with high quality HRCT images, bring an added dimension to this outstanding book.



The Granulomatous Disorders


The Granulomatous Disorders
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Author : D. Geraint James
language : en
Publisher: Cambridge University Press
Release Date : 1999-09-09

The Granulomatous Disorders written by D. Geraint James and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-09 with Medical categories.


This authoritative account of the granulomatous disorders provides a comprehensive overview of this complex group of diseases. Collectively, these disorders can present a bewildering array of symptoms, affecting all the body systems. This volume takes full account of recent advances in our knowledge of the molecular biology and immunology of these disorders, and casts fresh light on their diagnosis and treatment. This timely publication is organised to include chapters focused on causative agents and those addressing affected body systems. Highly illustrated throughout, including numerous colour plates, it encompasses and integrates the very latest science, pathology and practical clinical advice. Compiled by international authorities with chapters which combine the expertise of both a pathologist and clinician, it is sure to become an essential source of reference for a very wide readership including infectious disease specialists, immunologists, pathologists, radiologists, ophthalmologists and general physicians.



Sarcoidosis And Granulomatosis


Sarcoidosis And Granulomatosis
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Author : Mohammad Hosein Motamedi
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-07-29

Sarcoidosis And Granulomatosis written by Mohammad Hosein Motamedi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-29 with Medical categories.


Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis.



Clinical Manifestations Pathophysiology Diagnostic Methods Imaging And Intervention In Sarcoidosis


Clinical Manifestations Pathophysiology Diagnostic Methods Imaging And Intervention In Sarcoidosis
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Author : Ali Nawaz Khan
language : en
Publisher:
Release Date : 2016-12-01

Clinical Manifestations Pathophysiology Diagnostic Methods Imaging And Intervention In Sarcoidosis written by Ali Nawaz Khan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-01 with categories.


Sarcoidosis is a multisystem granulomatous disease of unknown etiology that is characterised by noncaseous epithelioid cell granulomas, which may affect almost any organ in the body. Intrathoracic involvement is common and accounts for most of the morbidity and mortality associated with this disease. The diagnosis is based on the total exclusion of other granulomatous disorders. The organs that are commonly involved are the lymph nodes, lungs, liver, spleen, skin, and eyes; these organs can be involved individually or in combination. The correlation of the clinical, radiological features along with the pathologic finding of non-caseating epithelioid cell granulomas is vital to establish the diagnosis. There is no single precise cause attributed to the causation of this disease. Genetic factors are suspected, due to the observation that racial groups such as African Americans, West Indians and Asians have a higher prevalence of sarcoidosis. Familial sarcoidosis is well-known, which may be attributed to genetic factors or the sharing of a similar environment. Environmental factors may also play a role by involving the uptake and processing of unknown antigens by the respiratory system. Occasional patients with sarcoidosis have an association with primary biliary cirrhosis, where the granulomas in both diseases look similar. Patients receiving treatment with anti-retroviral therapy or interferon alpha might have pulmonary granulomas as in HIV-infected patients and leukemia patients retrospectively. Sarcoidosis is more prevalent and is a more severe disease in blacks in the United States of America. Two-thirds of patients with sarcoidosis resolve spontaneously without specific treatment. Therapeutic measures, when required, rely on immune suppression. As the symptoms are varied in sarcoidosis, the differential diagnosis includes most non-specific systemic disorders. A chest radiograph (CXR) is usually the first diagnostic imaging study in patients with respiratory symptoms. A CXR is a non-invasive modality, widely available, easy to interpret and when correlated with the clinical findings, may be the only imaging required to diagnose pulmonary sarcoidosis. A CXR is also the most commonly used imaging technique for follow-up in patients with established diagnosis, and is reproducible and cost efficient. Conventional chest radiography, however, has its limitations. While it may be normal in 5-10% of patients with established sarcoidosis, in 25-30% of patients, the radiologic changes are nonspecific or atypical reducing the plain film sensitivity. In such cases, High-Resolution CT (HRCT) is useful in clarifying the diagnosis providing crucial information on the extent of the disease. Furthermore, HRCT, unlike a plain radiograph, can readily differentiate active inflammation from irreversible fibrosis.



Sarcoidosis


Sarcoidosis
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Author : Donald N Mitchell
language : en
Publisher: CRC Press
Release Date : 2012-02-24

Sarcoidosis written by Donald N Mitchell and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-24 with Medical categories.


Highly Commended, BMA Medical Book Awards 2013 Sarcoidosis represents a major challenge for physicians—not just in respiratory medicine, but across a range of specialties. This book, with a multidisciplinary authorship of the highest standard, presents the most up-to-date thinking on all aspects of the condition, from epidemiology to clinical manifestations and treatment options. Full coverage is given to both respiratory and non-respiratory aspects. The basic science that underlies the disease and its progression is evaluated in detail, and placed into its correct clinical context. Possible future advances are covered in a concluding section. The editors—all leading figures in the field with international reputations—have compiled the definitive work on the subject in a single volume. The book is fully comprehensive and evidence based and will be an essential addition to the bookshelves of all whose practice involves the care and treatment of patients with sarcoidosis.



Sarcoidosis


Sarcoidosis
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Author : Robert Phillip Baughman
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-11-30

Sarcoidosis written by Robert Phillip Baughman and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-30 with Medical categories.


Get a quick, expert overview of the etiology, diagnosis, and management of pulmonary and extra pulmonary sarcoidosis with this concise, practical resource. Drs. Robert B. Baughman and Dominique Valeyre fully cover the recent advances in various aspects of this disease, including new genetic studies and new diagnostic techniques. It’s an ideal resource for pulmonologists and respiratory medicine specialists, as well as primary care physicians and pulmonary/respiratory care nurses. Provides a comprehensive discussion of the various facets of sarcoidosis, including common manifestations of the lung, skin, and eyes, as well as other important aspects such as cardiac and neurologic disease. Covers newer diagnostic techniques for the lungs and elsewhere in the body, each discussed in detail and compared to older diagnostic techniques. Discusses treatment options including anti-inflammatory drugs, and management of other aspects of the disease, such as pulmonary hypertension, fatigue, and small fiber neuropathy. Consolidates today’s available information and experience in this important area into one convenient resource.



Sarcoidosis And Other Granulomatous Diseases Of The Lung


Sarcoidosis And Other Granulomatous Diseases Of The Lung
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Author : Barry L. Fanburg
language : en
Publisher:
Release Date : 1983

Sarcoidosis And Other Granulomatous Diseases Of The Lung written by Barry L. Fanburg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.




Clinical Focus Series Lesions Of Sarcoidosis


Clinical Focus Series Lesions Of Sarcoidosis
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Author : Om P Sharma
language : en
Publisher: JP Medical Ltd
Release Date : 2014-02-28

Clinical Focus Series Lesions Of Sarcoidosis written by Om P Sharma and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-28 with Medical categories.


Sarcoidosis is a rare condition that causes small patches of red and swollen tissue, called granulomas, to develop in the organs of the body. It most often affects the lungs and skin. Typical symptoms include tender, red bumps on the skin, shortness of breath and a persistent cough. There is no cure for sarcoidosis, but the condition often improves without treatment within a few months or years. Sarcoidosis is estimated to affect about 1 in every 10,000 people in the UK (NHS Choices). Part of the Clinical Focus Series, this book provides trainees with an overview of this complex condition. Beginning with an introduction and guidance on recognising pulmonary granulomas, the following chapters provide in depth coverage of numerous common lesions, describing their history, clinical features, differential diagnosis and treatment. Presented in an easy to read format, this useful reference includes clinical photographs, CT scans and X-rays, histological pictures and tables to enhance learning. Key points Provides practical overview of lesions of sarcoidosis Covers numerous common lesions, their history, clinical features, diagnosis and treatment Presented in easy to read format, with problem solving approach Includes clinical photographs, CT Scans, X-rays, histological pictures and tables