Scaleup Of Chemical Processes

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Scale Up Methodology For Chemical Processes

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Author : Jean-Paul Euzen
language : en
Publisher: Editions TECHNIP
Release Date : 1993

Scale Up Methodology For Chemical Processes written by Jean-Paul Euzen and has been published by Editions TECHNIP this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Science categories.

Having gained considerable experience in process development at the Institut FranCais du PEtrole, the authors present a design framework, a review of the available means of investigation, and several examples illustrating their methodology of industrial process scale up. The salient feature of the book is the fact that it addresses a subject which is vital in view of its economic repercussions, yet relatively unknown in technical and scientific circles, due to the confidentiality surrounding it.Contents: 1. Main guidelines of the methodology. 2. Various types of model. 3. Pilot plants and mock-ups. 4. Experimental techniques. 5. Applications to industrial process development. 6. Conclusions. References. Index.

Scaleup Of Chemical Processes

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Author : Attilio Bisio
language : en
Publisher: Wiley-Interscience
Release Date : 1985

Scaleup Of Chemical Processes written by Attilio Bisio and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Science categories.

The focus of this book is on the technical factors that are critical to th e design and startup of a commercial manufacturing facility.

Scale Up Processes

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Author : Jamal Chaouki
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2021-09-20

Scale Up Processes written by Jamal Chaouki and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-20 with Technology & Engineering categories.

Common scale-up methods are conventional where the blind piloting is essential. This imposes huge investment and leads to failures mostly in solid processing. However, the limitations of resources, current shortcomings, short time-to-market demand are forced companies to minimize piloting. With these situations in mind, current digitalization outlook and computational facilities, we proposed and developed a novel iterative scale up method with case studies which highly expedites the process innovation through the following key sequences:

Dimensional Analysis And Scale Up In Chemical Engineering

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Author : Marko Zlokarnik
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Dimensional Analysis And Scale Up In Chemical Engineering written by Marko Zlokarnik and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Contemporary Chemical Process Engineers face complex design and research problems. Temperature-dependent physical properties and non-Newtonian flow behavior of substances in a process cannot be predicted by numerical mathematics. Scaling-up equipment for processing can often only be done with partial similarity methods. Standard textbooks often neglect topics like dimensional analysis, theory of similarity and scale-up. This book fills this gap! It is aimed both at university students and the process engineer. It presents dimensional analysis very comprehensively with illustrative examples of mechanical, thermal and chemical processes.

Industrial Process Scale Up

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Author : Jan Harmsen
language : en
Publisher: Elsevier
Release Date : 2013-04-25

Industrial Process Scale Up written by Jan Harmsen and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-25 with Technology & Engineering categories.

This book will help industrial process innovators in research, development and commercial start-up to assess the risks of commercial-scale implementation and provide them with practical guidelines and methods to reduce the risks to acceptable levels. The book can also be used in co-operation with industrial R&D people and academic researchers to shape open innovation programs and in education as a reference book for process innovation courses. - Offers easily accessible, step-by-step, and concise guidelines for industrial process scale-up - Explains each stage of the innovation funnel: research, development, demonstration, commercial implementation for any process type and branch - Based on industrial experiences and practices, which reduces the risks of commercial scale implementation of new processes to acceptable levels and reduces cost and time of process innovation - Very clear, attractive layout, using text boxes that contain clarifying notes and additional information on specific topics, which makes it a quick reference of main subjects and additional information

Chemical Engineering In The Pharmaceutical Industry

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Author : Mary T. am Ende
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-08

Chemical Engineering In The Pharmaceutical Industry written by Mary T. am Ende and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-08 with Technology & Engineering categories.

A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Chemical Reactor Design

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Author : E. B. Nauman
language : en
Publisher:
Release Date : 1987

Chemical Reactor Design written by E. B. Nauman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Chemical reactors categories.

Pharmaceutical Process Chemistry For Synthesis

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Author : Peter J. Harrington
language : en
Publisher: John Wiley & Sons
Release Date : 2011-02-23

Pharmaceutical Process Chemistry For Synthesis written by Peter J. Harrington and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-23 with Science categories.

There is a need to explain that generic versions of a drug may not be manufactured by the same process as brand-name drugs and that the different processes may have dramatically different environmental impacts. Two global forces are at odds today—the push for "greener" processes and the push for lower drug prices. This book brings this conflict into sharp focus by discussing in detail the published process chemistry for top-selling small molecule drugs. Providing insights about process route selection, choice of reagents, and reaction conditions, Pharmaceutical Process Chemistry for Synthesis guides process chemists in identifying best processes for manufacturing these blockbuster drugs as they lose patent protection. Further, it highlights the strategies and methodology that might be useful for expediting the process research and development of the blockbusters of the future. Written from a refreshingly objective perspective, this book is essential for process chemists who need to devise practical syntheses for increasingly complex drugs in a constantly decreasing time frame.

Chemical Process Simplification

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Author : Girish K. Malhotra
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-21

Chemical Process Simplification written by Girish K. Malhotra and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-21 with Science categories.

While emphasizing conservation and sustainable strategies, this book provides steps to improve the manufacturing technologies used in creating products. By simplifying the chemistry, process development, manufacturing practices and processes, the book provides a structured approach to producing quality products with little waste, making the process not only efficient but environmentally friendly. Illustrated with case studies, this is an essential resource for chemical engineers, chemists, plant engineers, and operating personnel in any chemical related businesses.

Scale Up And Chemical Process For Microbial Production Of Plant Derived Bioactive Compounds

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Author : Yongjun Wei
language : en
Publisher: Elsevier
Release Date : 2024-03-20

Scale Up And Chemical Process For Microbial Production Of Plant Derived Bioactive Compounds written by Yongjun Wei and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-20 with Science categories.

Many plant-derived bioactive compounds are the foundation for drugs or effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limited th - Introduces the scale-up and chemical process development for microbial production of plant-derived bioactive compounds - Covers the useful and effective sustainable and commercial production of plant-derived bioactive compounds - Provides a guide for commercial production of plant-derived bioactive compounds and their uses for human welfare