Schizophrenia Human And Animal Studies
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Schizophrenia Human And Animal Studies
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Author : Thomas W. Weickert
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-21
Schizophrenia Human And Animal Studies written by Thomas W. Weickert and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-21 with Science categories.
This volume contains research articles and reviews describing behavioral, cognitive, computational, genetic, and pharmacological studies of schizophrenia. Articles will include reports on the latest research on neural substrates of positive, negative, and cognitive symptoms in schizophrenia; computational theory; behavioral neurogenetic, and neuropsychological studies of schizophrenia. We also welcome research articles reporting effects of medications, including antipsychotics, on schizophrenia symptoms and behavior.
Animal Models For The Study Of Human Disease
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Author : David Feifel
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-29
Animal Models For The Study Of Human Disease written by David Feifel and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-29 with Medical categories.
Modeling schizophrenia in animals represents a formidable challenge because the most characteristic symptoms of this disorder, auditory hallucinations and delusional beliefs, cannot be directly modeled in animals. Furthermore, limited current understanding of the etiology and pathophysiology underlying the clinical features of this disorder greatly hinders the ability to develop valid models based on those aspects. To circumvent these issues, investigators have attempted to recreate the leading candidate biochemical, neuroanatomical, and genetic abnormalities for this disorder in animals using pharmacological, developmental, neurotoxic, genetic engineering, and other methods. The validity of these animal preparations as animal models for schizophrenia is generally based upon the extent to which they induce measurable behavioral changes that are homologous or analogous to the core clinical features or the information-processing endophenotypes (presymptom phenotypes) that are seen in schizophrenia. The utility of any animal model to serve as a screen for novel treatments is considered related to the extent to which the schizophrenia-relevant behaviors it exhibits can be ameliorated by drugs with known efficacy in schizophrenia but not by drugs known to be therapeutic for brain disorders other than schizophrenia.
Animal Models For Psychiatry
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Author : J. D. Keehn
language : en
Publisher: Routledge
Release Date : 2018-02-19
Animal Models For Psychiatry written by J. D. Keehn and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-19 with Psychology categories.
Originally published in 1986, in this work Professor Keehn assesses the contributions of experimental psychology and ethology to psychiatric theory and practice at the time. He discusses the status of animals in psychopathology, and describes a number of animal clinical pictures, covering both abnormal movements and convulsions, and spontaneous behavioural disorders. He also includes animal models of such psychiatric illnesses as neurosis, psychosis, drug addiction and disorders of childhood, and examines the nature of mental illness and the status of psychiatric diagnosis. The book includes an evaluation of the ethics of experimental research with animals and a summary of humane experimental procedures. Animal Models for Psychiatry will be of special interest to psychiatrists, clinical and physiological psychologists, behavioural pharmacologists, and to veterinarians.
First Episode Psychosis
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Author : Katherine J. Aitchison
language : en
Publisher: CRC Press
Release Date : 2022-03-26
First Episode Psychosis written by Katherine J. Aitchison and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-26 with Medical categories.
The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management. This is an authoritative text written by a team of highly respected authors for psychiatrists, neurologists, primary care practitioners and health care professional working in psychiatry. Drawing from their experience, the presentation and assessment of the first psychotic episode are discussed, details regarding antipsychotic drugs and their appropriate use are reviewed and psychosocial approaches are examined. The resulting book offers a concise and valuable guide to those wishing to review the latest proposals for the treatment of first-episode psychosis supported by up-to-date references, in a single publication.
Animal Models In Medicine And Biology
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Author : Eva Tvrdá
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-04-08
Animal Models In Medicine And Biology written by Eva Tvrdá and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-08 with Science categories.
Thanks to animal models, our knowledge of biology and medicine has increased enormously over the past decades, leading to significant breakthroughs that have had a direct impact on the prevention, management and treatment of a wide array of diseases.This book presents a comprehensive reference that reflects the latest scientific research being done in a variety of medical and biological fields utilizing animal models. Chapters on Drosophila, rat, pig, rabbit, and other animal models reflect frontier research in neurology, psychiatry, cardiology, musculoskeletal disorders, reproduction, chronic diseases, epidemiology, and pain and inflammation management. Animal Models in Medicine and Biology offers scientists, clinicians, researchers and students invaluable insights into a wide range of issues at the forefront of medical and biological progress.
Guidelines For The Care And Use Of Mammals In Neuroscience And Behavioral Research
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2003-08-22
Guidelines For The Care And Use Of Mammals In Neuroscience And Behavioral Research written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-22 with Science categories.
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Schizophrenia A Very Short Introduction
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Author : Chris Frith
language : en
Publisher: OUP Oxford
Release Date : 2003-05-22
Schizophrenia A Very Short Introduction written by Chris Frith and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-22 with Psychology categories.
Schizophrenia is the archetypal form of madness. Schizophrenia is a common disorder and has a devastating effect on sufferers and their families-patients typically hear voices in their heads and hold bizarre beliefs. The schizophrenic patient presented to the public in sensational press reports and lurid films bears little resemblance to reality of the illness. This book describes what schizophrenia is really like, how the illness progresses, and the treatments that have been applied. It also summarizes the most up-to-date knowledge available about the biological bases of this disorder. Finally it attempts to give some idea of what it is like to have schizophrenia and what this disorder tells us about the relationship between mind and brain. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Animal Experimentation Working Towards A Paradigm Change
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Author : Kathrin Herrmann
language : en
Publisher: BRILL
Release Date : 2019-04-30
Animal Experimentation Working Towards A Paradigm Change written by Kathrin Herrmann and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-30 with Philosophy categories.
Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.
Animal Models In Human Psychobiology
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Author : George Serban
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Animal Models In Human Psychobiology written by George Serban and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
In March, 1974, an International Symposium was held at the Harmonie Club in New York to discuss a highly pertinent problem in today's research: the "Rele vance of the Animal Psychopathological Model to the Human." This meeting was sponsored by the Kittay Foundation, which brought together an outstanding group of scientists involved in widely different fields of research. This volume, it is hoped, will convey the tone of lively and cordial exchange between inter nationally renowned investigators, including Dr. I. Eibl-Eibesfeldt from Germany, Dr. Robert A. Hinde from England, Dr. Edward F. Domino from Michigan, and Dr. Pierre Pichot from France, Chairman of the Steering Committee. In his welcoming address, Mr. Sol Kittay reminded us that man has achieved remarkable control over his environment but not over himself, and he suggested that we should reexamine our ancestral origins, and search in animal behavior for clues to the understanding of normal and abnormal behavior in man.
Science Medicine And Animals
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Author : Committee on the Use of Animals in Research (U.S.)
language : en
Publisher: National Academies Press
Release Date : 1991
Science Medicine And Animals written by Committee on the Use of Animals in Research (U.S.) and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
The necessity for animal use in biomedical research is a hotly debated topic in classrooms throughout the country. Frequently teachers and students do not have access to balanced,  factual material to foster an informed discussion on the topic. This colorful, 50-page booklet is designed to educate teenagers about the role of animal research in combating disease, past and present; the perspective of animal use within the whole spectrum of biomedical research; the regulations and oversight that govern animal research; and the continuing efforts to use animals more efficiently and humanely.