Sem Passar A Fronteira Classic Reprint
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Sem Passar A Fronteira Classic Reprint
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Author : ALBERTO. PIMENTEL
language : pt-BR
Publisher:
Release Date : 2022
Sem Passar A Fronteira Classic Reprint written by ALBERTO. PIMENTEL and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
The Landscape Of Lexicography
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Author : Alina Villalva
language : en
Publisher: Centro de Linguística da Universidade de Lisboa - Centro de Línguas, Literaturas e Culturas da universidade de Aveiro
Release Date : 2019-08-01
The Landscape Of Lexicography written by Alina Villalva and has been published by Centro de Linguística da Universidade de Lisboa - Centro de Línguas, Literaturas e Culturas da universidade de Aveiro this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-01 with Language Arts & Disciplines categories.
This book consists of a series of papers that look at three different aspects of the landscape as seen in dictionaries from across Europe. Multilingual diachronic case studies into lexicographical descriptions of flora, landscape features and colours concentrate on three supposedly simple words: daisies (Bellis perenis L.), hills and the colour red. The work is part of the ongoing LandLex initiative, originally developed as part of the COST ENeL - European Network for e-Lexicography - action. The group brings together researchers in lexicography and lexicology from across Europe and is dedicated to studying multilingual and diachronic issues in language. It aims to valorise the wealth of European language diversity as found in dictionaries by developing and testing new digital annotation tools and a historical morphological dictionary prototype. Funded by the Horizon 2020 Framework Programme of the European Union
The Island Of Knowledge
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Author : Marcelo Gleiser
language : en
Publisher: Hachette UK
Release Date : 2014-06-03
The Island Of Knowledge written by Marcelo Gleiser and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-03 with Science categories.
Do all questions have answers? How much can we know about the world? Is there such a thing as an ultimate truth? To be human is to want to know, but what we are able to observe is only a tiny portion of what's "out there." In The Island of Knowledge, physicist Marcelo Gleiser traces our search for answers to the most fundamental questions of existence. In so doing, he reaches a provocative conclusion: science, the main tool we use to find answers, is fundamentally limited. These limits to our knowledge arise both from our tools of exploration and from the nature of physical reality: the speed of light, the uncertainty principle, the impossibility of seeing beyond the cosmic horizon, the incompleteness theorem, and our own limitations as an intelligent species. Recognizing limits in this way, Gleiser argues, is not a deterrent to progress or a surrendering to religion. Rather, it frees us to question the meaning and nature of the universe while affirming the central role of life and ourselves in it. Science can and must go on, but recognizing its limits reveals its true mission: to know the universe is to know ourselves. Telling the dramatic story of our quest for understanding, The Island of Knowledge offers a highly original exploration of the ideas of some of the greatest thinkers in history, from Plato to Einstein, and how they affect us today. An authoritative, broad-ranging intellectual history of our search for knowledge and meaning, The Island of Knowledge is a unique view of what it means to be human in a universe filled with mystery.
The Wolf Border
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Author : Sarah Hall
language : en
Publisher: Faber & Faber
Release Date : 2015-03-24
The Wolf Border written by Sarah Hall and has been published by Faber & Faber this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-24 with Fiction categories.
'One of the finest writers at work today.' Damon Galgut 'A writer of show-stopping genius.' Guardian 'So vivid, so visceral, so vital.' Val McDermid For almost a decade Rachel Caine has turned her back on home and worked in Idaho at a reservation for wolves. As one of the few experts in her field she is summoned back to England by the eccentric Earl of Annerdale to help with his plan for re-wilding wolves on his estate in the Lake District. As Rachel attempts a gradual reconciliation with her estranged family, her work with the Earl begins to generate public outrage and the threat of sabotage. Set against a backdrop of Scottish independence and tumultuous power struggles both locally and nationally, The Wolf Border is a novel steeped in wilderness and wildness, both animal and human. 'A graceful, visceral, utterly compelling read.' Sunday Express magazine 'A thrilling tale of politics and power . . . Compulsively absorbing and masterfully plotted, it confirms Hall as one of our finest fiction writers.' Daily Mail 'A compelling, psychological drama . . . [Hall] has a golden touch.' The Economist
Problems In Syntax
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Author : Liliane Tasmowski
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Problems In Syntax written by Liliane Tasmowski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Language Arts & Disciplines categories.
Social Representations For The Anthropocene Latin American Perspectives
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Author : Clarilza Prado de Sousa
language : en
Publisher: Springer Nature
Release Date : 2021-04-30
Social Representations For The Anthropocene Latin American Perspectives written by Clarilza Prado de Sousa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-30 with Science categories.
The Anthropocene has become a field of studies in which the influence of human activity on the Earth System and nature is both the main threat and the potential solution. Social Representations Theory has been evolving since the 1960s.It links knowledge and practice in everyday life and is an effective way to deal with systemic crises based on common sense. This book assembles key contributions by Latin American scholars working with social representations in the social sciences that are of conceptual relevance to the study of the Anthropocene and that investigate the societal consequences of complex interrelations between common sense and topics of global relevance, such asthe contradictions of sustainable development, the construction of risks beyond risk-perception, health, negotiation and governance in the field of education, gender equality, the usefulness of longitudinal and systemic ethnography and case studies, and agency and the link between inequality, crises and risk society in the context of COVID-19, presenting theoretical and methodological innovations fromSpanish, Portuguese and Frenchresearchthat have rarely been available in English. • This is the first book to address the relevance of Social Representations Theory for the Anthropocene as a societal era• It presents the multidisciplinary scope of Social Representations• This book covers emerging research contributions in Social Representations Theory from Latin America• This book presents innovative research and commentaries by established researchers in the field• This multidisciplinary book should be in the libraries of many disciplines in the social sciences and humanities
Principles For Building Resilience
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Author : Reinette Biggs
language : en
Publisher: Cambridge University Press
Release Date : 2015-04-02
Principles For Building Resilience written by Reinette Biggs and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-02 with Business & Economics categories.
Reflecting the very latest research, this book provides an in-depth review of the role of resilience in the management of social-ecological systems and the ecosystem services they provide. Leaders in the field outline seven principles for building resilience in social-ecological systems, examining how these can be applied to advance sustainability.
Reflections On Translation
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Author : Susan Bassnett
language : en
Publisher: Multilingual Matters
Release Date : 2011
Reflections On Translation written by Susan Bassnett and has been published by Multilingual Matters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Language Arts & Disciplines categories.
This collection of essays brings together a decade of writings on translation by leading international translation studies expert, Susan Bassnett. The essays cover a range of topics and will be useful to anyone with an interest in how different cultures communicate.
Death And The King S Horseman
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Author : Wole Soyinka
language : en
Publisher: Methuen Drama
Release Date : 2016-01-28
Death And The King S Horseman written by Wole Soyinka and has been published by Methuen Drama this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-28 with Drama categories.
Elesin Oba, the King's Horseman, has a single destiny. When the King dies, he must commit ritual suicide and lead his King's favourite horse and dog through the passage to the world of the ancestors. A British Colonial Officer, Pilkings, intervenes to prevent the death and arrests Elesin. The play is a set text for NEAB GCSE, NEAB A Level and NEAB A/S Level. 'A masterpiece of 20th century drama' - Guardian "A transfixing work of modern world drama" (Independent); "clearly a masterpiece. . . he achieves the full impact of Greek tragedy" (Irving Wardle, Independent on Sunday); "the action of the play is as inevitable and eloquent as in Antigone: a clash of values and cultures so fundamental that tragedy issues: a tragedy for each individual, each tribe" (Michael Schmidt, Daily Telegraph)