Semisynthesis Of Bioactive Compounds And Their Biological Activities

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Semisynthesis Of Bioactive Compounds And Their Biological Activities

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Author : Sasadhar Majhi
language : en
Publisher: Elsevier
Release Date : 2023-11-25

Semisynthesis Of Bioactive Compounds And Their Biological Activities written by Sasadhar Majhi and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-25 with Science categories.

Semisynthesis of Bioactive Compounds and their Biological Activities explores the potential benefits of semisynthetic derivatives obtained from nature. Sections cover the natural distribution of parent compounds, semisynthesis and biological properties of semisynthetic derivatives, the applications of semisynthetic derivatives in diverse fields such as drug delivery, food production and medicine, an explanation of the current resistance mechanisms of antibiotics, clinical applications of semisynthetic analogues, the functions of plant alkaloids on human health, potential agricultural biotechnology in semisynthetic derivatives, and semisynthesis of natural products under greener conditions, this book provides a comprehensive resource on the topics presented. Sections include information about alternative sources of energy and superior greener technologies (microwave, sonochemistry), alternative reaction media (water, supercritical CO2, ionic liquids) and alternative eco-friendly catalysts (biocatalysts). This book will be an excellent resource for academicians, researchers and students focusing on synthesis as well as the biological community and industry professionals in drug development. - Focuses on the current resistance mechanisms of antibiotics, chemical derivatization of antibiotics, and clinical applications of semisynthetic derivatives. - Includes discussion of the semisynthesis of natural products using green tools, green solvents, and eco-friendly catalysts. - Illustrates the concept of toxicity, the merits of transition-metal-free reactions, and the semisynthesis of natural products by introducing the oxygen atom(s) under transition-metal-free conditions.

Bioactive Three Membered Heterocycles

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Author : Dilip Kumar Maiti
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2025-04-21

Bioactive Three Membered Heterocycles written by Dilip Kumar Maiti and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-21 with Science categories.

Bioactive Three-Membered Heterocycles provides detailed information on the green synthesis of the structurally diverse pharmaceutically active three-membered heterocycles. It covers both synthesis and biological aspects and highlights the role of three-membered heterocycles in drugs and drug designing. It also includes naturally occurring bioactive three-membered heterocycles.

Carbohydrates In Chemistry And Biology

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Author : Vinod Kumar Tiwari
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2025-04-21

Carbohydrates In Chemistry And Biology written by Vinod Kumar Tiwari and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-21 with Science categories.

Carbohydrates in Chemistry and Biology provides detailed information about the green synthesis, biological importance and catalytic applications of carbohydrate derivatives. It covers various topics including carbohydrate decorated compounds, bioconjugation, carbohydrate functionalized heterocycles, carbohydrate-spiro-heterocycles, heterocycles from carbohydrate precursors and natural sources of bioactive carbohydrates.

Bioactive Four Membered Heterocycles

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Author : Jitender Mohan Khurana
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2025-04-21

Bioactive Four Membered Heterocycles written by Jitender Mohan Khurana and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-21 with Science categories.

Bioactive Four-Membered Heterocycles provides detailed information on the green synthesis of the structurally diverse pharmaceutically active four-membered heterocycles. It covers both synthesis and biological aspects and highlights the role of four-membered heterocycles in drugs and drug designing. It also includes naturally occurring bioactive four-membered heterocycles.

Chemistry And Pharmacology Of Naturally Occurring Bioactive Compounds

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Author : Goutam Brahmachari
language : en
Publisher: CRC Press
Release Date : 2013-02-20

Chemistry And Pharmacology Of Naturally Occurring Bioactive Compounds written by Goutam Brahmachari and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-20 with Medical categories.

Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. In 21 chapters, this book highlights chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, the book features chemical advances in naturally occurring organic compounds and describes their chemical transformations and structure–activity relationships.

Bioactive Natural Products

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Author : Goutam Brahmachari
language : en
Publisher: John Wiley & Sons
Release Date : 2015-03-23

Bioactive Natural Products written by Goutam Brahmachari and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-23 with Science categories.

Ein multidisziplinärer Überblick über die aktuellen Themen und Zukunftstrends in der Erforschung von Naturstoffen mit Schwerpunkt auf pharmazeutischen und medizinischen Anwendungen.

Studies In Natural Products Chemistry

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Author : Atta-ur- Rahman
language : en
Publisher: Elsevier
Release Date : 2012-12-31

Studies In Natural Products Chemistry written by Atta-ur- Rahman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. - Describes the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - A valuable resource for natural product and medicinal chemistry

Bioactive Natural Products

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Author : Goutam Brahmachari
language : en
Publisher: John Wiley & Sons
Release Date : 2015-01-20

Bioactive Natural Products written by Goutam Brahmachari and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-20 with Science categories.

Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.

Drug Discovery In Africa

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Author : Kelly Chibale
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-08-09

Drug Discovery In Africa written by Kelly Chibale and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-09 with Science categories.

Drug discovery originating in Africa has the potential to provide significantly improved treatment of endemic diseases such as malaria, tuberculosis and HIV/AIDS. This book critically reviews the current status of drug discovery research and development in Africa, for diseases that are a major threat to the health of people living in Africa. Compiled by leading African and international experts, this book presents the science and strategies of modern drug discovery. It explores how the use of natural products and traditional medicines can benefit from conventional drug discovery approaches, and proposes solutions to current technological, infrastructural, human resources, and economic challenges, which are presented when attempting to engage in full-scale drug discovery. Topics addressed are varied; from African medicinal plants to marine bioprospecting, pharmacogenetics and the use of nanotechnology. This book brings together for the first time a collection of strategies and techniques that need to be considered when developing drugs in an African setting. It is an unprecedented and truly international effort, highlighting the remarkable effort made so far in the area of drug discovery research by African scientists, and scientists from other parts of the world working on African health problems.

Total Synthesis Of Bioactive Natural Products

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Author : Goutam Brahmachari
language : en
Publisher: Elsevier
Release Date : 2019-04-27

Total Synthesis Of Bioactive Natural Products written by Goutam Brahmachari and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-27 with Science categories.

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products. - Provides individual outlines for the total synthesis of approximately 100 bioactive natural molecules - Outlines each step of the process in detail, with full experimental information supported by extensive schemes - Includes retrosynthetic analyses, reaction sequences and stereochemically crucial steps for each molecule