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Sensitivity Analysis


Sensitivity Analysis
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Sensitivity Analysis


Sensitivity Analysis
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Author : Emanuele Borgonovo
language : en
Publisher: Springer
Release Date : 2017-04-19

Sensitivity Analysis written by Emanuele Borgonovo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-19 with Business & Economics categories.


This book is an expository introduction to the methodology of sensitivity analysis of model output. It is primarily intended for investigators, students and researchers that are familiar with mathematical models but are less familiar with the techniques for performing their sensitivity analysis. A variety of sensitivity methods have been developed over the years. This monograph helps the analyst in her/his first exploration of this world. The main goal is to foster the recognition of the crucial role of sensitivity analysis methods as the techniques that allow us to gain insights from quantitative models. Also, exercising rigor in performing sensitivity analysis becomes increasingly relevant both to decision makers and modelers. The book helps the analyst in structuring her/his sensitivity analysis quest properly, so as to obtain the correct answer to the corresponding managerial question. The first part of the book covers Deterministic Methods, including Tornado Diagrams; One-Way Sensitivity Analysis; Differentiation-Based Methods and Local Sensitivity Analysis with Constraints. The second part looks at Probabilistic Methods, including Regression-Based methods, Variance-Based Methods, and Distribution-Based methods. The final section looks at Applications, including capital budgeting, sensitivity analysis in climate change modelling and in the risk assessment of a lunar space mission.



Sensitivity Analysis In Practice


Sensitivity Analysis In Practice
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Author : A. Saltelli
language : en
Publisher: John Wiley & Sons
Release Date : 2004-04-02

Sensitivity Analysis In Practice written by A. Saltelli and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-02 with Computers categories.


Sensitivity analysis is the study of how variation in the output of a statistical model can be apportioned, qualitatively or quantitatively, to different sources of variation. This work allows applied scientists to choose and apply the most appropriate sensitivity analysis method.



Sensitivity Analysis Matrix Methods In Demography And Ecology


Sensitivity Analysis Matrix Methods In Demography And Ecology
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Author : Hal Caswell
language : en
Publisher: Springer
Release Date : 2019-04-02

Sensitivity Analysis Matrix Methods In Demography And Ecology written by Hal Caswell and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-02 with Social Science categories.


This open access book shows how to use sensitivity analysis in demography. It presents new methods for individuals, cohorts, and populations, with applications to humans, other animals, and plants. The analyses are based on matrix formulations of age-classified, stage-classified, and multistate population models. Methods are presented for linear and nonlinear, deterministic and stochastic, and time-invariant and time-varying cases. Readers will discover results on the sensitivity of statistics of longevity, life disparity, occupancy times, the net reproductive rate, and statistics of Markov chain models in demography. They will also see applications of sensitivity analysis to population growth rates, stable population structures, reproductive value, equilibria under immigration and nonlinearity, and population cycles. Individual stochasticity is a theme throughout, with a focus that goes beyond expected values to include variances in demographic outcomes. The calculations are easily and accurately implemented in matrix-oriented programming languages such as Matlab or R. Sensitivity analysis will help readers create models to predict the effect of future changes, to evaluate policy effects, and to identify possible evolutionary responses to the environment. Complete with many examples of the application, the book will be of interest to researchers and graduate students in human demography and population biology. The material will also appeal to those in mathematical biology and applied mathematics.



Developing A Protocol For Observational Comparative Effectiveness Research A User S Guide


Developing A Protocol For Observational Comparative Effectiveness Research A User S Guide
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Author : Agency for Health Care Research and Quality (U.S.)
language : en
Publisher: Government Printing Office
Release Date : 2013-02-21

Developing A Protocol For Observational Comparative Effectiveness Research A User S Guide written by Agency for Health Care Research and Quality (U.S.) and has been published by Government Printing Office this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-21 with Medical categories.


This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)



Sensitivity Analysis For Neural Networks


Sensitivity Analysis For Neural Networks
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Author : Daniel S. Yeung
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-09

Sensitivity Analysis For Neural Networks written by Daniel S. Yeung and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-09 with Computers categories.


Artificial neural networks are used to model systems that receive inputs and produce outputs. The relationships between the inputs and outputs and the representation parameters are critical issues in the design of related engineering systems, and sensitivity analysis concerns methods for analyzing these relationships. Perturbations of neural networks are caused by machine imprecision, and they can be simulated by embedding disturbances in the original inputs or connection weights, allowing us to study the characteristics of a function under small perturbations of its parameters. This is the first book to present a systematic description of sensitivity analysis methods for artificial neural networks. It covers sensitivity analysis of multilayer perceptron neural networks and radial basis function neural networks, two widely used models in the machine learning field. The authors examine the applications of such analysis in tasks such as feature selection, sample reduction, and network optimization. The book will be useful for engineers applying neural network sensitivity analysis to solve practical problems, and for researchers interested in foundational problems in neural networks.



The Prevention And Treatment Of Missing Data In Clinical Trials


The Prevention And Treatment Of Missing Data In Clinical Trials
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2010-12-21

The Prevention And Treatment Of Missing Data In Clinical Trials written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-21 with Medical categories.


Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.



Sensitivity Analysis In Earth Observation Modelling


Sensitivity Analysis In Earth Observation Modelling
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Author : George P. Petropoulos
language : en
Publisher: Elsevier
Release Date : 2016-10-07

Sensitivity Analysis In Earth Observation Modelling written by George P. Petropoulos and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-07 with Science categories.


Sensitivity Analysis in Earth Observation Modeling highlights the state-of-the-art in ongoing research investigations and new applications of sensitivity analysis in earth observation modeling. In this framework, original works concerned with the development or exploitation of diverse methods applied to different types of earth observation data or earth observation-based modeling approaches are included. An overview of sensitivity analysis methods and principles is provided first, followed by examples of applications and case studies of different sensitivity/uncertainty analysis implementation methods, covering the full spectrum of sensitivity analysis techniques, including operational products. Finally, the book outlines challenges and future prospects for implementation in earth observation modeling. Information provided in this book is of practical value to readers looking to understand the principles of sensitivity analysis in earth observation modeling, the level of scientific maturity in the field, and where the main limitations or challenges are in terms of improving our ability to implement such approaches in a wide range of applications. Readers will also be informed on the implementation of sensitivity/uncertainty analysis on operational products available at present, on global and continental scales. All of this information is vital in the selection process of the most appropriate sensitivity analysis method to implement. - Outlines challenges and future prospects of sensitivity analysis implementation in earth observation modeling - Provides readers with a roadmap for directing future efforts - Includes case studies with applications from different regions around the globe, helping readers to explore strengths and weaknesses of the different methods in earth observation modeling - Presents a step-by-step guide, providing the principles of each method followed by the application of variants, making the reference easy to use and follow



Numerical Methods In Sensitivity Analysis And Shape Optimization


Numerical Methods In Sensitivity Analysis And Shape Optimization
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Author : Emmanuel Laporte
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-12-13

Numerical Methods In Sensitivity Analysis And Shape Optimization written by Emmanuel Laporte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-13 with Mathematics categories.


Sensitivity analysis and optimal shape design are key issues in engineering that have been affected by advances in numerical tools currently available. This book, and its supplementary online files, presents basic optimization techniques that can be used to compute the sensitivity of a given design to local change, or to improve its performance by local optimization of these data. The relevance and scope of these techniques have improved dramatically in recent years because of progress in discretization strategies, optimization algorithms, automatic differentiation, software availability, and the power of personal computers. Numerical Methods in Sensitivity Analysis and Shape Optimization will be of interest to graduate students involved in mathematical modeling and simulation, as well as engineers and researchers in applied mathematics looking for an up-to-date introduction to optimization techniques, sensitivity analysis, and optimal design.



Global Sensitivity Analysis


Global Sensitivity Analysis
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Author : A. Saltelli
language : en
Publisher: Wiley-Interscience
Release Date : 2008-02-11

Global Sensitivity Analysis written by A. Saltelli and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-11 with Mathematics categories.


Complex mathematical and computational models are used in all areas of society and technology and yet model based science is increasingly contested or refuted, especially when models are applied to controversial themes in domains such as health, the environment or the economy. More stringent standards of proofs are demanded from model-based numbers, especially when these numbers represent potential financial losses, threats to human health or the state of the environment. Quantitative sensitivity analysis is generally agreed to be one such standard. Mathematical models are good at mapping assumptions into inferences. A modeller makes assumptions about laws pertaining to the system, about its status and a plethora of other, often arcane, system variables and internal model settings. To what extent can we rely on the model-based inference when most of these assumptions are fraught with uncertainties? Global Sensitivity Analysis offers an accessible treatment of such problems via quantitative sensitivity analysis, beginning with the first principles and guiding the reader through the full range of recommended practices with a rich set of solved exercises. The text explains the motivation for sensitivity analysis, reviews the required statistical concepts, and provides a guide to potential applications. The book: Provides a self-contained treatment of the subject, allowing readers to learn and practice global sensitivity analysis without further materials. Presents ways to frame the analysis, interpret its results, and avoid potential pitfalls. Features numerous exercises and solved problems to help illustrate the applications. Is authored by leading sensitivity analysis practitioners, combining a range of disciplinary backgrounds. Postgraduate students and practitioners in a wide range of subjects, including statistics, mathematics, engineering, physics, chemistry, environmental sciences, biology, toxicology, actuarial sciences, and econometrics will find much of use here. This book will prove equally valuable to engineers working on risk analysis and to financial analysts concerned with pricing and hedging.



Sensitivity Analysis In Linear Regression


Sensitivity Analysis In Linear Regression
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Author : Samprit Chatterjee
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-25

Sensitivity Analysis In Linear Regression written by Samprit Chatterjee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-25 with Mathematics categories.


Treats linear regression diagnostics as a tool for application of linear regression models to real-life data. Presentation makes extensive use of examples to illustrate theory. Assesses the effect of measurement errors on the estimated coefficients, which is not accounted for in a standard least squares estimate but is important where regression coefficients are used to apportion effects due to different variables. Also assesses qualitatively and numerically the robustness of the regression fit.