Serine Proteases And Their Serpin Inhibitors In The Nervous System
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Serine Proteases And Their Serpin Inhibitors In The Nervous System
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Author : Barry W. Festoff
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Serine Proteases And Their Serpin Inhibitors In The Nervous System written by Barry W. Festoff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Proceedings of a NATO ARW held in Maratea, Italy, July 2-8, 1989
Serine Proteases And Their Serpin Inhibitors In The Nervous System
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Author : Barry W Festoff
language : en
Publisher:
Release Date : 1990-09-30
Serine Proteases And Their Serpin Inhibitors In The Nervous System written by Barry W Festoff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-09-30 with categories.
Proteases In Human Diseases
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Author : Sajal Chakraborti
language : en
Publisher: Springer
Release Date : 2017-07-13
Proteases In Human Diseases written by Sajal Chakraborti and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-13 with Medical categories.
This book bridges the gap between fundamental research and biomedical and pharmacological applications on proteases. It represents a comprehensive overview of the multifaceted field of proteases in cellular environment and highlights the recently elucidated functions of complex proteolytic systems in different diseases. Several established investigators have elucidated the crucial role of proteases in biological processes, including how proteolytic function and regulation can be combined to develop new strategies of therapeutic interventions. Proteases form one of the largest and most diverse families of enzymes known. It is now clear that proteases are involved in every aspect of life functions of an organism. Under physiological conditions, proteases are regulated by their endogenous inhibitors; however, when the activity of proteases is not regulated appropriately, disease processes can result in. So, there is absolute need for a stringent control of proteolytic activities in cells and tissues. Dysregulation of proteases may cause derangement of cellular signalling network resulting in different pathophysiological conditions such as vascular remodelling, atherosclerotic plaque progression, ulcer and rheumatoid arthritis, Alzheimer disease, cancer metastasis, tumor progression and inflammation. Additionally, many infective microorganisms require proteases for replication or use proteases as virulence factors, which have facilitated the development of protease-targeted therapies for a variety of parasitic diseases.
Handbook Of Neurochemistry And Molecular Neurobiology
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Author : Abel Lajtha
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-26
Handbook Of Neurochemistry And Molecular Neurobiology written by Abel Lajtha and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-26 with Medical categories.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1991
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medicine categories.
First multi-year cumulation covers six years: 1965-70.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1995
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Medicine categories.
Antithrombotics
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Author : Andrew C.G. Uprichard
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Antithrombotics written by Andrew C.G. Uprichard and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
An up-to-date overview of blood coagulation, hemostatis, and thrombosis, this volume also provides a state-of-the-art report of current anti-thrombotic and anti-coagulant strategies as well as a summary of current research interest in the area and potential future targets. It attempts to balance traditional pharmacology with the newer sciences of molecular biology and in so doing, sets a framework for future advances in the field. The book is a concise, current and useful reference for the basic researcher as well as the practicing physician working in the fields of cardiology, internal medicine or surgery.
Brain Tumor Invasiveness
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Author : Ronald H. Goldfarb
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Brain Tumor Invasiveness written by Ronald H. Goldfarb and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
It is widely appreciated that the pathophysiology of advanced brain cancer is intimately related to the extent of tumor invasiveness. A prerequisite for comprehensively understanding neuro-oncology is therefore the elucidation of the biochemical and molecular properties of tumor cells that contribute to their invasiveness. An understanding of tumor invasion for central nervous system tumors is crucial since malignant brain tumors are very highly invasive and extensively destroy adjacent neural brain tissue. Moreover, they are angiogenesis-dependent and lead to the death of patients by expanding within the limited space of the cranium. As more specific insights are gained towards a full understanding of the complex process of tumor invasiveness of brain tumor cells, it should be possible to design strategies for the early diagnosis and treatment of invasive, advanced brain tumors. There is therefore an urgent need to better understand the cellular properties of brain tumor cells responsible for invasiveness. This special issue of the JOURNAL OF NEURO-ONCOLOGY provides a state-of-the-art review of the general understanding of the process of tumor invasion. In addition, the articles emphasize specific aspects of aggressive brain cancers which are particularly important for deriving new insights for therapeutic approaches for advanced brain cancer that will target tumor invasiveness. The ideas discussed will stimulate further studies directed towards the translation of these important invasion-related studies to clinical approaches for the effective treatment of brain cancer.
National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1991
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medicine categories.
Role Of Coagulation Pathways In Neurological Diseases
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Author : Tatiana Koudriavtseva
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-25
Role Of Coagulation Pathways In Neurological Diseases written by Tatiana Koudriavtseva and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-25 with categories.