Sex And Gender Differences In Pharmacology
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Sex And Gender Differences In Pharmacology
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Author : Vera Regitz-Zagrosek
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-02
Sex And Gender Differences In Pharmacology written by Vera Regitz-Zagrosek and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-02 with Medical categories.
A trailblazing assessment of sex and gender differences in reactions to drug therapy, this volume reflects the topic’s growing recognition. Analyses by international experts on both pharmacokinetics and drug development are informed by an extensive data set.
Sex And Gender Effects In Pharmacology
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Author : Stella E. Tsirka
language : en
Publisher: Springer Nature
Release Date : 2023-11-12
Sex And Gender Effects In Pharmacology written by Stella E. Tsirka and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-12 with Medical categories.
Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
Sex And Gender Differences In Infection And Treatments For Infectious Diseases
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Author : Sabra L. Klein
language : en
Publisher: Springer Nature
Release Date : 2023-09-11
Sex And Gender Differences In Infection And Treatments For Infectious Diseases written by Sabra L. Klein and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-11 with Medical categories.
This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).
Drug Discovery And Evaluation Methods In Clinical Pharmacology
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Author : H.Gerhard Vogel
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-15
Drug Discovery And Evaluation Methods In Clinical Pharmacology written by H.Gerhard Vogel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-15 with Medical categories.
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Gender Difference In Diabetes
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Author : Giancarlo Tonolo
language : en
Publisher: Mdpi AG
Release Date : 2023-03-02
Gender Difference In Diabetes written by Giancarlo Tonolo and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-02 with categories.
Sex and gender can affect the incidence, prevalence, symptoms, course and response to drug therapy in many illnesses, with sex (the biological side) and gender (the social‒cultural one) being variously interconnected. During the two days of the meeting "Gender Differences in Diabetic Disease" held in Olbia, Italy, on 4 and 5 December 2020, we discussed the various medical, social, ethnic, psychological and anthropological aspects of gender differences to build as broad a picture as possible of how these differences are present and evident in diabetic disease. Type 2 diabetes is the perfect example to justify gender medicine. During the meeting, we also tried to identify the still-unclear points that deserve further studies. This book describes several aspects of gender medicine that are related to diabetes. Physiopathology, drug treatment, sexual and psychological aspects, diabetes complication, migration, burden of working with a chronic disease and aspects related to COVID-19 infection are explored in a gender differentiation way. The authors are from different fields: medical doctors, biologist, psychologist, nurse, pharmacist, anthropologist and so on.
Sex Gender And Substance Use
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Author : Lorraine Greaves
language : en
Publisher: MDPI
Release Date : 2021-04-14
Sex Gender And Substance Use written by Lorraine Greaves and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-14 with Medical categories.
“Sex, Gender and Substance Use” describes how both biological and social factors affect people's use of substances. There is a lot of research carried out on substance use, prevention and treatment in which sex and gender are missing. This book describes the concepts of sex and gender, what they mean and why including them in substance use research, practice and policy is vital. Substances such as alcohol, drugs, nicotine, and tobacco all have differential effects on females and males. Social and cultural gendered factors affect how women and men react to prevention, treatment and policies. The book includes numerous examples of how sex- and gender-sensitive research can increase our understanding and improve prevention and treatment, and why striving for gender-transformative substance use practice and research remains a gold standard.
How Sex And Gender Impact Clinical Practice
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Author : Marjorie R. Jenkins
language : en
Publisher: Academic Press
Release Date : 2020-12-02
How Sex And Gender Impact Clinical Practice written by Marjorie R. Jenkins and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-02 with Science categories.
How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges
Sex And Gender Aspects In Clinical Medicine
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Author : Sabine Oertelt-Prigione
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-15
Sex And Gender Aspects In Clinical Medicine written by Sabine Oertelt-Prigione and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-15 with Medical categories.
This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.
Gender Difference In Diabetes
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Author : Giancarlo Tonolo
language : en
Publisher:
Release Date : 2023
Gender Difference In Diabetes written by Giancarlo Tonolo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with categories.
Sex and gender can affect the incidence, prevalence, symptoms, course and response to drug therapy in many illnesses, with sex (the biological side) and gender (the social-cultural one) being variously interconnected. During the two days of the meeting "Gender Differences in Diabetic Disease" held in Olbia, Italy, on 4 and 5 December 2020, we discussed the various medical, social, ethnic, psychological and anthropological aspects of gender differences to build as broad a picture as possible of how these differences are present and evident in diabetic disease. Type 2 diabetes is the perfect example to justify gender medicine. During the meeting, we also tried to identify the still-unclear points that deserve further studies. This book describes several aspects of gender medicine that are related to diabetes. Physiopathology, drug treatment, sexual and psychological aspects, diabetes complication, migration, burden of working with a chronic disease and aspects related to COVID-19 infection are explored in a gender differentiation way. The authors are from different fields: medical doctors, biologist, psychologist, nurse, pharmacist, anthropologist and so on.
Sex And Gender Differences In Alzheimer S Disease
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Author : Maria Teresa Ferretti
language : en
Publisher: Academic Press
Release Date : 2021-07-23
Sex And Gender Differences In Alzheimer S Disease written by Maria Teresa Ferretti and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-23 with Medical categories.
Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews: "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer’s disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspired Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel
