Signal Transduction And Smooth Muscle
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Signal Transduction And Smooth Muscle
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Author : Mohamed Trebak
language : en
Publisher: CRC Press
Release Date : 2018-08-06
Signal Transduction And Smooth Muscle written by Mohamed Trebak and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-06 with Medical categories.
All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling. Key selling features: Focuses on smooth muscles of different types Describes ion channel signaling mechanisms Reviews calcium and receptor signaling Includes novel, cutting-edge methodologies Summarizes studies of mice with genetically encoding sensors in smooth muscle Chapter 9 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution (CC-BY) 4.0 license.
Cellular Aspects Of Smooth Muscle Function
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Author : C. Y. Kao
language : en
Publisher: Cambridge University Press
Release Date : 1997-08-28
Cellular Aspects Of Smooth Muscle Function written by C. Y. Kao and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-08-28 with Medical categories.
Smooth muscles line many internal organs and, in general, are involved in moving fluids and slurry around the body. They are controlled by the action of hormones, by nervous stimulation, and can be influenced by drugs. This 1997 book provides a review of our understanding of smooth muscle and integrates molecular, cellular and physiological information with tissue and anatomical studies. Well-known researchers have written chapters giving detailed reviews of our current knowledge of the biochemistry, pharmacology, physiology and anatomy of smooth muscle. In particular, they cover the seven most important areas of smooth muscle function including morphology, electrophysiology, mechanisms of electromechanical and pharmacomechanical coupling, calcium homeostasis, signal transduction, mechanics of contraction, and the contractile proteins. All those interested in muscular contraction will find this book worthwhile, whether they are biochemists, physiologists, or cell biologists.
Cardiovascular Physiology Concepts
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Author : Richard E. Klabunde
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2005
Cardiovascular Physiology Concepts written by Richard E. Klabunde and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
This uniquely readable, compact, and concise monograph lays a foundation of knowledge of the underlying concepts of normal cardiovascular function. Students welcome the book's broad overview as a practical partner or alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Especially clear explanations, ample illustrations, a helpful glossary of terms, tutorials, and chapter-opening learning objectives provide superb guidance for self-directed learning and help fill the gap in many of today's abbreviated physiology blocks. A focus on well-established cardiovascular principles reflects recent, widely accepted cardiovascular research. The supplemental CD-ROM is an interactive, dynamically linked version of the book, which is organized by normal cardiovascular function and cardiac disease. Students may begin a path of questioning with, for example, a disease condition and then pursue background information through a series of links. Students can also link to the author's regularly updated Web site for additional clinical information.
Encyclopedic Reference Of Molecular Pharmacology
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Author : Stefan Offermanns
language : en
Publisher:
Release Date : 2004
Encyclopedic Reference Of Molecular Pharmacology written by Stefan Offermanns and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.
Mechanisms Of Vascular Disease
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Author : Robert Fitridge
language : en
Publisher: University of Adelaide Press
Release Date : 2011
Mechanisms Of Vascular Disease written by Robert Fitridge and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Signal Transduction
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Author : Bastien D. Gomperts
language : en
Publisher: Gulf Professional Publishing
Release Date : 2003-10-15
Signal Transduction written by Bastien D. Gomperts and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-15 with Medical categories.
Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
Smooth Muscle Excitation
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Author : T. B. Bolton
language : en
Publisher:
Release Date : 1996
Smooth Muscle Excitation written by T. B. Bolton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
This book is a compendium of the latest electrophysiological research on smooth muscles from an international collection of authors. It includes recent discoveries in calcium stores and their relationship to contraction and to electrical changes in the membrane. A major section of the book concentrates on calcium release mechanisms in the cell, their control, and the consequences of calcium release in the cell for membrane events. Smooth Muscle Excitation also covers the effects of chemicals released from adjacent cells. Key Features * State-of-the-art volume that represents a synopsis of all work currently being undertaken in this area throughout the world * Content covers both basic and clinical research * Provides a range of drug development studies * Presents contributions from many internationally recognized smooth muscle physiologists
Oxidative Stress And Signal Transduction
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Author : H.J. Forman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Oxidative Stress And Signal Transduction written by H.J. Forman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constituents. There is now evidence that reactive oxygen species (ROS) can alter cell function by acting upon the intermediates, or second messengers, in signal transductions. Such effects on signaling mechanisms probably account for the role of oxidative stress in inflammation, aging, and cancer. This volume brings together internationally recognized researchers in both the major areas covered by the book, oxidative stress and signal transduction. The work is organized in three sections. The first deals with the immediate cellular responses to oxidative stress and the production of second messengers. The second details the connection between second messengers and the gene. The third part looks more closely at the level of the gene.
Vascular Ion Channels In Physiology And Disease
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Author : Irena Levitan, PhD
language : en
Publisher: Springer
Release Date : 2016-07-06
Vascular Ion Channels In Physiology And Disease written by Irena Levitan, PhD and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-06 with Medical categories.
Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a variety of cell types. This book focuses on the roles of ion channels in vascular tissues under normal and pathological conditions. Vascular abnormalities are known to underlie a plethora of severe pathological conditions, such as atherosclerosis, systemic and pulmonary hypertension, coronary or cerebral vasospasm, and diabetes. In addition, misregulated angiogenesis is one of the major contributors to the development of tumors. Therefore, it is clearly imperative to obtain a better understanding of the molecular mechanisms that contribute to vascular disorders. This book will be the first comprehensive assembly of assays to present the studies that have been done during the last decade to elucidate the roles of ion channels in different vascular diseases.