Single Neuron Computation
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Biophysics Of Computation
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Author : Christof Koch
language : en
Publisher: Oxford University Press
Release Date : 2004-10-28
Biophysics Of Computation written by Christof Koch and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-28 with Medical categories.
Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.
Single Neuron Computation
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Author : Thomas M. McKenna
language : en
Publisher: Academic Press
Release Date : 2014-05-19
Single Neuron Computation written by Thomas M. McKenna and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-19 with Computers categories.
This book contains twenty-two original contributions that provide a comprehensive overview of computational approaches to understanding a single neuron structure. The focus on cellular-level processes is twofold. From a computational neuroscience perspective, a thorough understanding of the information processing performed by single neurons leads to an understanding of circuit- and systems-level activity. From the standpoint of artificial neural networks (ANNs), a single real neuron is as complex an operational unit as an entire ANN, and formalizing the complex computations performed by real neurons is essential to the design of enhanced processor elements for use in the next generation of ANNs.The book covers computation in dendrites and spines, computational aspects of ion channels, synapses, patterned discharge and multistate neurons, and stochastic models of neuron dynamics. It is the most up-to-date presentation of biophysical and computational methods.
From Neuron To Cognition Via Computational Neuroscience
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Author : Michael A. Arbib
language : en
Publisher: MIT Press
Release Date : 2016-11-04
From Neuron To Cognition Via Computational Neuroscience written by Michael A. Arbib and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-04 with Science categories.
A comprehensive, integrated, and accessible textbook presenting core neuroscientific topics from a computational perspective, tracing a path from cells and circuits to behavior and cognition. This textbook presents a wide range of subjects in neuroscience from a computational perspective. It offers a comprehensive, integrated introduction to core topics, using computational tools to trace a path from neurons and circuits to behavior and cognition. Moreover, the chapters show how computational neuroscience—methods for modeling the causal interactions underlying neural systems—complements empirical research in advancing the understanding of brain and behavior. The chapters—all by leaders in the field, and carefully integrated by the editors—cover such subjects as action and motor control; neuroplasticity, neuromodulation, and reinforcement learning; vision; and language—the core of human cognition. The book can be used for advanced undergraduate or graduate level courses. It presents all necessary background in neuroscience beyond basic facts about neurons and synapses and general ideas about the structure and function of the human brain. Students should be familiar with differential equations and probability theory, and be able to pick up the basics of programming in MATLAB and/or Python. Slides, exercises, and other ancillary materials are freely available online, and many of the models described in the chapters are documented in the brain operation database, BODB (which is also described in a book chapter). Contributors Michael A. Arbib, Joseph Ayers, James Bednar, Andrej Bicanski, James J. Bonaiuto, Nicolas Brunel, Jean-Marie Cabelguen, Carmen Canavier, Angelo Cangelosi, Richard P. Cooper, Carlos R. Cortes, Nathaniel Daw, Paul Dean, Peter Ford Dominey, Pierre Enel, Jean-Marc Fellous, Stefano Fusi, Wulfram Gerstner, Frank Grasso, Jacqueline A. Griego, Ziad M. Hafed, Michael E. Hasselmo, Auke Ijspeert, Stephanie Jones, Daniel Kersten, Jeremie Knuesel, Owen Lewis, William W. Lytton, Tomaso Poggio, John Porrill, Tony J. Prescott, John Rinzel, Edmund Rolls, Jonathan Rubin, Nicolas Schweighofer, Mohamed A. Sherif, Malle A. Tagamets, Paul F. M. J. Verschure, Nathan Vierling-Claasen, Xiao-Jing Wang, Christopher Williams, Ransom Winder, Alan L. Yuille
Dynamic Clamp
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Author : Alain Destexhe
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-11
Dynamic Clamp written by Alain Destexhe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-11 with Medical categories.
Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons with computational models. The dynamic-clamp (also called “conductance injection”) allows experimentalists and theoreticians to challenge neurons (or any other type of cell) with complex conductance stimuli generated by a computer. The technique can be implemented from neural simulation environments and a variety of custom-made or commercial systems. The real-time interaction between the computer and cell also enables the design of recording paradigms with unprecedented accuracy via a computational model of the electrode. Dynamic-Clamp: From Principles to Applications contains contributions from leading researchers in the field, who investigate these paradigms at the cellular or network level, in vivo and in vitro, and in different brain regions and cardiac cells. Topics discussed include the addition of artificially-generated synaptic activity to neurons; adding, amplifying or neutralizing voltage-dependent conductances; creating hybrid networks with real and artificial cells; attaching simulated dendritic tree structures to the living cell; and connecting different neurons. This book will be of interest to experimental biophysicists, neurophysiologists, and cardiac physiologists, as well as theoreticians, engineers, and computational neuroscientists. Graduate and undergraduate students will also find up-to-date coverage of physiological problems and how they are investigated.
Deep Learning Models For Medical Imaging
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Author : KC Santosh
language : en
Publisher: Academic Press
Release Date : 2021-09-07
Deep Learning Models For Medical Imaging written by KC Santosh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-07 with Computers categories.
Deep Learning Models for Medical Imaging explains the concepts of Deep Learning (DL) and its importance in medical imaging and/or healthcare using two different case studies: a) cytology image analysis and b) coronavirus (COVID-19) prediction, screening, and decision-making, using publicly available datasets in their respective experiments. Of many DL models, custom Convolutional Neural Network (CNN), ResNet, InceptionNet and DenseNet are used. The results follow 'with' and 'without' transfer learning (including different optimization solutions), in addition to the use of data augmentation and ensemble networks. DL models for medical imaging are suitable for a wide range of readers starting from early career research scholars, professors/scientists to industrialists. - Provides a step-by-step approach to develop deep learning models - Presents case studies showing end-to-end implementation (source codes: available upon request)
Introduction To Lattice Algebra
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Author : Gerhard X. Ritter
language : en
Publisher: CRC Press
Release Date : 2021-08-23
Introduction To Lattice Algebra written by Gerhard X. Ritter and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-23 with Mathematics categories.
Lattice theory extends into virtually every branch of mathematics, ranging from measure theory and convex geometry to probability theory and topology. A more recent development has been the rapid escalation of employing lattice theory for various applications outside the domain of pure mathematics. These applications range from electronic communication theory and gate array devices that implement Boolean logic to artificial intelligence and computer science in general. Introduction to Lattice Algebra: With Applications in AI, Pattern Recognition, Image Analysis, and Biomimetic Neural Networks lays emphasis on two subjects, the first being lattice algebra and the second the practical applications of that algebra. This textbook is intended to be used for a special topics course in artificial intelligence with a focus on pattern recognition, multispectral image analysis, and biomimetic artificial neural networks. The book is self-contained and – depending on the student’s major – can be used for a senior undergraduate level or first-year graduate level course. The book is also an ideal self-study guide for researchers and professionals in the above-mentioned disciplines. Features Filled with instructive examples and exercises to help build understanding Suitable for researchers, professionals and students, both in mathematics and computer science Contains numerous exercises.
An Introduction To Neural Networks
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Author : James A. Anderson
language : en
Publisher: MIT Press
Release Date : 1995
An Introduction To Neural Networks written by James A. Anderson and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Computers categories.
An Introduction to Neural Networks falls into a new ecological niche for texts. Based on notes that have been class-tested for more than a decade, it is aimed at cognitive science and neuroscience students who need to understand brain function in terms of computational modeling, and at engineers who want to go beyond formal algorithms to applications and computing strategies. It is the only current text to approach networks from a broad neuroscience and cognitive science perspective, with an emphasis on the biology and psychology behind the assumptions of the models, as well as on what the models might be used for. It describes the mathematical and computational tools needed and provides an account of the author's own ideas. Students learn how to teach arithmetic to a neural network and get a short course on linear associative memory and adaptive maps. They are introduced to the author's brain-state-in-a-box (BSB) model and are provided with some of the neurobiological background necessary for a firm grasp of the general subject. The field now known as neural networks has split in recent years into two major groups, mirrored in the texts that are currently available: the engineers who are primarily interested in practical applications of the new adaptive, parallel computing technology, and the cognitive scientists and neuroscientists who are interested in scientific applications. As the gap between these two groups widens, Anderson notes that the academics have tended to drift off into irrelevant, often excessively abstract research while the engineers have lost contact with the source of ideas in the field. Neuroscience, he points out, provides a rich and valuable source of ideas about data representation and setting up the data representation is the major part of neural network programming. Both cognitive science and neuroscience give insights into how this can be done effectively: cognitive science suggests what to compute and neuroscience suggests how to compute it.
Calculus Of Thought
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Author : Daniel M Rice
language : en
Publisher: Academic Press
Release Date : 2013-10-15
Calculus Of Thought written by Daniel M Rice and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-15 with Mathematics categories.
Calculus of Thought: Neuromorphic Logistic Regression in Cognitive Machines is a must-read for all scientists about a very simple computation method designed to simulate big-data neural processing. This book is inspired by the Calculus Ratiocinator idea of Gottfried Leibniz, which is that machine computation should be developed to simulate human cognitive processes, thus avoiding problematic subjective bias in analytic solutions to practical and scientific problems. The reduced error logistic regression (RELR) method is proposed as such a "Calculus of Thought." This book reviews how RELR's completely automated processing may parallel important aspects of explicit and implicit learning in neural processes. It emphasizes the fact that RELR is really just a simple adjustment to already widely used logistic regression, along with RELR's new applications that go well beyond standard logistic regression in prediction and explanation. Readers will learn how RELR solves some of the most basic problems in today's big and small data related to high dimensionality, multi-colinearity, and cognitive bias in capricious outcomes commonly involving human behavior. - Provides a high-level introduction and detailed reviews of the neural, statistical and machine learning knowledge base as a foundation for a new era of smarter machines - Argues that smarter machine learning to handle both explanation and prediction without cognitive bias must have a foundation in cognitive neuroscience and must embody similar explicit and implicit learning principles that occur in the brain
The Neuron Book
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Author : Nicholas T. Carnevale
language : en
Publisher: Cambridge University Press
Release Date : 2006-01-12
The Neuron Book written by Nicholas T. Carnevale and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-12 with Medical categories.
The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.
Handbook Of Neural Computation
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Author : E Fiesler
language : en
Publisher: CRC Press
Release Date : 2020-01-15
Handbook Of Neural Computation written by E Fiesler and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-15 with Computers categories.
The Handbook of Neural Computation is a practical, hands-on guide to the design and implementation of neural networks used by scientists and engineers to tackle difficult and/or time-consuming problems. The handbook bridges an information pathway between scientists and engineers in different disciplines who apply neural networks to similar probl