Site Directed Modification Of Recombinant Antibody Fragments For In Vivo Fluorescence Imaging And Targeted Drug Delivery
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Site Directed Modification Of Recombinant Antibody Fragments For In Vivo Fluorescence Imaging And Targeted Drug Delivery
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Author : Florian Kampmeier
language : en
Publisher:
Release Date : 2010
Site Directed Modification Of Recombinant Antibody Fragments For In Vivo Fluorescence Imaging And Targeted Drug Delivery written by Florian Kampmeier and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Bio Engineering Approaches To Cancer Diagnosis And Treatment
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Author : Azadeh Shahidian
language : en
Publisher: Academic Press
Release Date : 2020-05-14
Bio Engineering Approaches To Cancer Diagnosis And Treatment written by Azadeh Shahidian and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-14 with Technology & Engineering categories.
Bioengineering Approaches to Cancer Diagnosis and Treatment is written for an audience of senior undergraduate students and graduate students in mechanical, electrical and biomedical engineering fields and other professionals in medicine. It is ideally structured for teaching and for those who are working in cancer bioengineering or interdisciplinary projects. The book's authors bring a unique perspective from their expertise in immunology, nanobiomaterials and heat transfer. Topical coverage includes an introduction to the fundamentals of bioengineering and engineering approaches for cancer diagnosis, cancer treatment via case studies, and sections on imaging, immunotherapy, cell therapy, drug delivery, ultrasound and microfluidics in cancer treatment. Provides fully supported case studies relating to cancer diagnosis and therapy Pairs the basic fundamentals of engineering and biomedical engineering and applies them to the diagnosis of cancer
Antibody Fusion Proteins
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Author : Steven M. Chamow
language : en
Publisher: Wiley-Liss
Release Date : 1999-04-13
Antibody Fusion Proteins written by Steven M. Chamow and has been published by Wiley-Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-04-13 with Science categories.
Thoroughly detailed and illustrated, this book examines the construction, properties, applications, and problems associated with specific types of fusion molecules used in clinical and research medicine. The editors present an overview of the field, followed by nine chapters divided into two general sections based on the two primary parts of the antibody molecule: Fab fusion proteins and Fc fusion proteins. In addition, numerous renowned scientists in the field have contributed outlines demonstrating man-made molecules that will be required not only to overcome the limitations of monoclonal antibodies, but also to extend the principle of selective targeting. Divided into specific, accessible sections, Antibody Fusion Proteins includes: * Chapters describing Fc fusion proteins, as well as several classes of antigen-binding proteins * Complete details on the design and molecular construction of genetically engineered fusion molecules * Useful information on molecular purification, large-scale production, practical applications, and their therapeutic potential * The latest data on forming fusion proteins with toxins, cytokines, or enzymes that can activate a prodrug
Functionalised Cardiovascular Stents
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Author : Gerard Wall
language : en
Publisher: Woodhead Publishing
Release Date : 2018-02-06
Functionalised Cardiovascular Stents written by Gerard Wall and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-06 with Medical categories.
Cardiovascular disease is a major cause of mortality in the western world and about half of these deaths are caused by coronary artery disease. One of the most commonly used interventions to treat arterial blockages is to deploy an arterial stent to keep the vessel open. Traditionally, some cardiovascular stents have been associated with serious side-effects, such as thrombosis. This book describes the fundamentals of cardiovascular stents, technologies to functionalize their surfaces and the market status of these important implants. The chapters provide specific focus on the production and evolution of cardiovascular stents, providing essential knowledge for researchers on advances in the field and knowledge of how cardiovascular stents are currently being "functionalized" in order to improve their biocompatibility and minimize negative outcomes in vivo. Provides a specific focus on cardiovascular stents Includes a range of topics covering the fundamentals, surface modification and biofunctionalization Provides essential knowledge for researchers on advances in the field
Protein Engineering
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Author : Huimin Zhao
language : en
Publisher: John Wiley & Sons
Release Date : 2021-08-23
Protein Engineering written by Huimin Zhao and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-23 with Science categories.
A one-stop reference that reviews protein design strategies to applications in industrial and medical biotechnology Protein Engineering: Tools and Applications is a comprehensive resource that offers a systematic and comprehensive review of the most recent advances in the field, and contains detailed information on the methodologies and strategies behind these approaches. The authors—noted experts on the topic—explore the distinctive advantages and disadvantages of the presented methodologies and strategies in a targeted and focused manner that allows for the adaptation and implementation of the strategies for new applications. The book contains information on the directed evolution, rational design, and semi-rational design of proteins and offers a review of the most recent applications in industrial and medical biotechnology. This important book: Covers technologies and methodologies used in protein engineering Includes the strategies behind the approaches, designed to help with the adaptation and implementation of these strategies for new applications Offers a comprehensive and thorough treatment of protein engineering from primary strategies to applications in industrial and medical biotechnology Presents cutting edge advances in the continuously evolving field of protein engineering Written for students and professionals of bioengineering, biotechnology, biochemistry, Protein Engineering: Tools and Applications offers an essential resource to the design strategies in protein engineering and reviews recent applications.
Current Developments In Biotechnology And Bioengineering
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Author : Vanete Thomaz Soccol
language : en
Publisher: Elsevier
Release Date : 2016-09-17
Current Developments In Biotechnology And Bioengineering written by Vanete Thomaz Soccol and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-17 with Science categories.
Current Developments in Biotechnology and Bioengineering: Human and Animal Health Applications provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, presenting data-based scientific knowledge and information on medical biotechnological interventions for human and animal health. Drawing on the key development areas in this field, the book reviews biotechnological advances and applications in immunotechnology, vaccines and vaccinology, combinatorial libraries, gene and cell therapy, tissue engineering, and parasite and infectious disease diagnostics. This title outlines why biotechnological techniques in these areas are useful in a clinical context and considers their potential uses, limitations, and the ethical considerations surrounding their use. Provides development in human and animal health due to biotechnology Includes immunotechnology and vaccinology Outlines diagnostic techniques based on tissue and metabolic engineering principles Considers potential uses of the various biotechnology based techniques and the ethical issues raised in their use
Advances In Photodynamic Therapy
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Author : Michael R. Hamblin
language : en
Publisher: Artech House
Release Date : 2008
Advances In Photodynamic Therapy written by Michael R. Hamblin and has been published by Artech House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
With today's focus on targeted and minimally invasive therapies, photodynamic therapy (PDT) is now being studied and used to combat many disease states and to investigate critical biological questions. This groundbreaking resource brings you the latest advances in photodynamic therapy and offers you a solid understanding of the design, delivery and dosimetry of the three basic ingredients of PDT - photosensitizers, light and oxygen. The book covers novel areas of mechanistic and innovative translational approaches. Moreover, it gives you an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.
Nanostructures For Drug Delivery
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Author : Ecaterina Andronescu
language : en
Publisher: Elsevier
Release Date : 2017-03-24
Nanostructures For Drug Delivery written by Ecaterina Andronescu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-24 with Medical categories.
Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial
Nanobiotechnology In Diagnosis Drug Delivery And Treatment
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Author : Mahendra Rai
language : en
Publisher: John Wiley & Sons
Release Date : 2020-11-17
Nanobiotechnology In Diagnosis Drug Delivery And Treatment written by Mahendra Rai and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-17 with Science categories.
Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.
Single Domain Antibodies
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Author : Dirk Saerens
language : en
Publisher: Humana Press
Release Date : 2012-08-10
Single Domain Antibodies written by Dirk Saerens and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-10 with Medical categories.
The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications. In Single Domain Antibodies: Methods and Protocols, expert researchers examine single variable domain antibody fragments, referred to as VH, VL, VHH or VNAR. These fragments are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.