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Sleep And Circadian Rhythms In Cancer Patients And Relationship With Quality Of Life


Sleep And Circadian Rhythms In Cancer Patients And Relationship With Quality Of Life
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Sleep And Circadian Rhythms In Cancer Patients And Relationship With Quality Of Life


Sleep And Circadian Rhythms In Cancer Patients And Relationship With Quality Of Life
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Author : Joy Perrier
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-02

Sleep And Circadian Rhythms In Cancer Patients And Relationship With Quality Of Life written by Joy Perrier and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-02 with Science categories.




Circadian Rhythm Disruption And Quality Of Life In Cancer Patients


Circadian Rhythm Disruption And Quality Of Life In Cancer Patients
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Author : Jamie K. Birris
language : en
Publisher:
Release Date : 2006

Circadian Rhythm Disruption And Quality Of Life In Cancer Patients written by Jamie K. Birris and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Cancer categories.


There is a growing body of research indicating that cancer patients have an increased risk of developing sleep disturbances caused by circadian rhythm disruption. Precipitating factors include psychological distress, treatment side effects and the cancer processes themselves, among others. Such sleep disturbances have serious deleterious effects on cancer patients' physical and emotional well-being. Sleep disturbances negatively affect immune functioning making it harder for cancer patients to protect themselves from infection and to fight off the cancer itself. In addition, sleep disturbances in cancer patients have been linked with poorer quality of life. This dissertation reviews the sleep process, sleep disturbances in the general population and sleep disturbances in cancer patients. It then explores the relationship between circadian rhythm disruption and quality of life in cancer patients through a study conducted with 24 cancer patients undergoing chemotherapy. Sleep disturbances were measured subjectively using the Pittsburgh Quality Sleep Index (PSQI) and objectively using the Sensewear Armband. Quality of life was measured using the Functional Assessment of Cancer Therapy - General (FACT-G). Correlational analysis results indicate that there is a significant correlation between the severity of cancer patients sleep disturbances and their global quality of life. More specifically, the physical and functional aspects of quality of life were more strongly correlated with the severity of sleep disturbances than the emotional and social aspects of quality of life. The current study results are discussed, as well as directions for further research.



Sleep And Clocks In Aging And Longevity


Sleep And Clocks In Aging And Longevity
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Author : Anita Jagota
language : en
Publisher: Springer Nature
Release Date : 2023-03-06

Sleep And Clocks In Aging And Longevity written by Anita Jagota and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-06 with Family & Relationships categories.


This edited volume focuses on the interplay between sleep and circadian rhythms with health, aging and longevity. Sleep is absolutely important for human health and survival, as insufficient sleep is associated with a plethora of conditions, including the poor quality of life, onset of several diseases, and premature death. The sleep–wake cycle is an evolutionary conserved neurobiological phenomenon, and is a prominent manifestation of the biological clocks localised in the suprachiasmatic nucleus (SCN). Understanding bidirectional relationship between sleep and circadian rhythms is of utmost importance and urgency, especially in the context of modern lifestyle where sleep is often out of phase with the internal body clocks, social jetlag, artificial lights and so on. The 25 chapters by leading researchers and experts from 11 countries are arranged into seven sections: understanding sleep and clock interlink in health and longevity; sleep, aging and longevity; clock, aging and longevity; melatonin, sleep and clock; genetic regulation of sleep and clock; therapeutic interventions in sleep disorders and clock misalignment; and experimental models to study sleep and clocks in aging and longevity. This book is useful for advanced undergraduate and graduate students, and researchers, educators, and other biomedical professionals.



Sleep And Quality Of Life In Clinical Medicine


Sleep And Quality Of Life In Clinical Medicine
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Author : Joris C. Verster
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-20

Sleep And Quality Of Life In Clinical Medicine written by Joris C. Verster and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-20 with Medical categories.


Many patients experience sleep disturbances secondary to their primary illness and this often has a negative effect on their quality of life. This book provides an evidence-based introduction to the interface between sleep wide range of medical disorders. A clinically focused, comprehensive review for physicians and other health providers, this state-of-the-art reference can also serve as a textbook for those who wish to become familiar with the impact of sleep on quality of life.



An Exploratory Study Of Sleep Wake Disturbances In Advanced Lung Cancer Patients


An Exploratory Study Of Sleep Wake Disturbances In Advanced Lung Cancer Patients
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Author : Claudette Yvonne Taylor
language : en
Publisher:
Release Date : 2015

An Exploratory Study Of Sleep Wake Disturbances In Advanced Lung Cancer Patients written by Claudette Yvonne Taylor and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Cancer categories.


ABSTRACT Sleep-wake disturbances are a common problem for people with cancer. Prior research of sleep-wake disturbances in cancer patients has focused predominantly on patients with early-stage disease. Consequently, little is known about sleep-wake disturbances in patients with advanced cancer. The significance of sleep-wake disturbances in advanced cancer patients and the factors associated with them is also not well understood. The purpose of this study was to identify the sleep-wake disturbances in individuals with advanced lung cancer and to explore the relationships amongst sleep, fatigue and quality of life in this population. All patients with newly diagnosed advanced non-small cell lung cancer attending outpatient clinics at the Cape Breton Cancer Centre (01/06/2013 to 30/06/2014) were invited to participate in the study. Seventy-two patients agreed to participate. Data were collected during the pre-treatment period. Questionnaires were used to collect symptoms, sleep quality, fatigue and quality of life data. Demographic and clinical data including co-morbidities, stage of disease and use of medications were collected from patients' medical charts. Data were analyzed using SPSS-21. Descriptive statistics were computed to describe the characteristics of the study sample and the study variables. Bivariate correlations amongst all study variables were conducted using Spearman's rho correlation coefficient. Multiple regression analyses were performed to examine the associations between the predictor variables. The conceptual framework that guided this study was the 'Borbely Two-Process Model of Sleep Regulation'. Borbely (1982) proposed two processes, a homeostatic process (Process S) and a circadian rhythm process (Process C) interact to regulate the timing and the duration of both sleep and wake states. A central hypothesis of this study was that Process S was influenced by mediator factors (i.e. pain, dyspnea) and psychological factors (i.e. anxiety). It was proposed that Process C was affected by moderator factors such as age and sex. Medications were proposed to affect both Process C and Process S. Findings showed that patients with advanced lung cancer experience very poor sleep quality and severe fatigue during the pre-treatment period. Difficulty initiating sleep, nocturnal sleep interruption, decreased sleep efficiency and daytime dysfunction were some of the experiences reported by patients. Difficulty starting and completing activities and requiring assistance with activities of daily living were reported because of severe fatigue. Poor sleep quality and severe fatigue predicted the quality of life of advanced lung cancer patients during the pre-treatment period. The relationship between sleep quality, fatigue and quality of life in advanced lung cancer patients is complex. In the bivariate correlations conducted: pain, dyspnea, anxiety, tiredness, appetite and depression were significantly correlated with all three outcome variables but in the regression analysis, only drowsiness, dyspnea, and appetite predicted fatigue and only depression predicted quality of life. Lastly, the quality of life of participants was significantly associated with the severe fatigue and poor sleep quality reported. Poor sleep quality was the most significant predictor of quality of life. Patients with advanced lung cancer should be screened for sleep disturbance and fatigue when initially diagnosed and those with scores of 3 out of 10 (with 0 being absent and 10 being severe) assessed using comprehensive, valid and reliable assessment tools. Both pharmacological and non-pharmacological evidence-based interventions should be considered to manage poor sleep quality and fatigue in these patients.



Sleep A Very Short Introduction


Sleep A Very Short Introduction
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Author : Steven W. Lockley
language : en
Publisher: OUP Oxford
Release Date : 2012-03-22

Sleep A Very Short Introduction written by Steven W. Lockley and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-22 with Health & Fitness categories.


Why do we need sleep? How much sleep is enough? What is sleep? What happens when we don't get enough? We spend about a third of our lives asleep - it plays a crucial role in our health and wellbeing. References to sleep abound in literature and art, and sleep has been recognized as fundamental to the human condition for thousands of years. Over the past century, our knowledge of how sleep occurs, what it does, and what happens to our health if we do not have enough has developed hugely. The impact of poor sleep on our quality of life is also gaining recognition and the prevalence of sleep disorders in the population appears to be increasing as we live ever stressful lives. This Very Short Introduction addresses the biological and psychological aspects of sleep, providing a basic understanding of what sleep is and how it is measured, looking at sleep through the human lifespan and the causes and consequences of major sleep disorders. Russell G. Foster and Steven W. Lockley go on to consider the impact of modern society, examining the relationship between sleep and work hours, and the impact of our 24/7 society. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.



Behavioural Oncology


Behavioural Oncology
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Author : Marisa Cordella
language : en
Publisher: Springer
Release Date : 2014-07-08

Behavioural Oncology written by Marisa Cordella and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Psychology categories.


Medical, educational, and public health efforts have reduced the spread of many major diseases, yet cancer perseveres, in spite of continuing research and improvements in practice. Especially promising among therapeutic strategies are ones that recognise patients as individuals with thoughts, feelings--and speech. Rooted in deep understanding of the mutual relationship between behavior and cancer, Behavioural Oncology combines extensive clinical wisdom and empirical data to illuminate the psychological, social, and existential aspects of cancer, and to offer a framework for empathic, patient-centered care. Chapters delve into the psychobiology of long-term illness, examining stress, pain, fatigue, sensory and sleep disturbances, and other quality of life issues as well as considerations of age, gender, culture, and comorbidity. The book's emphasis on linguistic and communicative aspects of cancer--and practical skills from respecting patient narratives to delivering bad news--adds necessary depth to concepts of the therapeutic relationship. In this way, the authors warn about overmedicalizing cases to the point of losing patient identity. Major areas of the coverage include: Biology and behavior in cancer prevention and suppression. The psychology of cancer patients: emotions, cognition, and personality Social dimensions, including stigma, coping, and social support Language, communication, and cross-cultural issues Existential, spiritual, and end-of-life concerns Doctor-patient relationships The psychological benefits of complementary therapies Bringing new scope and substance to familiar mind/body constructs, Behavioural Oncology is a definitive reference for a spectrum of healthcare professionals, among them health and clinical psychologists, oncologists and family physicians, oncology nurses, and clinical social workers. Its discussion questions and summaries make it a suitable text for undergraduate and graduate courses in related topics.



The Circadian Clock


The Circadian Clock
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Author : Urs Albrecht
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-23

The Circadian Clock written by Urs Albrecht and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-23 with Science categories.


With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.



Sleep Disorders And Sleep Deprivation


Sleep Disorders And Sleep Deprivation
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2006-10-13

Sleep Disorders And Sleep Deprivation written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-13 with Medical categories.


Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.



Circadian Rhythm Sleep Wake Disorders


Circadian Rhythm Sleep Wake Disorders
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Author : R. Robert Auger
language : en
Publisher: Springer Nature
Release Date : 2020-05-26

Circadian Rhythm Sleep Wake Disorders written by R. Robert Auger and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-26 with Medical categories.


This book resolves to bridge the communication gap between research and clinical practice for circadian rhythm sleep-wake disorders. Beginning with a scientific background on biological timekeeping, opening chapters describe the crucial nature of maintaining delicate temporal organization of physiological and molecular events within the body. Following this are discussions on circadian physiology and methods of circadian assessments. Subsequent chapters then relay comprehensive information regarding the International Classification of Sleep Disorders-defined circadian rhythm sleep-wake disorders (CRSWDs), specifically discussing etiology and epidemiology, but focusing on evidence-based treatment data. Concluding discussions provide guidance for the application of light therapy and discuss future roles for optimized lighting environments. Nuanced and market-demanded, Circadian Rhythm Sleep-Wake Disorders: An Evidence-Based Guide for Clinicians and Investigators is an invaluable resource for Sleep Medicine clinicians, circadian researchers, and other interested parties.