Sleep And Clocks In Aging And Longevity
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Sleep And Clocks In Aging And Longevity
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Author : Anita Jagota
language : en
Publisher: Springer Nature
Release Date : 2023-03-06
Sleep And Clocks In Aging And Longevity written by Anita Jagota and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-06 with Family & Relationships categories.
This edited volume focuses on the interplay between sleep and circadian rhythms with health, aging and longevity. Sleep is absolutely important for human health and survival, as insufficient sleep is associated with a plethora of conditions, including the poor quality of life, onset of several diseases, and premature death. The sleep–wake cycle is an evolutionary conserved neurobiological phenomenon, and is a prominent manifestation of the biological clocks localised in the suprachiasmatic nucleus (SCN). Understanding bidirectional relationship between sleep and circadian rhythms is of utmost importance and urgency, especially in the context of modern lifestyle where sleep is often out of phase with the internal body clocks, social jetlag, artificial lights and so on. The 25 chapters by leading researchers and experts from 11 countries are arranged into seven sections: understanding sleep and clock interlink in health and longevity; sleep, aging and longevity; clock, aging and longevity; melatonin, sleep and clock; genetic regulation of sleep and clock; therapeutic interventions in sleep disorders and clock misalignment; and experimental models to study sleep and clocks in aging and longevity. This book is useful for advanced undergraduate and graduate students, and researchers, educators, and other biomedical professionals.
Circadian Clock And Aging
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Author : Syed Ibrahim Rizvi
language : en
Publisher: Springer Nature
Release Date : 2024-10-15
Circadian Clock And Aging written by Syed Ibrahim Rizvi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-15 with Science categories.
This book aims to understand the inherent circadian cycles of biological processes and their role in maintaining health and healing a variety of diseases. The book is divided into eight sections. The first section introduces circadian rhythms and aging. The second section focuses on the detailed mechanistic approach of oscillatory pathways in mammals. The next section summarizes the sensitivity of the biological clock towards light and the circadian response to melatonin in mammals. The fourth section addresses the circadian architecture at the cellular level and introduces an age-dependent experimental model of rodents for subsequent biochemical and molecular investigations. The subsequent section covers the complexity of circadian regulation in mitochondrial dynamics and its impact on aging. The sixth section of the book discusses the findings obtained from different experimental approaches as a critical threat to the functioning of clock regulatory mechanisms and its associated health consequences during aging in humans and animal models. The circadian oscillatory mechanisms that are dysregulated and might play an important role in the development and progression of neurological disorders such as Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Huntington’s Disease (HD), and Amyotrophic Lateral Sclerosis (ALS), etc are discussed in the next section. Towards the end, the book explores the circadian clock as a possible drug target to restore circadian oscillations.
The Circadian Code
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Author : Satchin Panda, PhD
language : en
Publisher: Rodale Books
Release Date : 2020-02-11
The Circadian Code written by Satchin Panda, PhD and has been published by Rodale Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-11 with Health & Fitness categories.
When we eat may be as important as what we eat. Discover how to align your lifestyle with your body’s natural clock for better overall health—from an award-winning circadian rhythm and aging researcher. “A complete program to recalibrate your day/night activities, optimize sleep, lose weight, learn/work, and exercise.”—Valter Longo, PhD, internationally bestselling author of The Longevity Diet Most people typically wake up, get hungry for meals, and doze off in bed around the same time every day. But if you’ve ever experienced jet lag or pulled an all-nighter, you know that this schedule can easily be thrown off kilter. For some people, that imbalance—difficulty sleeping at night, hunger at odd times, or sudden fatigue at noon—is a constant. Dr. Satchin Panda, one of the leading researchers on circadian rhythms, has a plan to reset your body clock. Beginning with an in-depth explanation of the circadian clock—why it’s important, how it works, and how to know it isn’t working—The Circadian Code outlines lifestyle changes to make to get back on track. It’s a concrete plan to enhance weight loss, improve sleep, optimize exercise, and manage technology so that it doesn’t interfere with your body’s natural rhythm. Dr. Panda’s life-changing methods show you the keys to avoiding and alleviating chronic ailments like diabetes, cancer, and dementia, as well as digestive conditions like acid reflux, heartburn, and irritable bowel disease. In short, knowing your circadian code might just be the secret to turning back the clock and slowing down the aging process.
Hormones In Ageing And Longevity
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Author : Suresh Rattan
language : en
Publisher: Springer
Release Date : 2017-08-19
Hormones In Ageing And Longevity written by Suresh Rattan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-19 with Medical categories.
This multi-chapter book focuses on one of the hottest topics in ageing research – the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity. Hormones are an excellent system of communication between cells and tissues within an organism, and they coordinate a wide range of processes in biological systems, including neuroendocrine and immunological controls. The book offers insights into the latest significant advances in our understanding of the mechanisms of hormonal signaling that control a variety of processes involved in development and ageing. It is divided into four parts: Part I includes a review of the hundred-year history of hormones by the illustrious hormone biochemist Dr. J.R. Tata. Part II presents various chapters on the hormones involved in growth, stress and metabolism, while Part III addresses the hormones controlling cognition and rhythms in ageing processes. Lastly, Part IV discusses the hormones affecting reproduction, immunity and life span. It also explores the use of hormones as pharmaceuticals to maintain health in the elderly. It is a valuable resource for those working in the area of hormone signaling in general and in the field of ageing research in particular.
Longevity And Healthy Aging
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Author : Tzvi Dwolatzky
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-03
Longevity And Healthy Aging written by Tzvi Dwolatzky and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-03 with Medical categories.
Biochemistry And Cell Biology Of Ageing Part V Anti Ageing Interventions
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Author : Viktor I. Korolchuk
language : en
Publisher: Springer Nature
Release Date : 2024-12-18
Biochemistry And Cell Biology Of Ageing Part V Anti Ageing Interventions written by Viktor I. Korolchuk and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-18 with Science categories.
This book provides an up-to-date overview of key areas of ageing research with a special focus on anti-ageing intervention strategies, which are currently very much at the forefront of ageing studies. The volume discusses how dietary restriction, supplements or exercise affect the ageing process. Other intervention strategies reviewed are: chaperone activators, telomerase activation, hormetics, senolytics, NAD boosting, geroprotectors, stem cell therapies, resveratrol and melatonin, to just name a few. This book follows on from Parts I-IV of Biochemistry and Cell Biology of Ageing within the Subcellular Biochemistry book series and highlights anti-ageing intervention strategies that were not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientists alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
Sleep And Aging
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Author : Mark P. Mattson
language : en
Publisher: Elsevier
Release Date : 2005-06-20
Sleep And Aging written by Mark P. Mattson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-20 with Medical categories.
The book describes the mechanisms involved in the maintenance of neuroendocrine-immune interactions in ageing. The lack of this maintenance leads to the appearance of age-related diseases (cancer, infections, dementia) and subsequent disability. The capacity of some hormones or nutritional factors in restoring and remodelling the neuroendocrine-immune response during ageing is reported presenting possible new anti-ageing strategies in order to reach healthy ageing and longevity
Epigenetics Of Aging
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Author : Trygve O. Tollefsbol
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11
Epigenetics Of Aging written by Trygve O. Tollefsbol and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
Circadian Rhythms And Their Impact On Aging
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Author : S. Michal Jazwinski
language : en
Publisher: Springer
Release Date : 2017-10-24
Circadian Rhythms And Their Impact On Aging written by S. Michal Jazwinski and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-24 with Medical categories.
Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book will examine the machinery that constitutes circadian systems and how they impact physiologic processes. It will also discuss how disturbances of circadian rhythms can lead to complex diseases associated with aging. Much of this treatment will focus on metabolism and genome stability. Importantly, the chapters in this book will encompass work in several different models, in addition to human. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.
Role Of Sex And Gender In Aging And Longevity
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Author : Calogero Caruso
language : en
Publisher: Academic Press
Release Date : 2025-08-06
Role Of Sex And Gender In Aging And Longevity written by Calogero Caruso and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-08-06 with Medical categories.
Role of Sex and Gender in Aging and Longevity aims to shed light on the complex interplay between sex and gender differences in the aging process and longevity of individuals. While biological sex differences have long been recognized as influencing various aspects of aging, this book includes how gender also plays a significant role in shaping these processes, accelerating aging, or favoring longevity. By acknowledging the influence of both biological and socially constructed factors, this book offers a comprehensive understanding of why individuals may experience different aging trajectories and have divergent longevity outcomes. This book explores the intricate ways in which gender norms, roles, and expectations shape individual experiences of aging and delves into the social determinants of health that can interact with biological factors to influence the aging process and longevity outcomes. By examining these interactions, this book aims to provide a nuanced understanding of the multifaceted nature of aging and longevity and how sex and gender contribute to these complex phenomena, laying the groundwork for future aging research and providing significant implications for disease prevention, screening, diagnosis, and treatment of age-related conditions.• Explores the distinct significance of sex and gender and their interrelation with aging and longevity• Offers an in-depth overview of the sex- and gender-specific biological and medical aspects of human aging and longevity• Provides the tools required to understand the challenges posed by aging and longevity in individuals and how to approach solving them