Slow Synaptic Responses And Modulation
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Slow Synaptic Responses And Modulation
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Author : K. Kuba
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Slow Synaptic Responses And Modulation written by K. Kuba and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Information flow as nerve impulses in neuronal circuits is regulated at synapses. The synapse is therefore a key element for information processing in the brain. Much attention has been given to fast synaptic transmission, which predominantly regulates impulse-to-impulse transmission. Slow synaptic transmission and modu lation, however, sometimes have been neglected in considering and attempting to understand brain function. Slow synaptic potentials and modulation occur with a considerable delay in response to the accumulation of synaptic and modulatory inputs. In these contexts, they are plastic in nature and play important roles in information processing in the brain. A symposium titled "Slow Synaptic Responses and Modulation" was held as the satellite symposium to the 75th Annual Meeting of the Physiological Society of Japan on March 30-31, 1998, in Kanazawa. The theme was selected not only for the reason mentioned above, but also because of the considerable involvement of many Japanese scholars in establishing the basic issues. Following the dawn of synaptic physiological research, as Sir John Eccles, Sir Bernard Katz, and Professor Stephen Kuffler carried out pioneer work, Professor Kyozou Koketsu and Professor Benjamin Libet, the students of Sir John Eccles, and their colleagues established the concept of slow synaptic responses and modulation by studying vertebrate sympathetic ganglia. Since then, the concept has been ex panded with detailed investigations of both peripheral and central synapses at the levels of single ion channels, intracellular Ca"+ dynamics, intracellular transduc tion mechanisms, and genes.
Neuromodulation Of Executive Circuits
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Author : M. Victoria Puig
language : en
Publisher: Frontiers Media SA
Release Date : 2016-01-21
Neuromodulation Of Executive Circuits written by M. Victoria Puig and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-21 with Clinical neuropsychology categories.
High-order executive tasks involve the interplay between frontal cortex and other cortical and subcortical brain regions. In particular, the frontal cortex, striatum and thalamus interact via parallel fronto-striatal "loops" that are crucial for the executive control of behavior. In all of these brain regions, neuromodulatory inputs (e.g. serotonergic, dopaminergic, cholinergic, adrenergic, and peptidergic afferents) regulate neuronal activity and synaptic transmission to optimize circuit performance for specific cognitive demands. Indeed, dysregulation of neuromodulatory input to fronto-striatal circuits is implicated in a number of neuropsychiatric disorders, such as schizophrenia, depression, and Parkinson's disease. However, despite decades of intense investigation, how neuromodulators influence the activity of fronto-striatal circuits to generate the precise activity patterns required for sophisticated cognitive tasks remains unknown. In part, this reflects the complexity of the cellular microcircuits in these brain regions (i.e. heterogeneity of neuron subtypes and connectivity), cell-type specific expression patterns for the numerous receptor subtypes mediating neuromodulatory signals, and the potential interaction of multiple signaling cascades in individual neurons. This Research Topic includes 10 original research articles and seven review articles addressing the role of neuromodulation in executive function at multiple levels of analysis, ranging from the activity of single voltage-dependent ion channels to computational models of network interactions in cortex-striatum-thalamus systems.
International Review Of Neurobiology
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Author :
language : en
Publisher: Academic Press
Release Date : 1994-10-18
International Review Of Neurobiology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-10-18 with Science categories.
Published since 1959, this serial presents in-depth reviews on key topics in neuroscience, from molecules to behavior. The serial stays keenly attuned to recent developments in the field through the contributions offirst-class experts. Neuroscientists as well as clinicians, psychologists, physiologists, and pharmacologists will find this serial an indispensable addition to their library.
Modulation Of Neuronal Responses
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Author : Giedrius T. Buračas
language : en
Publisher: IOS Press
Release Date : 2003
Modulation Of Neuronal Responses written by Giedrius T. Buračas and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
The Cooperative Neuron
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Author : William A. Phillips
language : en
Publisher: Oxford University Press
Release Date : 2023
The Cooperative Neuron written by William A. Phillips and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Medical categories.
"A new era is dawning in the sciences of mind and brain. This book provides an overview of a conceptual revolution that is occurring in our understanding of the cellular foundations of mental life and its disorders. It relates conscious perception, thought, and action to recently discovered capabilities of a special class of neocortical neuron that has long been known to be widely distributed through the cerebral neocortex. These neurons are called pyramidal cells because their cell bodies have an approximately pyramidal shape. Many, though not all, of those cells are sensitive to context - as this book describes in detail. Though this cellular context-sensitivity involves complex events that are unfamiliar to many neuroscientists and to most psychologists, the conceptual revolution to which these discoveries lead is in essence simple. It is now known that many pyramidal neurons in the neocortex have two functionally distinct sets of input. One set provides the input about which the neuron usually transmits information. The other set can selectively amplify that transmission when it is useful to do so in the context of information being transmitted by other neurons. This form of context-sensitive information processing is cooperative in that it seeks agreement between the active neurons, thus reducing mental conflict"--
Neural Cell Biology
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Author : Cheng Wang
language : en
Publisher: CRC Press
Release Date : 2017-06-26
Neural Cell Biology written by Cheng Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-26 with Medical categories.
This book delineates how systems biology, pharmacogenomic, and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model. The text reviews and discusses approaches that can be used as effective tools to dissect mechanisms underlying pharmacological and toxicological phenomena associated with the exposure to drugs or environmental toxicants during development. The book intends to elaborate functional outcomes of component-to-component relationships using rodent and nonhuman primate in vitro and in vivo models that allow for the directional and quantitative description of the complete organism in response to environmental perturbations. In addition, attention has also been directed to some of the more recent methodologies, including genomics, proteomics and metabolomics, applied in the evolutionary neurobiological field.
Noback S Human Nervous System Seventh Edition
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Author : Norman L. Strominger
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-07
Noback S Human Nervous System Seventh Edition written by Norman L. Strominger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-07 with Science categories.
With this seventh edition, Noback’s Human Nervous System: Structure and Function continues to combine clear prose with exceptional original illustrations that provide a concise lucid depiction of the human nervous system. The book incorporates recent advances in neurobiology and molecular biology. Several chapters have been substantially revised. These include Development and Growth, Blood Circulation and Imaging, Cranial Nerves and Chemical Senses, Auditory and Vestibular Systems, Visual System, and Cerebral Cortex. Topics such as neural regeneration, plasticity and brain imaging are discussed. Each edition of The Human Nervous System has featured a set of outstanding illustrations drawn by premier medical artist Robert J. Demarest. Many of the figures from past editions have been modified and/or enhanced by the addition of color, which provides a more detailed visualization of the nervous system. Highly praised in its earlier versions, this new edition offers medical, dental, allied health science and psychology students a readily understandable and organized view of the bewilderingly complex awe-inspiring human nervous system. Its explanatory power and visual insight make this book an indispensable source of quick understanding that readers will consult gratefully again and again.
Neuroscience And Connectionist Theory
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Author : Mark A. Gluck
language : en
Publisher: Psychology Press
Release Date : 2013-02-01
Neuroscience And Connectionist Theory written by Mark A. Gluck and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-01 with Psychology categories.
Written for cognitive scientists, psychologists, computer scientists, engineers, and neuroscientists, this book provides an accessible overview of how computational network models are being used to model neurobiological phenomena. Each chapter presents a representative example of how biological data and network models interact with the authors' research. The biological phenomena cover network- or circuit-level phenomena in humans and other higher-order vertebrates.
The Metabotropic Glutamate Receptors
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Author : P. Jeffrey Conn
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
The Metabotropic Glutamate Receptors written by P. Jeffrey Conn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
The Metabotropic Glutamate Receptors offers state-of-the-art summaries and reviews of virtually everything known today about metabotropic glutamate receptors (mGluRs), including their molecular biology, pharmacology, anatomical distribution, and physiological and pathological roles. Illuminating the overall role played by this crucial class of receptors in brain function, the book also pinpoints those areas in which there is the greatest continuing need for focused research. Because mGluRs have the potential for participating in virtually all known functions of the central nervous system (CNS), the opportunity now exists to develop pharmacological agents that can potentially alter many brain disease processes by selective interaction with precise CNS functions. With its critical and insightful reviews, The Metabotropic Glutamate Receptors will immediately become your essential key to the development of novel treatment strategies for the widest variety of neurological disorders.
Catecholamine Research
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Author : Toshiharu Nagatsu
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Catecholamine Research written by Toshiharu Nagatsu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
This book is based on invited presentations at the Ninth International Catecholamine Symposiwn. Over several decades, each International Catecholamine Symposiwn (ICS) has provided a uniquely important forwn for updating basic as well as clinical research on the catecholamines, dopamine, norepinephrine, and epinephrine. The first ICS took nd n1 place in Bethesda, Maryland, in the USA in 1958; the 2 in Milan, Italy in 1965; the 3 th in Strasbourg, France in 1973; the 4th in Asilomar, California, USA in 1978; the 5 in th th Goteborg, Sweden in 1983; the 6 in Jerusalem, Israel,in 1987; the 7 in Amsterdam, th Netherlands in 1992; and the 8 in Asilomar, California, USA in 1996. th The 9 International Catecholamine Symposiwn (9ICS) was held in Kyoto, Japan, th March 31-April 5, 2001. This ICS was held concurrently with the 5 International th Conference on Progress in Alzheimer's and Parkinson's Disease (5 ADPD). These international meetings were coordinated to be a joint international congress. Catecholamines and related neurotransmitters and neuromediators play important roles in the pathogenesis of symptoms and neurodegenerative processes of Alzheimer's disease and Parkinson's disease. Therefore, the Joint Congress provided an opportunity for investigators and clinicians working in these fields to exchange their· most recent investigational results and clinical experiences. This Joint International Congress turned out to be an enormous success, attended by 1258 participants from 38 countries, in an enthusiastic and pleasant atmosphere.