Small Peptides
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Small Peptides
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Author : A.S. Dutta
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Small Peptides written by A.S. Dutta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Pharmacochemistry Library, Volume 19: Small Peptides: Chemistry, Biology, and Clinical Studies focuses on the processes, reactions, properties, and characteristics of peptides, including analogues and proteases. The publication first takes a look at angiotensin II and bombesin/gastrin-releasing peptide. Topics include conformationally restricted analogues of bombesin, non-peptide antagonists of angiotensin II, receptor subtypes of angiotensin II, and bombesin/GRP antagonists and cancer. The text then elaborates on bradykinin, cholecystokinin, and enkephalin analogues. The manuscript examines luteinizing hormone releasing hormone and somatostatin. Topics include enzymic degradation of somatostatin and analogues, clinical applications of somatostatin analogues, and pharmacological and clinical studies with LHRH agonists and antagonists. The formulation of peptides and inhibitors of aspartyl proteases are also mentioned. The book is a valuable source of information for chemists, biologists, and readers interested in small peptides.
Chemical Aspects Of The Structure Of Small Peptides
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Author : Dorothy Wrinch
language : en
Publisher:
Release Date : 1960
Chemical Aspects Of The Structure Of Small Peptides written by Dorothy Wrinch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1960 with Science categories.
Sequence Specific Reactivity Of Short Peptides
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Author : Gary L. Juskowiak II
language : en
Publisher: Gary L. Juskowiak II
Release Date : 2009-05-27
Sequence Specific Reactivity Of Short Peptides written by Gary L. Juskowiak II and has been published by Gary L. Juskowiak II this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-27 with Science categories.
Peptide And Peptidomimetic Therapeutics
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Author : Nir Qvit
language : en
Publisher: Academic Press
Release Date : 2022-09-22
Peptide And Peptidomimetic Therapeutics written by Nir Qvit and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-22 with Science categories.
Peptide and Peptidomimetic Therapeutics: From Bench to Beside offers applied, evidence-based instruction on developing and applying peptide therapeutics in disease treatment, driving drug discovery, and improving patient care. Here, researchers, clinicians and students will find tools to harness the full power of peptides and peptidomimetics and improve bioavailability, stability, efficiency and selectivity of new therapeutics and their application in treatment plans. More than 20 leaders in the field share their approaches for identifying and advancing peptide and peptidomimetic therapeutics. Topics examined run from "bench to bedside," beginning with fundamental peptide science, protein-protein interactions and peptide synthesis. Later chapters examine modes for peptide drug delivery, including cell penetration peptide and peptidomimetic delivery, as well as the targeting of specific disease types, peptide therapeutics as applied to infectious disease, cancer, metabolic disorders, neurodegenerative disorders, and skin disorders, and antiparasitic and immunosuppressive peptidomimetics. Helps researchers and clinicians harness the full of power of peptides and peptidomimetics in their daily work and drug discovery Features chapters running from “bench to bedside , providing a thorough grounding in fundamental peptide science, drug delivery methods, and targeting of specific disease types Features chapter contributions from international leaders in peptide science and drug development
Chemical Aspects Of The Structure Of Small Peptides
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Author :
language : en
Publisher:
Release Date : 1960
Chemical Aspects Of The Structure Of Small Peptides written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1960 with Peptides categories.
Inhibitors Of Protein Protein Interactions
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Author : Ali Tavassoli
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-12-07
Inhibitors Of Protein Protein Interactions written by Ali Tavassoli and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-07 with Science categories.
Protein-protein interactions (PPI) are at the heart of the majority of cellular processes, and are frequently dysregulated or usurped in disease. Given this central role, the inhibition of PPIs has been of significant interest as a means of treating a wide variety of diseases. However, there are inherent challenges in developing molecules capable of disrupting the relatively featureless and large interfacial areas involved. Despite this, there have been a number of successes in this field in recent years using both traditional drug discovery approaches and innovative, interdisciplinary strategies using novel chemical scaffolds. This book comprehensively covers the various aspects of PPI inhibition, encompassing small molecules, peptidomimetics, cyclic peptides, stapled peptides and macrocycles. Illustrated throughout with successful case studies, this book provides a holistic, cutting-edge view of the subject area and is ideal for chemical biologists and medicinal chemists interested in developing PPI inhibitors.
Implantable Technologies
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Author : Ved Srivastava
language : en
Publisher: Royal Society of Chemistry
Release Date : 2021-10-20
Implantable Technologies written by Ved Srivastava and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-20 with Science categories.
Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance. Significant progress has been made in various alternative implantable delivery technologies, notably in intraocular and subcutaneous devices. Despite success in research and clinical studies, long-term clinical efficacy may be more limited and different aspects related to drug development and commercialization using these technologies are not well understood or practiced in the commercial setting. This book provides a comprehensive and cohesive picture of the latest in the field while also outlining the opportunities and challenges in implantable technology. Implantable Technologies: Pepties and Biologic Drug Development is an ideal reference for any postgraduate or researcher interested in utilising implantable technologies and novel routes of drug administration. The book will also be of interest to those involved in formulation and clinical application for a wide array of disease areas in addition to more established paradigms such as diabetes and pain management.
The Peptides Analysis Synthesis Biology
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Author : Erhard Gross
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Peptides Analysis Synthesis Biology written by Erhard Gross and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
The Peptides: Analysis, Synthesis, Biology: Volume 4: Modern Techniques of Conformational, Structural, and Configurational Analysis is an open-ended treatise that provides comprehensive and critical reviews of important developments in all areas of peptide research including analysis, synthesis, and biology. X-ray structure studies, amino acid analysis, and chiroptical analysis of configuration are discussed, along with solid-phase sequencing and ultramicroanalysis with the aid of fluorescence. This volume is comprised of six chapters and begins with an account of crystal structure analysis on molecules containing 2-12 peptide units, focusing on the variety of intramolecular hydrogen bonds, cis peptide units, and multiple conformation. Conformational changes upon complexation with metal ions are considered, together with the inclusion of solvents as integral parts of a molecular structure. The following chapters explore the conformations of insulin, glucagon, pancreatic polypeptide and related molecules, as well as the molecular biology of these hormones based on crystal structures; the usefulness of chiroptical techniques for determining the absolute configuration of amino acids and small peptides; and ultramicroanalysis of peptides and proteins by high performance liquid chromatography and fluorescence detection. The final chapter looks at the status and future potential of solid-phase sequencing. This book is intended as a reference for specialists, a guide for the novice, and a forum for investigators concerned with research on peptides and proteins.
The Interactions Of Small Peptides And Polyhistidine With Phospholipid Bilayers Studied By Solution Phase Nmr Spectroscopy
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Author : Rachelle Harley Thompson
language : en
Publisher:
Release Date : 2000
The Interactions Of Small Peptides And Polyhistidine With Phospholipid Bilayers Studied By Solution Phase Nmr Spectroscopy written by Rachelle Harley Thompson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.
Peptides From A To Z
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Author : Hans-Dieter Jakubke
language : en
Publisher: John Wiley & Sons
Release Date : 2008-09-08
Peptides From A To Z written by Hans-Dieter Jakubke and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-08 with Science categories.
This mini-encyclopedia contains more than 1,500 alphabetical entries from the entire field of peptide science in one handy volume, as well as the technical terms, acronyms and concepts used in peptide chemistry. It also features the complete sequence of more than 800 peptides, numerous illustrations and numerous cross-references. Areas covered include: - biological peptides and small proteins - peptide hormones - pharmaceutical peptides - peptide antibiotics - peptide inhibitors - peptide reagents - peptide tags - structural classes - synthesis and purification - analytical methods - proteomics and peptidomics. Condensed yet accessible, only essential information is displayed, extensively linked via references to the recent scientific literature for further study.