Solid Phase Organic Syntheses Volume 1

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Solid Phase Organic Syntheses Volume 1

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Author : Anthony W. Czarnik
language : en
Publisher: John Wiley & Sons
Release Date : 2004-04-07

Solid Phase Organic Syntheses Volume 1 written by Anthony W. Czarnik and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-07 with Science categories.

The rapid expansion of combinatorial chemistry has renewed interest in solid-phase organic synthesis, a method that lends itself well to creating and screening large numbers of lead compounds. Solid-Phase Organic Syntheses, Volume 1 is the first volume in a series that will be updated annually, filling a gap in the existing chemical literature. Providing information previously unavailable from a single resource, this series is dedicated to providing researchers in the field with validated and tested methods for the solid-phase synthesis of interesting and biologically relevant molecules. Solid-phase methods will virtually always be invented for application in combinatorial organic synthesis. To meet these specific needs, Solid-Phase Organic Syntheses, Volume 1 focuses on a single type of synthetic transformation accomplished on solid support, and indicates how procedures are optimized to work with a structurally-wide variety of reagents. Written by recognized leaders in the field who review and test all chemical protocols before publication, organic transformations are organized by type of compound synthesized and reaction type. For the first time, experimental details for proven solid-phase synthetic molecules are collected in a single, invaluable resource. Solid-Phase Organic Syntheses, Volume 1 provides combinatorial chemists and researchers in organic chemistry and medicinal chemistry with the tools and descriptive protocols to achieve syntheses of desired compounds using a variety of solid supports and reagents.

Side Reactions In Organic Synthesis

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Author : Florencio Zaragoza Dörwald
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06

Side Reactions In Organic Synthesis written by Florencio Zaragoza Dörwald and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.

Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates

Combinatorial Chemistry

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Author : Stephen R. Wilson
language : en
Publisher: John Wiley & Sons
Release Date : 1997-03-28

Combinatorial Chemistry written by Stephen R. Wilson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-03-28 with Medical categories.

The new time-saving revolution in drug discovery. Combinatorial chemistry, a method for synthesizing millions of chemical compounds much faster than usual, is becoming one of the most useful technical tools available to chemists and researchers working today. Using current advances in computer and laboratory techniques, combinatorial chemistry has freed professionals from the drudgery of piecemeal experimental work and opened new creative possibilities for experimentation. Combinatorial Chemistry: Synthesis and Application details critical aspects of the technique, featuring the work of some of the world's leading chemists, many of whom played a key role in its development. Including examples of both solution-phase and solid-phase approaches as well as the full complement of organic chemistry technologies currently available, the book describes: * Concepts and terms of combinatorial chemistry * Polymer-supported synthesis of organic compounds * Macro beads as microreactors * Solid-phase methods in combinatorial chemistry * Encoded combinatorial libraries, including Rf-encoding of synthesis beads * Strategies for combinatorial libraries of oligosaccharides * Combinatorial libraries of peptides, proteins, and antibodies using biological systems. While combinatorial chemistry originated in peptide chemistry, this volume has deliberately focused on nonpeptide organic applications, illustrating the technique's wide uses. Combinatorial Chemistry introduces organic, medicinal, and pharmaceutical chemists as well as biochemists to this exciting, cost-effective, and practical technique, which has unlocked creative potential for the next millennium.

Solid Phase Organic Syntheses

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Author : Anthony W. Czarnik
language : en
Publisher:
Release Date : 2001

Solid Phase Organic Syntheses written by Anthony W. Czarnik and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.

Advances In Organic Synthesis

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Author : Atta -ur- Rahman
language : en
Publisher: Bentham Science Publishers
Release Date : 2017-09-07

Advances In Organic Synthesis written by Atta -ur- Rahman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-07 with Science categories.

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field. Advances in Organic Synthesis is essential for all organic chemists in the academia and industry who wish to keep abreast of rapid and important developments in the field.

Domino Reactions In Organic Synthesis

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Author : Lutz F. Tietze
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-13

Domino Reactions In Organic Synthesis written by Lutz F. Tietze and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Science categories.

Domino reactions enable you to build complex structures in one-pot reactions without the need to isolate intermediates- a dream comes true. In this book, the well-respected expert, Professor Lutz Tietze, summarizes the possibilities of this reaction type - an approach for an efficiant, economically benificial and ecological benign synthesis. A definite must for every organic chemist.

Comprehensive Organic Synthesis

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Author :
language : en
Publisher: Newnes
Release Date : 2014-02-14

Comprehensive Organic Synthesis written by and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-14 with Science categories.

The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively

Lanthanides Chemistry And Use In Organic Synthesis

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Author : Reiner Anwander
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-03-08

Lanthanides Chemistry And Use In Organic Synthesis written by Reiner Anwander and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-03-08 with Medical categories.

The use of lanthanides in organic chemistry and in organic synthesis has attracted broad interest recently because of the unique reactivities and selectivities exhibited by compounds of these rare earth elements. In particular, several major advances have been made in the last five years. This volume of Topics in Organometallic Chemistry is designed to provide the specialist and non-specialist alike with a much needed overview of recent developments. Contributions by leaders in the field focus on stereoselective organic synthesis using lanthanides, the principles of lanthanide chemistry, lanthanide-based chiral catalysts, low-valent lanthanide compounds, polymer synthesis using lanthanide catalysts, and polymer-supported lanthanide catalysts used in organic synthesis.

Microwave Assisted Organic Synthesis

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Author : D. Bogdal
language : en
Publisher: Elsevier
Release Date : 2006-01-04

Microwave Assisted Organic Synthesis written by D. Bogdal and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-04 with Science categories.

Microwave-assisted Organic Synthesis: One Hundred Reaction Procedures provides readers with a broad overview of microwave assisted Organic Synthesis, enabling students and researchers alike to produce more efficient and high yield syntheses while saving time and resources. The work addresses key problems faced by chemistry laboratories in academia and in industry, that of an ever increasing need for procedures which are low-waste, energy efficient, high yield, occur over a short reaction period, and use environmentally friendly solvents. All these factors play an important role in the development of Green Chemistry methods, and in this, Microwave-assisted Organic Synthesis: One Hundred Reaction Procedures is an excellent resource for any library. - Provides a broad overview of microwave enhanced chemistry - Extensive references to the source of each procedure, including equipment used, full operating procedure, and associated hazards - Includes exercises and worked problems which can support more independent study

Handbook On Synthesis Strategies For Advanced Materials

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Author : A. K. Tyagi
language : en
Publisher: Springer Nature
Release Date : 2021-08-17

Handbook On Synthesis Strategies For Advanced Materials written by A. K. Tyagi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-17 with Technology & Engineering categories.

This book presents state-of-the-art coverage of synthesis of advanced functional materials. Unconventional synthetic routes play an important role in the synthesis of advanced materials as many new materials are metastable and cannot be synthesized by conventional methods. This book presents various synthesis methods such as conventional solid-state method, combustion method, a range of soft chemical methods, template synthesis, molecular precursor method, microwave synthesis, sono-chemical method and high-pressure synthesis. It provides a comprehensive overview of synthesis methods and covers a variety of materials, including ceramics, films, glass, carbon-based, and metallic materials. Many techniques for processing and surface functionalization are also discussed. Several engineering aspects of materials synthesis are also included. The contents of this book are useful for researchers and professionals working in the areas of materials and chemistry.