Somatic Genome Manipulation
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Somatic Genome Manipulation
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Author : Xiu-Qing Li
language : en
Publisher: Springer
Release Date : 2015-05-15
Somatic Genome Manipulation written by Xiu-Qing Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-15 with Science categories.
Somatic genome manipulation is required when a sexual crossing approach cannot be used in breeding or genetic treatment of an individual organism. Examples can include gene- or cell-therapy of a person to correct disease, genetic improvement of vegetatively propagated plants, and genetic replacement of cytoplasm without significantly modifying the nuclear genome. The advantage of somatic genome manipulation is maintenance of the general genotype while correcting one or more traits. Somatic genome manipulation is also an option for genetic improvement of sexually propagated plants in polyploidy breeding or in overcoming issues of sexual incompatibility. Recent novel technologies in somatic genome manipulation are developing quickly but much of this literature is fragmented and difficult or inconvenient to access. This book represents the first attempt to assemble updated reviews, detailed protocols, and their applications in all fields in which somatic genome manipulation has thrived. This is a truely one-of-a-kind work that brings together the most important and relevant advances in somatic genome manipulation in plants, algae, microorganisms, humans and animals, and demonstrates where the science interacts and where it diverges. The chapters are written by experts on the topic with ready-to-use protocols that were originally developed or adapted from the literature in their laboratories. We expect that this book will be useful for students, researchers, and teachers in both plant and animal research as a resource for the latest information on somatic genome manipulation and for its useful laboratory methods.
Human Genome Editing
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-08-13
Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-13 with Medical categories.
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Somatic Gene Therapy
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Author : P.L. Chang
language : en
Publisher: CRC Press
Release Date : 2018-01-17
Somatic Gene Therapy written by P.L. Chang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-17 with Science categories.
As human gene therapy becomes a clinical reality, a new era in medicine dawns. Novel and innovative developments in molecular genetics now provide opportunities to treat the genetic bases of diseases often untreatable before. Somatic Gene Therapy documents these historical clinical trials, reviews current advances in the field, evaluates the use of the many different cell types and organs amenable to gene transfer, and examines the prospects of various exciting strategies for gene therapy.
Heritable Human Genome Editing
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Author : The Royal Society
language : en
Publisher: National Academies Press
Release Date : 2021-01-16
Heritable Human Genome Editing written by The Royal Society and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-16 with Medical categories.
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Transgenic Modification Of Germline And Somatic Cells
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Author : R.B. Flavell
language : en
Publisher: Springer
Release Date : 1993-11-30
Transgenic Modification Of Germline And Somatic Cells written by R.B. Flavell and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-30 with Medical categories.
Resulting from the Royal Society Discussion Meeting held in July 1992, this volume provides insights into how transgenes are being exploited to discover new knowledge in animals and plants. Overview chapters assess the current understanding of genetic modification and their application in both plants and animals. Topics reviewed include progress in genome mapping; sex determination and embryo formation; epigenetic variation; gene switches and control of development; stem cell manipulation; genetic enhancement of organisms by gene insertion; and disease investigation. Annotation copyright by Book News, Inc., Portland, OR
Human Germline Modification And The Right To Science
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Author : Andrea Boggio
language : en
Publisher: Cambridge University Press
Release Date : 2020-01-09
Human Germline Modification And The Right To Science written by Andrea Boggio and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-09 with Law categories.
A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.
Genetic Manipulation In Crops
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Author : International Rice Research Institute
language : en
Publisher: Int. Rice Res. Inst.
Release Date : 1988
Genetic Manipulation In Crops written by International Rice Research Institute and has been published by Int. Rice Res. Inst. this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Technology & Engineering categories.
Special lectures; Haploid; Mutation, Mutagenesis; Somaclonal variation; Somatic morphogenesis; Protoplasts; Molecular biology of plant gene and genetic manipulation.
Safety Of Genetically Engineered Foods
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2004-07-08
Safety Of Genetically Engineered Foods written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-08 with Science categories.
Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Advances In Gene Technology Molecular Genetics Of Plants And Animals
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Author : Kathleen Downey
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Advances In Gene Technology Molecular Genetics Of Plants And Animals written by Kathleen Downey and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Advances in Gene Technology: Molecular Genetics of Plants and Animals contains the proceedings of the Miami Winter Symposium held in January 1983 in Miami, Florida. The papers explore advances in the molecular genetics of plants and animals and cover a wide range of topics such as genetic manipulation of plants; plant cell cultures, regeneration, and somatic cell fusion; and nitrogen fixation. Practical applications of gene technology with plants are also discussed. Comprised of 84 chapters, this volume begins with an overview of how plants manufacture from carbon dioxide and water all of their substances, paying particular attention to the path of carbon in photosynthesis. The organization of the plant genome is then considered, along with techniques for cell culture, regeneration, and somatic cell fusion; vector systems; and nitrogen fixation. Some chapters focus on gene transfer by protoplast fusion; somatic cell genetic systems in corn; regulation of transcription of the nitrogen fixation operons; and leghemoglobin and nodulin genes of soybean. The final section is devoted to practical applications of gene technology to plants and to technology frontiers in animal biology, in particular embryonic development and vaccines and diagnostic methods for animal diseases. This book should be of value to molecular geneticists.
Genetic Manipulation
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Author : Werner Arber (Microbiologist)
language : en
Publisher: Cambridge University Press
Release Date : 1984-03
Genetic Manipulation written by Werner Arber (Microbiologist) and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984-03 with Science categories.
Twenty-three papers by the Committee on Genetic Experimentation (COGENE) review recent advances in experimental studies on microorganisms, plants and animals.