Spherical Crystallization As A New Platform For Particle Design Engineering
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Spherical Crystallization As A New Platform For Particle Design Engineering
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Author : Yoshiaki Kawashima
language : en
Publisher: Springer
Release Date : 2019-05-21
Spherical Crystallization As A New Platform For Particle Design Engineering written by Yoshiaki Kawashima and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-21 with Medical categories.
This book describes the principles and applications of the spherical crystallization technique, from the standpoint of its inventor. After an introduction on the history of particle design engineering and nanotechnology, the concept of spherical crystallization itself is clearly explained. Attention then turns to the application of spherical crystallization in pharmaceutical processes. It is explained how the technique can provide physicochemical properties suitable for direct tableting of active pharmaceutical ingredients and how it has enabled the development of a novel particulate design platform from single to complex system. Subsequent chapters describe the roles of polymeric spherical crystallization in the preparation of novel microspheres, microballoons for drug delivery systems (DDS) and the development of biocompatible and biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanospheres. The various applications of PLGA nanospheres composite within oral-, pulmonary-, transdermal DDS and cosmetics are fully discussed. Finally, future perspectives are presented on use of the technology in the design and industrial-scale manufacture of new drug delivery systems, highlighting how a continuous pharmaceutical process that meets US Food and Drug Administration quality requirements should soon be introduced.
Smart Technologies In Urban Engineering
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Author : Olga Arsenyeva
language : en
Publisher: Springer Nature
Release Date : 2023-12-18
Smart Technologies In Urban Engineering written by Olga Arsenyeva and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-18 with Technology & Engineering categories.
This book offers a comprehensive review of smart technologies and provides perspectives on their applications in urban engineering. It covers a wide range of applications, from manufacturing engineering and transport logistics to information and computation technologies, providing readers with fresh ideas for future research and collaborations. The book showcases selected papers from the International Conference on Smart Technologies in Urban Engineering (STUE-2023), hosted by O.M. Beketov National University of Urban Economy in Kharkiv, Ukraine. The conference, held on June 8–10, 2023, aimed to address the complex rehabilitation of areas damaged by military conflicts and natural disasters. The contributions within this book offer a wealth of valuable information, fostering a meaningful exchange of experiences among scientists in the field of urban engineering. By delving into this book, readers explore innovative approaches to tackle urban challenges, gain insights from experts, and contribute to the advancement of smart technologies for the betterment of cities worldwide.
Design And Processing Of Particulate Products
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Author : Jim Litster
language : en
Publisher: Cambridge University Press
Release Date : 2016-10-20
Design And Processing Of Particulate Products written by Jim Litster and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-20 with Technology & Engineering categories.
With this unique and comprehensive text, readers will gain the quantitative tools needed to engineer the particulate processes and products that are ubiquitous in modern life. Covering a series of particle and particulate delivery form design processes, with emphasis on design and operation to control particle attributes, and supported by many worked examples, it is essential reading for students and practitioners. Topics covered include a range of particle design processes such as crystallization and precipitation, granulation, grinding, aerosol processes and spray drying, as well as forms of delivery such as granules, tablets, dry powders, and aerosols. Readers will learn from real-world examples how the primary particle properties and the structure and properties of the delivery form can lead to high performance products, ranging from pharmaceuticals, consumer goods and foods, to specialty chemicals, paints, agricultural chemicals and minerals.
Continuous Manufacturing Of Pharmaceuticals
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Author : Peter Kleinebudde
language : en
Publisher: John Wiley & Sons
Release Date : 2017-07-14
Continuous Manufacturing Of Pharmaceuticals written by Peter Kleinebudde and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-14 with Science categories.
A comprehensive look at existing technologies and processes for continuous manufacturing of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical industry has come under intense pressure to improve the efficiency of its manufacturing processes. Continuous process manufacturing provides a proven solution. Among its many benefits are: minimized waste, energy consumption, and raw material use; the accelerated introduction of new drugs; the use of smaller production facilities with lower building and capital costs; the ability to monitor drug quality on a continuous basis; and enhanced process reliability and flexibility. Continuous Manufacturing of Pharmaceuticals prepares professionals to take advantage of that exciting new approach to improving drug manufacturing efficiency. This book covers key aspects of the continuous manufacturing of pharmaceuticals. The first part provides an overview of key chemical engineering principles and the current regulatory environment. The second covers existing technologies for manufacturing both small-molecule-based products and protein/peptide products. The following section is devoted to process analytical tools for continuously operating manufacturing environments. The final two sections treat the integration of several individual parts of processing into fully operating continuous process systems and summarize state-of-art approaches for innovative new manufacturing principles. Brings together the essential know-how for anyone working in drug manufacturing, as well as chemical, food, and pharmaceutical scientists working on continuous processing Covers chemical engineering principles, regulatory aspects, primary and secondary manufacturing, process analytical technology and quality-by-design Contains contributions from researchers in leading pharmaceutical companies, the FDA, and academic institutions Offers an extremely well-informed look at the most promising future approaches to continuous manufacturing of innovative pharmaceutical products Timely, comprehensive, and authoritative, Continuous Manufacturing of Pharmaceuticals is an important professional resource for researchers in industry and academe working in the fields of pharmaceuticals development and manufacturing.
Crystallization Process Systems
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Author : Alan G. Jones
language : en
Publisher: Butterworth-Heinemann
Release Date : 2002-04-24
Crystallization Process Systems written by Alan G. Jones and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-24 with Science categories.
Particulate Crystal Characteristics; Fluid-particle Transport Processes; Crystallization Principles and Techniques; Crystal Formation Processes; Crystallizer Design and Operation; Solid-Liquid Separation Processes; Design of Crystallization Process Systems.
Spherical Nucleic Acids
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Author : Chad A. Mirkin
language : en
Publisher: CRC Press
Release Date : 2021-10-14
Spherical Nucleic Acids written by Chad A. Mirkin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-14 with Science categories.
Spherical nucleic acids (SNAs) comprise a nanoparticle core, and a densely packed and highly oriented nucleic acid shell. They have novel structure-dependent properties that differ from those of linear nucleic acids and that makes them useful in chemistry, biology, the life sciences, medicine, materials science, and engineering. This book is a reprint volume that compiles 101 key papers that have been published by the Mirkin Group at Northwestern University, USA, and their collaborators over the past more than two decades. Volume 1 provides an overview and a historical framework of SNAs and discusses their enabling features, which set them apart from all other forms of matter. Volume 2 covers the general design rules for colloidal crystal engineering with DNA, spanning the building blocks and DNA- and RNA-based "programmable bonds" that can be utilized in preparing such structures. Volume 3 continues the discussion of colloidal crystallization processes and routes to hierarchical assembly, featuring dynamic nanoparticle superlattices and lattices prepared on surfaces or via templating strategies, and explores what one can uniquely learn from and do with colloidal crystals prepared from nucleic acid–functionalized nanomaterials in optics, plasmonics, and catalysis. Volume 4 covers the role of SNAs in biomedicine, especially as diagnostic probes both inside and outside of cells, and treatments based on gene regulation and immunotherapy.
Chemical Engineering Progress
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Author :
language : en
Publisher:
Release Date : 2007
Chemical Engineering Progress written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Chemical engineering categories.
Crystallization Processes
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Author : H. Ohtaki
language : en
Publisher: John Wiley & Sons
Release Date : 1998
Crystallization Processes written by H. Ohtaki and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Science categories.
An overview of crystallization processes of organic and inorganic substances from various homogeneous liquids. Crystal structures, phase transitions and crystallization rates are described in the book in connection with the structure of ions, complexes and molecules of the solution phase.
Controlled Pulmonary Drug Delivery
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Author : Hugh D.C. Smyth
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-24
Controlled Pulmonary Drug Delivery written by Hugh D.C. Smyth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-24 with Medical categories.
The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.
Materials Science And Engineering Laboratory
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Author :
language : en
Publisher:
Release Date : 1993
Materials Science And Engineering Laboratory written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Materials science categories.