Spontaneous And Virus Induced Transformation In Cell Culture


Spontaneous And Virus Induced Transformation In Cell Culture
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Spontaneous And Virus Induced Transformation In Cell Culture


Spontaneous And Virus Induced Transformation In Cell Culture
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Author : Jan Ponten
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Spontaneous And Virus Induced Transformation In Cell Culture written by Jan Ponten and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


A. Definitions of Transformation in vitro When normal tissues or organs are explanted to conditions favoring the growth of cells as individual units ("cell culture"), the original cell population undergoes a large variety of modifications. Only a minority of the cells will thrive and multiply and within a rather short period of time, the complex composition of the original explant is replaced by a much simplified one of only a few recogniz ably different cell types. With most organs fibroblast-like cells survive longest and outgrow other types. This is then a stable state of affairs for many gener ations. This treatise will not discuss whether this simplification and stabilization represents selection of certain pre-existing cell types or a modification of cells into only a few recognizably different categories; for an excellent review see HARRIS. (1964). Table 1. Terminology Employed to Describe Transformations in vitro Type of transformation Essential features Irregular growth Lack of contact inhibition of cell membrane movement ("ruffled membranes") between juxtaposed cells Unrestrained growth Deficient inhibition of the cell cycle (mitosis) in a crowded culture Infinite growth Capacity of cells to undergo an infinite number of di visions (formation of established cell lines) Cells may depart from this typical behavior in numerous ways involving for instance cellular morphology, immunology, chromosomes or metabolism. Such changes have, sometimes rather vaguely, been called "transformations". This is unprecise and the term "transformation" will here be used exclusively to indicate disturbances in cell growth related to neoplasia.



Spontaneous And Virus Induced Transformation In Cell Culture


Spontaneous And Virus Induced Transformation In Cell Culture
DOWNLOAD
FREE 30 Days

Author : Jan Pontén
language : en
Publisher: Springer
Release Date : 1971

Spontaneous And Virus Induced Transformation In Cell Culture written by Jan Pontén and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Cell culture categories.


When normal tissues or organs are explanted to conditions favoring the growth of cells as individual units (cell culture) the original cell population undergoes a large variety of modification. Only a minory of the cells with thrive and multiply and within a rather short period of time, the complex composition of the original explant is replaced by a much simplified one and only a few recognizably different cell types.



Cumulated Index Medicus


Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1985

Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Medicine categories.




Journal Of The National Cancer Institute


Journal Of The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 1980

Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Cancer categories.




Carcinogenesis Abstracts


Carcinogenesis Abstracts
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Author :
language : en
Publisher:
Release Date : 1977

Carcinogenesis Abstracts written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Carcinogenesis categories.




Partial Bibliography On Type B And Type C Viruses In Relation To Animal Neoplasia Covering Period Of Jan 1967 Through Dec 1970


Partial Bibliography On Type B And Type C Viruses In Relation To Animal Neoplasia Covering Period Of Jan 1967 Through Dec 1970
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FREE 30 Days

Author : National Cancer Institute (U.S.)
language : en
Publisher:
Release Date : 1971

Partial Bibliography On Type B And Type C Viruses In Relation To Animal Neoplasia Covering Period Of Jan 1967 Through Dec 1970 written by National Cancer Institute (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with categories.




International Review Of Cytology


International Review Of Cytology
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Author :
language : en
Publisher: Academic Press
Release Date : 1965-01-01

International Review Of Cytology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1965-01-01 with Science categories.


International Review of Cytology



Partial Bibliography On Type B And Type C Viruses In Relation To Animal Neoplasia Covering Period Of January 1967 Through December 1970


Partial Bibliography On Type B And Type C Viruses In Relation To Animal Neoplasia Covering Period Of January 1967 Through December 1970
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FREE 30 Days

Author : National Cancer Institute (U.S.). Program Analysis and Communication Section. Information Unit
language : en
Publisher:
Release Date : 1971

Partial Bibliography On Type B And Type C Viruses In Relation To Animal Neoplasia Covering Period Of January 1967 Through December 1970 written by National Cancer Institute (U.S.). Program Analysis and Communication Section. Information Unit and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Oncogenic viruses categories.




Journal


Journal
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FREE 30 Days

Author : National Cancer Institute (U.S.)
language : en
Publisher:
Release Date : 1966

Journal written by National Cancer Institute (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1966 with Cancer categories.




The Epstein Barr Virus


The Epstein Barr Virus
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Author : M. A. Epstein
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Epstein Barr Virus written by M. A. Epstein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.