Statistical Analysis Of Proteomics Metabolomics And Lipidomics Data Using Mass Spectrometry
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Statistical Analysis Of Proteomics Metabolomics And Lipidomics Data Using Mass Spectrometry
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Author : Susmita Datta
language : en
Publisher: Springer
Release Date : 2016-12-15
Statistical Analysis Of Proteomics Metabolomics And Lipidomics Data Using Mass Spectrometry written by Susmita Datta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-15 with Medical categories.
This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies. Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types—as opposed to the familiar data structures in more classical genomics—but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.
Omics Based Approaches In Plant Biotechnology
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Author : Rintu Banerjee
language : en
Publisher: John Wiley & Sons
Release Date : 2019-02-28
Omics Based Approaches In Plant Biotechnology written by Rintu Banerjee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-28 with Technology & Engineering categories.
Burgeoning world population, decreased water supply and land resources, coupled with climate change, result in severe stress conditions and a great threat to the global food supply. To meet these challenges, exploring Omics Technologies could lead to improved yields of cereals, tubers and grasses that may ensure food security. Improvement of yields through crop improvement and biotechnological means are the need-of-the-hour, and the current book “OMICS-Based Approaches in Plant Biotechnology”, reviews the advanced concepts on breeding strategies, OMICS technologies (genomics, transcriptomics and metabolomics) and bioinformatics that help to glean the potential candidate genes/molecules to address unsolved problems related to plant and agricultural crops. The first six chapters of the book are focused on genomics and cover sequencing, functional genomics with examples on insecticide resistant genes, mutation breeding and miRNA technologies. Recent advances in metabolomics studies are elucidated in the next 3 chapters followed by 5 chapters on bioinformatics and advanced techniques in plant biotechnology and crop breeding. The information contained in the volume will help plant breeders, plant biotechnologists, plant biochemists, agriculture scientists and researchers in using this applied research to focus on better crop breeding and stress adaptation strategies.
Processing Metabolomics And Proteomics Data With Open Software
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Author : Robert Winkler
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-03-16
Processing Metabolomics And Proteomics Data With Open Software written by Robert Winkler and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-16 with Science categories.
Metabolomics and proteomics allow deep insights into the chemistry and physiology of biological systems. This book expounds open-source programs, platforms and programming tools for analysing metabolomics and proteomics mass spectrometry data. In contrast to commercial software, open-source software is created by the academic community, which facilitates the direct interaction between users and developers and accelerates the implementation of new concepts and ideas. The first section of the book covers the basics of mass spectrometry, experimental strategies, data operations, the open-source philosophy, metabolomics, proteomics and statistics/ data mining. In the second section, active programmers and users describe available software packages. Included tutorials, datasets and code examples can be used for training and for building custom workflows. Finally, every reader is invited to participate in the open science movement.
Mass Spectrometry
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Author : Anshul Pandey
language : en
Publisher: Educohack Press
Release Date : 2025-02-20
Mass Spectrometry written by Anshul Pandey and has been published by Educohack Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-20 with Science categories.
"Mass Spectrometry: Techniques and Applications" is a comprehensive guide to understanding and mastering the principles, techniques, and applications of this powerful analytical method. We cover a wide range of topics, delving into the intricacies of ionization methods, mass analyzers, ion detection, and data analysis strategies crucial for accurate and reliable mass spectrometry results. We explore the fundamentals of mass spectrometry, including ionization and fragmentation principles, isotopic patterns, and mass-to-charge ratio calculations. Various ionization techniques such as electrospray ionization (ESI), matrix-assisted laser desorption/ionization (MALDI), and electron ionization (EI) are elucidated, providing insights into their mechanisms and applications. Advanced topics like tandem mass spectrometry (MS/MS), high-resolution mass spectrometry (HRMS), and ion mobility spectrometry (IMS) are also covered, offering a comprehensive understanding of cutting-edge techniques and instrumentation. Practical aspects of mass spectrometry, including method development, calibration strategies, data interpretation, and troubleshooting, are detailed to help researchers, students, and professionals navigate experiments effectively. Additionally, we showcase the diverse applications of mass spectrometry across fields such as pharmaceuticals, environmental analysis, metabolomics, proteomics, forensics, and materials science. Case studies, real-world examples, and emerging trends provide valuable insights into the role of mass spectrometry in advancing scientific discovery and addressing societal challenges. With clear explanations, illustrative diagrams, and practical tips, "Mass Spectrometry: Techniques and Applications" serves as an indispensable resource for anyone seeking a comprehensive and up-to-date reference on this essential analytical technique.
Reviews In Pharmaceutical And Biomedical Analysis
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Author : Paraskevas D. Tzanavaras
language : en
Publisher: Bentham Science Publishers
Release Date : 2010
Reviews In Pharmaceutical And Biomedical Analysis written by Paraskevas D. Tzanavaras and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Science categories.
"Reviews in Pharmaceutical and Biomedical Analysis contains coverage and review of new trends and applications in all areas of pharmaceutical, biomedical and analytical chemistry. Authors have contributed review articles according to their expertise on var"
High Throughput Plant Metabolomics
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Author : Jen-Tsung Chen
language : en
Publisher: CABI
Release Date : 2025-06-27
High Throughput Plant Metabolomics written by Jen-Tsung Chen and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-27 with Technology & Engineering categories.
This book summarizes the current achievements of metabolomics in revealing the roles of primary and secondary metabolisms of plants both used as major crops and for the production of medicines. It presents methods and applications of metabolomics for the exploration of stress responses, which may pave the way for obtaining climate-smart and stress-tolerant crops able to face biotic and abiotic stressors in a globally-changing climate. These technologies can advance the exploration of plant physiology as well as precision crop breeding for future anti-stress, high-quality, and high-yield plants and in doing so can achieve sustainable agriculture and therefore support the Sustainable Development Goals, the Paris Agreement, and the vision of sustainable agriculture. This book is an ideal reference for students, researchers, teachers, professors, and experts in the field of plant science and crop breeding. It provides an effective overview of the critical topic of plant science and will help to inspire and assist researchers as they design new experiments and methods.
Cutting Edge Diagnostic Technologies In Cardiovascular Diseases
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Author : Haipeng Liu
language : en
Publisher: CRC Press
Release Date : 2025-06-23
Cutting Edge Diagnostic Technologies In Cardiovascular Diseases written by Haipeng Liu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-23 with Technology & Engineering categories.
This book provides a comprehensive overview of cutting-edge technologies in the diagnosis of multiple cardiovascular disease. Readers will understand technical advancements and research gaps, which will help them to optimize the design of algorithms and devices. Cutting-Edge Diagnostic Technologies in Cardiovascular Diseases: Towards Data-Driven Smart Healthcare provides details on the adoption and implementation of advanced diagnostic techniques in different clinical settings, including population screening, clinical diagnosis, risk prediction, data-driven diagnosis, and remote healthcare monitoring. It also covers various cardiovascular diseases, from the macrovascular to microvascular levels, where early and accurate diagnosis is a high clinical need, for example, stroke, intracranial atherosclerosis, coronary artery disease, and microvascular dysfunction. The book is a practical guide with case studies, and the authors cover a wide range of cutting-edge diagnostic techniques, including artificial intelligence, radiological imaging, wearable sensors, genetic biomarkers, and multi-omics data integration. It summarizes the potentials, challenges, and ethical concerns in the implementation of these techniques under current clinical settings. It also discusses the future directions and perspectives for next-generation diagnostics based on AI-enhanced multimodal data fusion. This book targets a mixed audience of data scientists, engineers, clinicians, researchers, academics, and students interested in cutting-edge technologies, methodologies, and practices in the diagnostics of cardiovascular diseases to resolve the challenging gaps in healthcare and clinical applications.
Mass Spectrometry In Food Analysis Principles And Applications
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Author : Nerea Nunez
language : en
Publisher: World Scientific
Release Date : 2025-01-24
Mass Spectrometry In Food Analysis Principles And Applications written by Nerea Nunez and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-24 with Technology & Engineering categories.
Food manufacturers, researchers and society in general are becoming very interested in the quality, integrity and safety of food products. Within this context, and considering the complexity of the food chain in a globalized world where many players are involved between the production and consumption of a food product, together with the possible ways of food contamination such as environmental, agrochemical and food manipulation (packaging) sources, fast and reliable analytical methodologies to guarantee food quality, integrity and safety are required.Mass spectrometry therefore plays a relevant role in this field to satisfy the demands of sensitivity and selectivity for the analysis of complex food samples. In this book, new advances in mass spectrometry techniques in food analysis, involving their hyphenation with chromatographic and related separation techniques, as well as relevant applications reporting the determination of polyphenols, pesticides, mycotoxins, lipids, and peptides among other compounds, will be addressed.
Omics Technologies Toward Systems Biology
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Author : Fatemeh Maghuly
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-24
Omics Technologies Toward Systems Biology written by Fatemeh Maghuly and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-24 with Science categories.
Obesity
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Author : Karine Clement
language : en
Publisher: CRC Press
Release Date : 2007-09-12
Obesity written by Karine Clement and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-12 with Medical categories.
This book comprehensively accounts the current understanding of genetic mechanisms of obesity by analyzing obesity phenotypes and genotypes and, gene polymorphisms and mutations, and current results from animal model research and genetic studies in human models. By presenting the impact of genetic factors in the development of obesity and key molec