Statistical Methods For Mediation Confounding And Moderation Analysis Using R And Sas
DOWNLOAD
Download Statistical Methods For Mediation Confounding And Moderation Analysis Using R And Sas PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Statistical Methods For Mediation Confounding And Moderation Analysis Using R And Sas book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Statistical Methods For Mediation Confounding And Moderation Analysis Using R And Sas
DOWNLOAD
Author : Qingzhao Yu
language : en
Publisher: CRC Press
Release Date : 2022-03-14
Statistical Methods For Mediation Confounding And Moderation Analysis Using R And Sas written by Qingzhao Yu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-14 with Mathematics categories.
Third-variable effect refers to the effect transmitted by third-variables that intervene in the relationship between an exposure and a response variable. Differentiating between the indirect effect of individual factors from multiple third-variables is a constant problem for modern researchers. Statistical Methods for Mediation, Confounding and Moderation Analysis Using R and SAS introduces general definitions of third-variable effects that are adaptable to all different types of response (categorical or continuous), exposure, or third-variables. Using this method, multiple third- variables of different types can be considered simultaneously, and the indirect effect carried by individual third-variables can be separated from the total effect. Readers of all disciplines familiar with introductory statistics will find this a valuable resource for analysis. Key Features: Parametric and nonparametric method in third variable analysis Multivariate and Multiple third-variable effect analysis Multilevel mediation/confounding analysis Third-variable effect analysis with high-dimensional data Moderation/Interaction effect analysis within the third-variable analysis R packages and SAS macros to implement methods proposed in the book
Statistical Methods For Mediation Confounding And Moderationanalysis Using R And Sas
DOWNLOAD
Author : Qingzhao Yu
language : en
Publisher:
Release Date : 2022
Statistical Methods For Mediation Confounding And Moderationanalysis Using R And Sas written by Qingzhao Yu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Statistics categories.
Statistical Methods For Mediation Confounding And Moderation Analysis Using R And Sas
DOWNLOAD
Author : Qingzhao Yu
language : en
Publisher: CRC Press
Release Date : 2022-03-14
Statistical Methods For Mediation Confounding And Moderation Analysis Using R And Sas written by Qingzhao Yu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-14 with Mathematics categories.
Third-variable effect refers to the effect transmitted by third-variables that intervene in the relationship between an exposure and a response variable. Differentiating between the indirect effect of individual factors from multiple third-variables is a constant problem for modern researchers. Statistical Methods for Mediation, Confounding and Moderation Analysis Using R and SAS introduces general definitions of third-variable effects that are adaptable to all different types of response (categorical or continuous), exposure, or third-variables. Using this method, multiple third- variables of different types can be considered simultaneously, and the indirect effect carried by individual third-variables can be separated from the total effect. Readers of all disciplines familiar with introductory statistics will find this a valuable resource for analysis. Key Features: Parametric and nonparametric method in third variable analysis Multivariate and Multiple third-variable effect analysis Multilevel mediation/confounding analysis Third-variable effect analysis with high-dimensional data Moderation/Interaction effect analysis within the third-variable analysis R packages and SAS macros to implement methods proposed in the book
Introduction To Statistical Mediation Analysis
DOWNLOAD
Author : David MacKinnon
language : en
Publisher: Routledge
Release Date : 2012-10-02
Introduction To Statistical Mediation Analysis written by David MacKinnon and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-02 with Medical categories.
This volume introduces the statistical, methodological, and conceptual aspects of mediation analysis. Applications from health, social, and developmental psychology, sociology, communication, exercise science, and epidemiology are emphasized throughout. Single-mediator, multilevel, and longitudinal models are reviewed. The author's goal is to help the reader apply mediation analysis to their own data and understand its limitations. Each chapter features an overview, numerous worked examples, a summary, and exercises (with answers to the odd numbered questions). The accompanying CD contains outputs described in the book from SAS, SPSS, LISREL, EQS, MPLUS, and CALIS, and a program to simulate the model. The notation used is consistent with existing literature on mediation in psychology. The book opens with a review of the types of research questions the mediation model addresses. Part II describes the estimation of mediation effects including assumptions, statistical tests, and the construction of confidence limits. Advanced models including mediation in path analysis, longitudinal models, multilevel data, categorical variables, and mediation in the context of moderation are then described. The book closes with a discussion of the limits of mediation analysis, additional approaches to identifying mediating variables, and future directions. Introduction to Statistical Mediation Analysis is intended for researchers and advanced students in health, social, clinical, and developmental psychology as well as communication, public health, nursing, epidemiology, and sociology. Some exposure to a graduate level research methods or statistics course is assumed. The overview of mediation analysis and the guidelines for conducting a mediation analysis will be appreciated by all readers.
Introduction To Mediation Moderation And Conditional Process Analysis
DOWNLOAD
Author : Andrew F. Hayes
language : en
Publisher: Guilford Publications
Release Date : 2022-01-24
Introduction To Mediation Moderation And Conditional Process Analysis written by Andrew F. Hayes and has been published by Guilford Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-24 with Social Science categories.
Acclaimed for its thorough presentation of mediation, moderation, and conditional process analysis, this book has been updated to reflect the latest developments in PROCESS for SPSS, SAS, and, new to this edition, R. Using the principles of ordinary least squares regression, Andrew F. Hayes illustrates each step in an analysis using diverse examples from published studies, and displays SPSS, SAS, and R code for each example. Procedures are outlined for estimating and interpreting direct, indirect, and conditional effects; probing and visualizing interactions; testing hypotheses about the moderation of mechanisms; and reporting different types of analyses. Readers gain an understanding of the link between statistics and causality, as well as what the data are telling them. The companion website (www.afhayes.com) provides data for all the examples, plus the free PROCESS download. New to This Edition *Rewritten Appendix A, which provides the only documentation of PROCESS, including a discussion of the syntax structure of PROCESS for R compared to SPSS and SAS. *Expanded discussion of effect scaling and the difference between unstandardized, completely standardized, and partially standardized effects. *Discussion of the meaning of and how to generate the correlation between mediator residuals in a multiple-mediator model, using a new PROCESS option. *Discussion of a method for comparing the strength of two specific indirect effects that are different in sign. *Introduction of a bootstrap-based Johnson–Neyman-like approach for probing moderation of mediation in a conditional process model. *Discussion of testing for interaction between a causal antecedent variable [ital]X[/ital] and a mediator [ital]M[/ital] in a mediation analysis, and how to test this assumption in a new PROCESS feature.
Statistical Analytics For Health Data Science With Sas And R
DOWNLOAD
Author : Jeffrey Wilson
language : en
Publisher: CRC Press
Release Date : 2023-03-27
Statistical Analytics For Health Data Science With Sas And R written by Jeffrey Wilson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-27 with Business & Economics categories.
This book aims to compile typical fundamental-to-advanced statistical methods to be used for health data sciences. Although the book promotes applications to health and health-related data, the models in the book can be used to analyze any kind of data. The data are analyzed with the commonly used statistical software of R/SAS (with online supplementary on SPSS/Stata). The data and computing programs will be available to facilitate readers’ learning experience. There has been considerable attention to making statistical methods and analytics available to health data science researchers and students. This book brings it all together to provide a concise point-of-reference for the most commonly used statistical methods from the fundamental level to the advanced level. We envisage this book will contribute to the rapid development in health data science. We provide straightforward explanations of the collected statistical theory and models, compilations of a variety of publicly available data, and illustrations of data analytics using commonly used statistical software of SAS/R. We will have the data and computer programs available for readers to replicate and implement the new methods. The primary readers would be applied data scientists and practitioners in any field of data science, applied statistical analysts and scientists in public health, academic researchers, and graduate students in statistics and biostatistics. The secondary readers would be R&D professionals/practitioners in industry and governmental agencies. This book can be used for both teaching and applied research.
Design And Analysis Of Pragmatic Trials
DOWNLOAD
Author : Song Zhang
language : en
Publisher: CRC Press
Release Date : 2023-05-16
Design And Analysis Of Pragmatic Trials written by Song Zhang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-16 with Medical categories.
This book begins with an introduction of pragmatic cluster randomized trials (PCTs) and reviews various pragmatic issues that need to be addressed by statisticians at the design stage. It discusses the advantages and disadvantages of each type of PCT, and provides sample size formulas, sensitivity analyses, and examples for sample size calculation. The generalized estimating equation (GEE) method will be employed to derive sample size formulas for various types of outcomes from the exponential family, including continuous, binary, and count variables. Experimental designs that have been frequently employed in PCTs will be discussed, including cluster randomized designs, matched-pair cluster randomized design, stratified cluster randomized design, stepped-wedge cluster randomized design, longitudinal cluster randomized design, and crossover cluster randomized design. It demonstrates that the GEE approach is flexible to accommodate pragmatic issues such as hierarchical correlation structures, different missing data patterns, randomly varying cluster sizes, etc. It has been reported that the GEE approach leads to under-estimated variance with limited numbers of clusters. The remedy for this limitation is investigated for the design of PCTs. This book can assist practitioners in the design of PCTs by providing a description of the advantages and disadvantages of various PCTs and sample size formulas that address various pragmatic issues, facilitating the proper implementation of PCTs to improve health care. It can also serve as a textbook for biostatistics students at the graduate level to enhance their knowledge or skill in clinical trial design. Key Features: Discuss the advantages and disadvantages of each type of PCTs, and provide sample size formulas, sensitivity analyses, and examples. Address an unmet need for guidance books on sample size calculations for PCTs; A wide variety of experimental designs adopted by PCTs are covered; The sample size solutions can be readily implemented due to the accommodation of common pragmatic issues encountered in real-world practice; Useful to both academic and industrial biostatisticians involved in clinical trial design; Can be used as a textbook for graduate students majoring in statistics and biostatistics.
Case Studies In Bayesian Methods For Biopharmaceutical Cmc
DOWNLOAD
Author : Paul Faya
language : en
Publisher: CRC Press
Release Date : 2022-12-15
Case Studies In Bayesian Methods For Biopharmaceutical Cmc written by Paul Faya and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-15 with Mathematics categories.
The subject of this book is applied Bayesian methods for chemistry, manufacturing, and control (CMC) studies in the biopharmaceutical industry. The book has multiple authors from industry and academia, each contributing a case study (chapter). The collection of case studies covers a broad array of CMC topics, including stability analysis, analytical method development, specification setting, process development and optimization, process control, experimental design, dissolution testing, and comparability studies. The analysis of each case study includes a presentation of code and reproducible output. This book is written with an academic level aimed at practicing nonclinical biostatisticians, most of whom have graduate degrees in statistics. • First book of its kind focusing strictly on CMC Bayesian case studies • Case studies with code and output • Representation from several companies across the industry as well as academia • Authors are leading and well-known Bayesian statisticians in the CMC field • Accompanying website with code for reproducibility • Reflective of real-life industry applications/problems
Advanced Statistics In Regulatory Critical Clinical Initiatives
DOWNLOAD
Author : Wei Zhang
language : en
Publisher: CRC Press
Release Date : 2022-05-25
Advanced Statistics In Regulatory Critical Clinical Initiatives written by Wei Zhang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-25 with Mathematics categories.
Advanced Statistics in Regulatory Critical Clinical Initiatives is focused on the critical clinical initiatives introduced by the 21st Century Cure Act passed by the United States Congress in December 2016. The book covers everything from the outline of the initiatives to analysis on the effect on biopharmaceutical research and development. Advanced Statistics in Regulatory Critical Clinical Initiatives provides innovative ways to resolve common challenges in statistical research of rare diseases such small sample sizes and provides guidance for combined use of data. With analysis from regulatory and scientific perspectives this book is an ideal companion for researchers in biostatistics, pharmaceutical development, and policy makers in related fields. Key Features: Provides better understanding of innovative design and analysis of each critical clinical initiatives which may be used in regulatory review/approval of drug development. Makes recommendations to evaluate submissions accurately and reliably. Proposes innovative study designs and statistical methods for oncology and/or rare disease drug development. Provides insight regarding current regulatory guidance on drug development such as gene therapy and rare diseases.
Medical Statistics For Cancer Studies
DOWNLOAD
Author : Trevor F. Cox
language : en
Publisher: CRC Press
Release Date : 2022-06-23
Medical Statistics For Cancer Studies written by Trevor F. Cox and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-23 with Mathematics categories.
Cancer is a dreaded disease. One in two people will be diagnosed with cancer within their lifetime. Medical Statistics for Cancer Studies shows how cancer data can be analysed in a variety of ways, covering cancer clinical trial data, epidemiological data, biological data, and genetic data. It gives some background in cancer biology and genetics, followed by detailed overviews of survival analysis, clinical trials, regression analysis, epidemiology, meta-analysis, biomarkers, and cancer informatics. It includes lots of examples using real data from the author’s many years of experience working in a cancer clinical trials unit. Features: A broad and accessible overview of statistical methods in cancer research Necessary background in cancer biology and genetics Details of statistical methodology with minimal algebra Many examples using real data from cancer clinical trials Appendix giving statistics revision.