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Statistical Theory And Analysis In Bioassay


Statistical Theory And Analysis In Bioassay
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Statistical Theory And Analysis In Bioassay


Statistical Theory And Analysis In Bioassay
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Author : Uchenna Petronilla Ogoke
language : en
Publisher: IPS Intelligentsia Publishing Services
Release Date : 2021-08-21

Statistical Theory And Analysis In Bioassay written by Uchenna Petronilla Ogoke and has been published by IPS Intelligentsia Publishing Services this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-21 with Medical categories.


Statistical Theory and Analysis in Bioassay is a seven chapter monograph tailored essentially to meet the needs of graduate students, practitioners and researchers in the fields of medicine, pharmacology, biosciences/life sciences and related fields that employs the tools of biostatistics in bioassays and analysis. In this wise, we have taken time to discuss in details relevant topics; principles, methods and applications. Practice exercises are also included where necessary. The earlier chapters give background information, definition of terms, purpose, types, structure and relative potency in bioassay. An important theorem, Fieller’s theorem is proved in details with illustrative examples. The last two chapters are on dose-response relationship, fitting in parallelline assays and estimation. We are convinced that this monograph will meet the expectations of the readers while constructive criticisms that will improve another edition will be appreciated.



Biostatistics For Bioassay


Biostatistics For Bioassay
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Author : Ann Yellowlees
language : en
Publisher: CRC Press
Release Date : 2024-12-24

Biostatistics For Bioassay written by Ann Yellowlees and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-24 with Mathematics categories.


In recent decades, there has been enormous growth in biologics research and development, with the accompanying development of biological assays for emerging products. In parallel, there have been substantial advances in statistical methodology, as well as technological advances in computer power, enabling new techniques to be implemented via statistical software. Biostatistics for Bioassay presents an overview of the statistical analysis techniques that are needed in order to report the results of biological assays. These assays are needed for testing all biological medicines, such as vaccines and cell therapies, to allow them to be released for use. Beginning with consideration of the performance characteristics required of a bioassay, including accuracy, precision, and combinations of these two attributes, the book builds a framework for statistical bioassay design. Features: Explains the statistical methods needed at each stage of the lifecycle of a bioassay Describes the demonstration of the bioassay’s performance, known as validation Covers the statistical techniques for monitoring the bioassay’s performance over time Details how to transfer the bioassay to another laboratory or replace critical reagents Provides examples at every stage, to allow the reader to work through the techniques and consolidate their understanding The book provides a resource for interested bioassay analysts, and statisticians working with bioassays. In bringing together best practices in statistics across the bioassay lifecycle into a single volume, it aims to provide a comprehensive and useful textbook for statistical analysis in bioassay.



The Statistics Of Bioassay


The Statistics Of Bioassay
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Author : C. I. Bliss
language : en
Publisher: Elsevier
Release Date : 2014-05-12

The Statistics Of Bioassay written by C. I. Bliss and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.


The Statistics of Bioassay: With Special Reference to the Vitamins, Volume II focuses on the processes, reactions, principles, and approaches involved in the biological assay of vitamins. The publication first offers information on the general principles of biological assay, dosage-response curve and its error, and designs for segregating nonrandom variation. Discussions focus on replacement of missing values, randomized groups, calculation of the line, analysis of the variation about the line, comparative biological assays, analytical biological assays, and determination of activity. The text then ponders on measurement of relative potency and correction of quantitative variables. The manuscript takes a look at assays where the variation in response is a function of the dose and slope-ratio assays. Topics include microbiological assays and the slope-ratio technique, analysis of balanced slope-ratio assays, analysis of assays with an all-or-none response, and graded response with unequal variance. The publication then tackles multiple or repeated assays, including quality control in repeated assays and combination of independent assays of a single unknown. The publication is a valuable source of information for researchers interested in the biological assay of vitamins.



Jnci Journal Of The National Cancer Institute


Jnci Journal Of The National Cancer Institute
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Author : National Cancer Institute (U.S.)
language : en
Publisher:
Release Date : 1980

Jnci Journal Of The National Cancer Institute written by National Cancer Institute (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Cancer categories.




Ucsf Graduate Division Bulletin


Ucsf Graduate Division Bulletin
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Author : University of California, San Francisco. Graduate Division
language : en
Publisher:
Release Date : 1962

Ucsf Graduate Division Bulletin written by University of California, San Francisco. Graduate Division and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1962 with Medicine categories.




Statistical Theory And Method Abstracts


Statistical Theory And Method Abstracts
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Author :
language : en
Publisher:
Release Date : 2001

Statistical Theory And Method Abstracts written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Statistics categories.




Bioassays Of Entomopathogenic Microbes And Nematodes


Bioassays Of Entomopathogenic Microbes And Nematodes
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Author : Amos Navon
language : en
Publisher: CABI
Release Date : 2000-01-01

Bioassays Of Entomopathogenic Microbes And Nematodes written by Amos Navon and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-01 with Science categories.


This volume provides background theory and practical protocols for bioassays of bacteria, viruses, fungi and nematodes that can be used as biological control agents against insect pests of agricultural and medical importance.



Statistics In The Pharmaceutical Industry 3rd Edition


Statistics In The Pharmaceutical Industry 3rd Edition
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Author : Charles Ralph Buncher
language : en
Publisher: CRC Press
Release Date : 1993-11-17

Statistics In The Pharmaceutical Industry 3rd Edition written by Charles Ralph Buncher and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-17 with Mathematics categories.


This rewritten and updated second edition provides comprehensive information on the wide-ranging applications of statistics in the pharmacological field. Focusing on practical aspects, it sets out to bridge the gap between industry and academia.;Reflecting the changes that have taken place since publication of the first edition, this volume covers new topics such as: cancer clinical trials, clinical trials of AIDS patients and animal tumorigenicity studies; the development of antiepileptic drugs; the role of epidemiology in postmarketing trials and adverse drug experience; computer-assisted new drug application (CANDA) submissions; contract research organizations; interim analysis in clinical trials; and room-temperature tests for the stability of drugs.;This work is intended as: a reference for statisticians, biostatisticians, pharmacologists, administrators, managers, and scientists in the pharmaceutical industry; and a text for graduate students taking courses in applied statistics or pharmaceutical statistics.



Research Methods In Toxicology And Insecticide Resistance Monitoring Of Rice Planthoppers


Research Methods In Toxicology And Insecticide Resistance Monitoring Of Rice Planthoppers
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Author :
language : en
Publisher: Int. Rice Res. Inst.
Release Date : 2011

Research Methods In Toxicology And Insecticide Resistance Monitoring Of Rice Planthoppers written by and has been published by Int. Rice Res. Inst. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Planthoppers categories.